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Diet and Optimum Health Conference

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The conference will be held at the CH2M Hill Alumni Center on the Oregon State University campus. Saturday afternoon activities for the public will also be on campus.

Conference Program


Wednesday, May 15, 2013


1:00 PM Registration begins at the CH2M Hill Alumni Center on the Oregon State University campus
2:30 Welcome and opening remarks
Balz Frei, PhD, Conference Chair
Linus Pauling Institute, Oregon State University, Corvallis, OR

OMEGA-3 FATTY ACIDS IN CARDIOVASCULAR AND METABOLIC DISEASE PREVENTION

Chairs: Maret G. Traber, PhD, Linus Pauling Institute,
Oregon State University, Corvallis, OR, and
Pamela Starke-Reed, PhD, National Institutes of Health,
Bethesda, MD

2:45 - 3:15 Health benefits of omega-3 fatty acids
Richard Deckelbaum, MD
Columbia University, New York, NY
3:15 - 3:45 Stearidonic acid, omega-3 index and cardiovascular diseases
William S. Harris, PhD
Health Diagnostic Laboratory, Inc., Richmond, VA
3:45 - 4:15 Omega-3 fatty acids, cardiac mitochondrial function and heart failure: From lipotoxicity to lipoprotection
William C. Stanley, PhD
University of Sydney, Sydney, Australia
4:15 - 4:45 Prospective cohort studies and randomized controlled trials on omega-3 fatty acids and cardiovascular diseases
Dariush Mozaffarian, MD, DrPH
Harvard School of Public Health, Boston, MA
4:45 - 5:15 Omega-3 fatty acids and non-alcoholic fatty liver disease
Donald B. Jump, PhD
School of Biological and Population Health Sciences and Linus Pauling Institute, Oregon State University, Corvallis, OR
6:30 Welcome Reception

Thursday, May 16, 2013


6:00 AM Organized Walk/Run
7:15 - 8:00 Breakfast provided

VITAMIN D – HEALTH BENEFITS BEYOND BONE

Chair: Adrian "Fritz" Gombart, PhD
Linus Pauling Institute, Oregon State University, Corvallis, OR

8:00 - 8:30 Vitamin D requirements for optimum health
Robert P. Heaney, MD
Creighton University, Omaha, NE
8:30 - 9:00 Vitamin D and the brain
Thomas H. J. Burne, PhD
The University of Queensland, St. Lucia, Queensland, Australia
9:00 - 9:30 Vitamin D and cancer prevention: Calcitriol and dietary vitamin D3 exhibit substantial anti-cancer activity in mouse models of breast cancer in lean and obese mice
David Feldman, MD
Stanford University School of Medicine, Stanford, CA
9:30 - 10:00 Vitamin D and cardiovascular disease
Stefan Pilz, MD, PhD
Medical University of Graz, Graz, Austria
10:00 - 10:30 Coffee/Tea Break

HEALTH EFFECTS AND MECHANISMS OF ACTION OF XANTHOHUMOL

Chair: Fred Stevens, PhD
Linus Pauling Institute, Oregon State University, Corvallis, OR

10:30 - 11:00 Xanthohumol inhibits hyaluronan export and prevents osteoarthritis
Peter Prehm, PhD
Münster University Hospital, Münster, Germany
11:00 - 11:30 Hops, xanthohumol and women's health
Richard B. van Breemen, PhD
University of Illinois, Chicago, IL
11:30 - 12:00 Xanthohumol for treatment of metabolic syndrome
Fred Stevens, PhD
Linus Pauling Institute, Oregon State University, Corvallis, OR
12:00 - 1:30 Lunch provided (LaSells Stewart Center)

DIET AND EPIGENETIC IMPACTS ON DISEASE AND AGING

Chairs: Rod Dashwood, PhD, and Tory Hagen, PhD
Linus Pauling Institute, Oregon State University, Corvallis, OR

1:30 - 2:00 Diet, epigenetics and fetal origin of adult-onset diseases
Kent Thornburg, PhD
Oregon Health & Science University, Portland, OR
2:00 - 2:30 Nutritional influences on epigenetics and age-related diseases
Sang-Woon Choi, MD, PhD
Jean Mayer USDA HNRC on Aging at Tufts University, Boston, MA
2:30 - 3:00 Folic acid deficiency, aortic plaque formation and DNA methylation in vascular tissue
Susan Duthie, PhD
University of Aberdeen, Aberdeen, UK
3:00 - 3:30 Coffee/Tea Break
3:30 - 4:00 Bioactive food compounds and epigenetic mechanisms in breast cancer
Donato Romagnolo, PhD
The University of Arizona Cancer Center, Tucson, AZ
4:00 - 4:30 DNA methylation profiling as an epigenetic approach to cancer prevention
Clarissa Gerhäuser, PhD
German Cancer Research Center (DKFZ), Heidelberg, Germany
4:30 - 5:00 Modulation of microRNA profiles by dietary chemopreventive agents
Alberto Izzotti, MD, PhD
University of Genoa, Genoa, Italy
5:00 - 7:00 Poster Session (hors d'oeuvres and beverages provided)

