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The Cancer Chemoprotection Program

The Cancer Chemoprotection Program identifies previously unstudied phytochemicals (chemicals from plants that may affect health) and develops existing phytochemicals as supplements that can protect against different types of cancer, including colorectal, breast, prostate, and liver cancer. We are interested in understanding the molecular mechanisms responsible for the anticancer effect of certain dietary compounds, such as tea catechins, sulforaphane, indole-3-carbinol, allyl sulfides, chlorophyll, and zinc. We are also interested in epigenetic effects that modulate cancer risk across the lifespan, from the fetus to adulthood.


Cancer Chemoprotection for the Fetus and Infant

Principal Investigator: David E. Williams, Ph.D.

Zinc and Antioxidants in Cancer Chemoprevention

Principal Investigator: Emily Ho, Ph.D.

Dietary Interventions for Cancer Prevention

Principal Investigator: Gerd Bobe, Ph.D., M.P.H.

Role of Drug-metabolizing Enzymes in Health and Disease

Principal Investigator: Sharon Krueger, Ph.D.

Vitamin E Metabolism and Mechanisms for Chemoprotection and Chemotherapy

Principal Investigator: Debbie J. Mustacich, Ph.D.