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Cardiovascular and Metabolic Diseases

The work performed in the laboratories of the Cardiovascular and Metabolic Diseases program is aimed at a better understanding of the molecular and cellular mechanisms of cardiovascular diseases (primarily heart disease, stroke, and hypertension), metabolic syndrome, fatty liver disease, and type II diabetes. The role of oxidative stress and inflammation in the causation of these diseases is being investigated, as well as the protective effects of micronutrients and other dietary factors or supplements, such as vitamins C and E, lipoic acid, fish oil, and flavonoids.

Dietary Antioxidants, Vascular Inflammation, and Heart Disease

Principal Investigator: Balz Frei, Ph.D.

Vitamin E in Human Health

Principal Investigator: Maret G. Traber, Ph.D.

Metabolism of Dietary and Endogenous Fats

Principal Investigator: Donald B. Jump, Ph.D.

Vitamin C, Lipid Peroxidation, and Oxidative Stress

Principal Investigator: Fred Stevens, Ph.D.

Role of Lipoic Acid in Vascular Inflammation and Atherosclerosis

Principal Investigator: Weijian Zhang, Ph.D.