The conference will be held at the CH2M Hill Alumni Center on the Oregon State University campus. Saturday afternoon activities for the public will also be on campus.
| 1:00 PM | Registration begins at the CH2M Hill Alumni Center on the Oregon State University campus |
| 2:30 | Welcome and opening remarks Balz Frei, PhD, Conference Chair Linus Pauling Institute, Oregon State University, Corvallis, OR |
| OMEGA-3 FATTY ACIDS IN CARDIOVASCULAR AND METABOLIC DISEASE PREVENTION | |
Chairs: Maret G. Traber, PhD, Linus Pauling Institute, |
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| 2:45 - 3:15 | Health benefits of omega-3 fatty acids Richard Deckelbaum, MD Columbia University, New York, NY |
| 3:15 - 3:45 | Stearidonic acid, omega-3 index and cardiovascular diseases William S. Harris, PhD Health Diagnostic Laboratory, Inc., Richmond, VA |
| 3:45 - 4:15 | Omega-3 fatty acids, cardiac mitochondrial function and heart failure: From lipotoxicity to lipoprotection William C. Stanley, PhD University of Sydney, Sydney, Australia |
| 4:15 - 4:45 | Prospective cohort studies and randomized controlled trials on omega-3 fatty acids and cardiovascular diseases Dariush Mozaffarian, MD, DrPH Harvard School of Public Health, Boston, MA |
| 4:45 - 5:15 | Omega-3 fatty acids and non-alcoholic fatty liver disease Donald B. Jump, PhD School of Biological and Population Health Sciences and Linus Pauling Institute, Oregon State University, Corvallis, OR |
| 6:30 | Welcome Reception |
| 6:00 AM | Organized Walk/Run |
| 7:15 - 8:00 | Breakfast provided |
| VITAMIN D – HEALTH BENEFITS BEYOND BONE | |
Chair: Adrian "Fritz" Gombart, PhD |
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| 8:00 - 8:30 | Vitamin D requirements for optimum health Robert P. Heaney, MD Creighton University, Omaha, NE |
| 8:30 - 9:00 | Vitamin D and the brain Thomas H. J. Burne, PhD The University of Queensland, St. Lucia, Queensland, Australia |
| 9:00 - 9:30 | Vitamin D and cancer prevention: Calcitriol and dietary vitamin D3 exhibit substantial anti-cancer activity in mouse models of breast cancer in lean and obese mice David Feldman, MD Stanford University School of Medicine, Stanford, CA |
| 9:30 - 10:00 | Vitamin D and cardiovascular disease Stefan Pilz, MD, PhD Medical University of Graz, Graz, Austria |
| 10:00 - 10:30 | Coffee/Tea Break |
| HEALTH EFFECTS AND MECHANISMS OF ACTION OF XANTHOHUMOL | |
Chair: Fred Stevens, PhD |
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| 10:30 - 11:00 | Xanthohumol inhibits hyaluronan export and prevents osteoarthritis Peter Prehm, PhD Münster University Hospital, Münster, Germany |
| 11:00 - 11:30 | Hops, xanthohumol and women's health Richard B. van Breemen, PhD University of Illinois, Chicago, IL |
| 11:30 - 12:00 | Xanthohumol for treatment of metabolic syndrome Fred Stevens, PhD Linus Pauling Institute, Oregon State University, Corvallis, OR |
| 12:00 - 1:30 | Lunch provided (LaSells Stewart Center) |
| DIET AND EPIGENETIC IMPACTS ON DISEASE AND AGING | |
Chairs: Rod Dashwood, PhD, and Tory Hagen, PhD |
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| 1:30 - 2:00 | Diet, epigenetics and fetal origin of adult-onset diseases Kent Thornburg, PhD Oregon Health & Science University, Portland, OR |
| 2:00 - 2:30 | Nutritional influences on epigenetics and age-related diseases Sang-Woon Choi, MD, PhD Jean Mayer USDA HNRC on Aging at Tufts University, Boston, MA |
| 2:30 - 3:00 | Folic acid deficiency, aortic plaque formation and DNA methylation in vascular tissue Susan Duthie, PhD University of Aberdeen, Aberdeen, UK |
| 3:00 - 3:30 | Coffee/Tea Break |
| 3:30 - 4:00 | Bioactive food compounds and epigenetic mechanisms in breast cancer Donato Romagnolo, PhD The University of Arizona Cancer Center, Tucson, AZ |
| 4:00 - 4:30 | DNA methylation profiling as an epigenetic approach to cancer prevention Clarissa Gerhäuser, PhD German Cancer Research Center (DKFZ), Heidelberg, Germany |
| 4:30 - 5:00 | Modulation of microRNA profiles by dietary chemopreventive agents
Alberto Izzotti, MD, PhD University of Genoa, Genoa, Italy |
| 5:00 - 7:00 | Poster Session (hors d'oeuvres and beverages provided) |
| 6:00 AM | Organized Walk/Run |
| 7:30 - 8:30 | Breakfast provided |
| HEALTH BENEFITS OF VITAMIN C: BEYOND SCURVY | |
Chair: Balz Frei, PhD | |