Friday, May 17, 2013


6:00 AM Organized Walk/Run
7:30 - 8:30 Breakfast provided

HEALTH BENEFITS OF VITAMIN C: BEYOND SCURVY

Chair: Balz Frei, PhD
Linus Pauling Institute, Oregon State University, Corvallis, OR

8:30 - 9:00 Chemical biology of pharmacological ascorbate to treat cancer
Garry Buettner, PhD
The University of Iowa, Iowa City, IA
9:00 - 9:30 Vitamin C supplementation effects on blood pressure
Edgar R. Miller III, PhD, MD
The Johns Hopkins University School of Medicine, Baltimore, MD
9:30 - 10:00 Vitamin C in brain aging and cognitive function
Fiona Harrison, PhD
Vanderbilt University School of Medicine, Nashville, TN
10:00 - 10:30 Coffee/Tea Break

MICRONUTRIENTS IN FERTILITY AND PREGNANCY

Chair: David E. Williams, PhD
Linus Pauling Institute, Oregon State University, Corvallis, OR

10:30 - 11:00 Achieving optimal folate status: Why and how?
Helene McNulty, PhD
University of Ulster, Coleraine, Northern Ireland
11:00 - 11:30 Role of micronutrients in human fertility
Kelton Tremellen, PhD
Repromed, Adelaide, South Australia, Australia
11:30 - 12:00 Micronutrients and the developing brain
Victoria Hall Moran, PhD
University of Central Lancashire, Preston, UK
12:00 - 1:05 Lunch provided (LaSells Stewart Center)
 

ORAL ABSTRACTS

Chairs: Viviana Perez, PhD, and Kathy Magnusson, DVM, PhD
Linus Pauling Institute, Oregon State University, Corvallis, OR

1:10 - 1:30 Omega-3 fatty acids and white matter mediated cognitive decline in older adults
Gene Bowman
Oregon Health & Science University, Portland, Oregon
1:30 - 1:50 Acute effects of different multi-vitamin/mineral preparations with and without guaraná on mood, cognitive performance and functional brain activation
Andrew Scholey
Swinburne University, Melbourne, Victoria, Australia
1:50 - 2:10 Ascorbic acid supplementation modulates gene expression in peripheral blood mononuclear cells specifically upon an inflammatory stimulus: A pilot study.
Özgür Sancak
Bayer Consumer Care Ltd., Basel, Switzerland
2:10 - 2:30 Tumor levels of vitamin C are associated with hypoxia-inducible factor-1 and disease-free survival in colorectal cancer
Margreet Vissers
University of Otago, Christchurch, New Zealand
2:30 - 2:50 Genome-wide transcriptome analysis of the effects of sulforaphane on normal and prostate cancer cells
Laura Beaver
School of Biological and Population Health Sciences and Linus Pauling Institute, Oregon State University, Corvallis, Oregon
2:50 - 3:10 The effects of phytophenols in fruit and vegetables on antioxidant potentials, global protein expression and genomic instability
Joanna Kaniewska
Rowett Institute of Nutrition and Health, University of Aberdeen, United Kingdom
3:10 - 3:30 Complementary roles in cancer prevention: Soy protease inhibitor makes cancer preventive lunasin peptide bioavailable
Ben O. de Lumen
University of California at Berkeley, Berkeley, California
3:30 - 3:50 Vitamin D and aging: Unraveling the regulatory axis between vitamin D and klotho
John S. Finnell
AOMA Graduate School of Integrative Medicine, Austin, Texas
3:50 - 4:15 Coffee/Tea Break
 

AWARD CEREMONY
Linus Pauling Institute Prize for Health Research

4:15 Presentation by LPI Director Balz Frei, PhD
Plenary Lecture by Awardee
6:30 Reception
7:30 Banquet Dinner

Saturday, May 18, 2013


PUBLIC SESSION
WHOLE-FOOD APPROACHES TO DISEASE PREVENTION

Co-sponsored by the Moore Family Center for Whole Grain Foods, Nutrition and Preventive Health, Oregon State University

Chairs: Emily Ho, PhD, and Balz Frei, PhD
Linus Pauling Institute, Oregon State University, Corvallis, OR

9:00 - 9:30 Healthy dietary patterns in the prevention of breast cancer and metabolic syndrome
Cynthia A. Thomson, PhD
The University of Arizona Cancer Center, Tucson, AZ
9:30 - 10:00 Effects of whole grains and nuts on cardiometabolic syndrome risk factors
Penny Kris-Etherton, PhD
The Pennsylvania State University, University Park, PA
10:00 - 10:30 Polyphenols and health—More than just a berry good idea
Eric Rimm, ScD
Harvard School of Public Health, Boston, MA
10:30 - 11:00 Coffee/Tea Break
11:00 - 11:30 An integrative, family-based approach to childhood obesity
David Ludwig, MD, PhD
Harvard University, Boston, MA
11:30 - 12:00 Panel Discussion/Questions and Answers
Afternoon activities sponsored by the Healthy Youth Program of the Linus Pauling Institute
noon Lunch with researchers at the Linus Pauling Science Center
1:00 - 3:00 Tours at the Linus Pauling Science Center and the Oregon State University Libraries Special Collections & Archives Research Center

Register for lunch and afternoon tours, and get more information about the public day, by emailing HYP@oregonstate.edu