Distinguished Professor Emeritus, Linus Pauling Institute
After Dr. Frei retired as Director of the Linus Pauling Institute in 2016, he chose not to maintain an active research program. Inquires can be sent to his email address.
Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase. (2016) Redox Biol 9:220-228.
Quercetin inhibits LPS-induced adhesion molecule expression and oxidant production in human aortic endothelial cells by p38-mediated Nrf2 activation and antioxidant enzyme induction. (2016) Redox Biol 9:104-113.
Myths, artifacts, and fatal flaws: identifying limitations and opportunities in vitamin C research. (2013) Nutrients 5:5161-92.