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LPI Faculty




Régis F. Moreau, Ph.D.

Research Assistant Professor, Linus Pauling Institute

Office:119 Weniger Hall

Telephone: (541) 737-5074

Fax: (541) 737-5077

Email Address: regis.moreau@oregonstate.edu

Mailing/Express Delivery Address:
Régis F. Moreau, Ph.D.
Linus Pauling Institute
Oregon State University
571 Weniger Hall
Corvallis, OR 97331-6512


Education

1989 DEUG B, Biology and Biochemistry, University of Tours, France
1990 Licence, Organismal Biology, University of Western Brittany, Brest, France
1991 Maitrise, Oceanography. University of Western Brittany, Brest, France
1992 DEA (Diploma of Advanced Studies), Biology and Agronomy, University of Rennes 1, France
1999 Ph.D., Zoology, The Ohio State University, Columbus, Ohio

Professional Experience

1992-1993 Research Associate, IFREMER-COP, Tahiti, French Polynesia
1994-1999 Ph.D. student/Research Associate, The Ohio State University, Columbus, OH
1999-2007 Research Associate, Linus Pauling Institute, Oregon State University, Corvallis, OR
2008-present Research Assistant Professor, Linus Pauling Institute, Oregon State University, Corvallis, OR

Honors and Awards

1991-1992 Pre-doctoral Scholarship, National Research Institute in Agronomy, France
1998 Graduate Studies Alumni Research Award of The Ohio State University

Professional Activities and Memberships

Reviewer

Free Radical Biology & Medicine
Pharmacological Research
Rejuvenation Research
Journal of Comparative Physiology B
Biochemistry
Mitochondrion
Annals of Nutrition & Metabolism

Memberships

American Society for Biochemistry and Molecular Biology (ASBMB)
American Association for the Advancement of Science (AAAS)

Research Projects

Linus Pauling Institute Pilot Project (Moreau, PI)
Down Regulation of Triglyceride Synthesis by (R)-alpha-Lipoic Acid
The goal of the study is to investigate the molecular mechanism of lipoic acid's hypotriglyceridemic properties.

R01 2AG017141 (Hagen, PI; Moreau, Co-PI)
NIH/NIA
Dietary Prevention of Cardiac Mitochondrial Aging
The goal of this project is to investigate the causes and consequences of mitochondrial dyslipidosis in the aging rat heart.

Recent Publications

Monette JS, Gómez LA, Moreau R, Bemer BA, Taylor AW, Hagen TM (2010) Characteristics of the rat cardiac sphingolipid pool in two mitochondrial subpopulations. Biochem Biophys Res Commun 398:272-277.

Petersen Shay K, Moreau R, Smith EJ, Smith AR, and Hagen TM (2009) Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential. Biochim Biophys Acta 1790:1149-1160.

Butler JA, Hagen TM, and Moreau R (2009) Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and downregulating liver triacylglycerol secretion. Arch Biochem Biophys 485:63-71.

Shay K, Moreau R, Smith E, and Hagen T (2008) Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity. IUBMB Life 60:362-367.

Moreau R, Nguyen B, Doneanu CE, and Hagen TM (2005) Reversal by aminoguanidine of the age-related increase in glycoxidation and lipoxidation in the cardiovascular system of Fischer 344 rats. Biochem Pharmacol 69:29-40.

Suh JH, Moreau R, Heath SHD, and Hagen TM (2005) Dietary supplementation with (R)-alpha- lipoic acid reverses the age-related accumulation of iron and depletion of antioxidants in the rat cerebral cortex. Redox Rep 10:52-60.

Moreau R, Heath SHD, Doneanu CE, Harris RA, and Hagen TM (2004) Age-related compensatory activation of pyruvate dehydrogenase complex in rat heart. Biochem Biophys Res Comm 325:48-58.

Moreau R, Heath SHD, Doneanu CE, Lindsay JG, and Hagen TM (2003) Age-related increase in 4-hydroxynonenal adduction to rat heart alpha-ketoglutarate dehydrogenase does not cause loss of its catalytic activity. Antioxid Redox Signal 5:517-527.