| 8:30 - 9:00 | Chemical biology of pharmacological ascorbate to treat cancer Garry Buettner, PhD The University of Iowa, Iowa City, IA |
| 9:00 - 9:30 | Vitamin C supplementation effects on blood pressure Edgar R. Miller III, PhD, MD The Johns Hopkins University School of Medicine, Baltimore, MD |
| 9:30 - 10:00 | Vitamin C in brain aging and cognitive function Fiona Harrison, PhD Vanderbilt University School of Medicine, Nashville, TN |
| 10:00 - 10:30 | Coffee/Tea Break |
| MICRONUTRIENTS IN FERTILITY AND PREGNANCY | |
Chair: David E. Williams, PhD | |
| 10:30 - 11:00 | Achieving optimal folate status: Why and how? Helene McNulty, PhD University of Ulster, Coleraine, Northern Ireland |
| 11:00 - 11:30 | Role of micronutrients in human fertility Kelton Tremellen, PhD Repromed, Adelaide, South Australia, Australia |
| 11:30 - 12:00 | Micronutrients and the developing brain Victoria Hall Moran, PhD University of Central Lancashire, Preston, UK |
| 12:00 - 1:05 | Lunch provided (LaSells Stewart Center) |
| ORAL ABSTRACTS | |
Chairs: Viviana Perez, PhD, and Kathy Magnusson, DVM, PhD | |
| 1:10 - 1:30 | Omega-3 fatty acids and white matter mediated cognitive decline in older adults Gene Bowman Oregon Health & Science University, Portland, Oregon |
| 1:30 - 1:50 | Acute effects of different multi-vitamin/mineral preparations with and without guaraná on mood, cognitive performance and functional brain activation Andrew Scholey Swinburne University, Melbourne, Victoria, Australia |
| 1:50 - 2:10 | Ascorbic acid supplementation modulates gene expression in peripheral blood mononuclear cells specifically upon an inflammatory stimulus: A pilot study. Özgür Sancak Bayer Consumer Care Ltd., Basel, Switzerland |
| 2:10 - 2:30 | Tumor levels of vitamin C are associated with hypoxia-inducible factor-1 and disease-free survival in colorectal cancer Margreet Vissers University of Otago, Christchurch, New Zealand |
| 2:30 - 2:50 | Genome-wide transcriptome analysis of the effects of sulforaphane on normal and prostate cancer cells Laura Beaver School of Biological and Population Health Sciences and Linus Pauling Institute, Oregon State University, Corvallis, Oregon |
| 2:50 - 3:10 | The effects of phytophenols in fruit and vegetables on antioxidant potentials, global protein expression and genomic instability Joanna Kaniewska Rowett Institute of Nutrition and Health, University of Aberdeen, United Kingdom |
| 3:10 - 3:30 | Complementary roles in cancer prevention: Soy protease inhibitor makes cancer preventive lunasin peptide bioavailable Ben O. de Lumen University of California at Berkeley, Berkeley, California |
| 3:30 - 3:50 | Vitamin D and aging: Unraveling the regulatory axis between vitamin D and klotho John S. Finnell AOMA Graduate School of Integrative Medicine, Austin, Texas |
| 3:50 - 4:15 | Coffee/Tea Break |
| AWARD CEREMONY | |
| 4:15 | Presentation by LPI Director Balz Frei, PhD Plenary Lecture by Awardee |
| 6:30 | Reception |
| 7:30 | Banquet Dinner |
| PUBLIC SESSION | |
| Co-sponsored by the Moore Family Center for Whole Grain Foods, Nutrition and Preventive Health, Oregon State University | |
Chairs: Emily Ho, PhD, and Balz Frei, PhD | |
| 9:00 - 9:30 | Healthy dietary patterns in the prevention of breast cancer and metabolic syndrome Cynthia A. Thomson, PhD The University of Arizona Cancer Center, Tucson, AZ |
| 9:30 - 10:00 | Effects of whole grains and nuts on cardiometabolic syndrome risk factors Penny Kris-Etherton, PhD The Pennsylvania State University, University Park, PA |
| 10:00 - 10:30 | Polyphenols and health—More than just a berry good idea Eric Rimm, ScD Harvard School of Public Health, Boston, MA |
| 10:30 - 11:00 | Coffee/Tea Break |
| 11:00 - 11:30 | An integrative, family-based approach to childhood obesity David Ludwig, MD, PhD Harvard University, Boston, MA |
| 11:30 - 12:00 | Panel Discussion/Questions and Answers |
| Afternoon activities sponsored by the Healthy Youth Program of the Linus Pauling Institute | |
| noon | Lunch with researchers at the Linus Pauling Science Center |
| 1:00 - 3:00 | Tours at the Linus Pauling Science Center and the Oregon State University Libraries Special Collections & Archives Research Center |
Register for lunch and afternoon tours, and get more information about the public day, by emailing HYP@oregonstate.edu
