Antioxidants, Nutrition, and Gene Expression in Health and Disease Principal Investigator: Tammy Bray, Ph.D.
The focus of my research is to use a "whole foods" approach to investigate the role of antioxidant and anti-inflammatory components of food in the prevention of chronic diseases, including diabetes and cancer. The specific aims of the research are to 1) elucidate the mechanisms by which antioxidant and anti-inflammatory nutrients reduce oxidative stress and prevent free radical-mediated diseases, 2) understand how nutritional deficiency in quantity and quality exacerbates oxidative stress and enhances the susceptibility to free radical-mediated diseases, and 3) understand the effect of a good diet in masking the expression of bad genes in the development of chronic diseases.