In this issue of the Newsletter, we feature the research of some of the OSU faculty members who have made many important contributions to nutrition research. These investigations include studies on the prevention of muscle disorders by selenium, the prevention of cancer with dietary anticarcinogens, and the identification of harmful phytochemicals in various plants that can injure domestic animals and humans.

Human studies at OSU include determining the best type of dietary fat and the possible protection of vitamins C and E against oxidative stress, which is a derangement of the homeostasis of reactive oxygen species in biological systems. Ironically, oxygen and its utilization for life contribute to such pathological conditions as inflammation, atherosclerosis, aging, and age-related diseases.

Models for the study of human diseases are very useful for the development of new knowledge and new therapies. OSU is a world leader in the use of rainbow trout as a model for studies on human health. For example, results from the trout investigations have been very useful in the design of human breast cancer trials to determine the possible beneficial effects of natural anticarcinogens in certain vegetables. Obviously, OSU is an excellent home for the Linus Pauling Institute. By combining the strengths of LPI and OSU, our complementary studies will be even more effective in providing the maximum value to you, the supporters of LPI.

Last updated November, 1996