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Debbie J. Mustacich, Ph.D.

Research Associate Professor, Linus Pauling Institute and
Department of Biomedical Sciences

Office: 413 Linus Pauling Science Center

Telephone: (541) 737-8730

Fax: (541) 737-5077

Email Address:

Mailing/Express Delivery Address:
Debbie J. Mustacich, Ph.D.
Linus Pauling Institute
Oregon State University
307 Linus Pauling Science Center
Corvallis, OR 97331


1978 B.A., Biology/Chemistry (minor), Central Washington University, Ellensburg, WA
1979 Medical Technology Internship, St. Joseph Hospital, Tacoma, WA
1981 Teaching Certification, University of Puget Sound, Tacoma, WA
1984-85 Organic Synthesis Research, University of Puget Sound, Tacoma, WA
1998 Ph.D., Biochemistry/Biophysics, Oregon State University, Corvallis, OR

Professional Experience

1977-78 Teaching Assistant, Biology Dept., Central Washington University, Ellensburg, WA
1979-80 Medical Technologist, Tacoma, WA
1981-88 Chemistry/Biology Teacher and Science Enrichment Program Consultant, Bellarmine Preparatory School and Tacoma/Federal Way Public Schools, WA
1991-98 Graduate Research, Biochemistry and Biophysics Dept., Oregon State University, Corvallis, OR
1995-96 Consultant for the Oxygenates Evaluation Committee, Health Effects Institute, while working on Ph.D. at OSU
1998-2003 Postdoctoral Fellow to Research Assistant Professor, Department of Pathology/Arizona Cancer Center, University of Arizona, Tucson, AZ
2003-04 Senior Scientist/Manager of Assay Development, Ventana Medical Systems, Inc., Tucson, AZ
2004-08 Research Faculty, Linus Pauling Institute, Oregon State University, Corvallis, OR
2008-14 Assistant Professor, Sr. Res., Department of Biomedical Sciences and Linus Pauling Institute, Oregon State University, Corvallis, OR
2014-present Associate Professor, Sr. Res., Department of Biomedical Sciences and Linus Pauling Institute, Oregon State University, Corvallis, OR


1978 Dean's Scholar and Phi Kappa Phi Honor Society, Central Washington University
1991-92 Molecular and Cellular Biology Research Fellowship, Oregon State University
1991-92 Graduate School Fellowship, Oregon State University
1995-97 Oregon Sports Lottery Scholarship, Oregon State University (2 awards)
1996 Society of Toxicology Travel Award
1996 Sigma Xi Honorable Mention, Oregon State University Graduate Conference
1998-99 Cancer Biology Postdoctoral Fellowship, University of Arizona
1999-2002 NIH Individual National Research Service Award (NRSA), University of Arizona
2000-01 Caldwell Fellowship, University of Arizona
2002-03 Cancer Prevention and Control Award, University of Arizona

Current Funding

Alpha Tocopherol Modulation of Xenobiotic Metabolism, NIH/NIDDK (R01 DK067930, Co-PI)

Prophylactic Use of Vitamin E for Prevention of Occupational PAH-Induced Damage, NIH/NIEHS (R21 ES015872, PI)

Vitamin E as a Potentiator of Vitamin K Inadequacy, USDA (Co-PI)

Mechanism of Cisplatin-induced Neuropathy, General Research Funds, Oregon State University (PI)

ARRA Supplement Award, NIH/NIEHS (3R21 ES015872-02S1, PI)

Professional Activities and Memberships

Society for Free Radical Biology and Medicine
International Society for Free Radical Research
Society of Toxicology

Recent Publications

Farley SM, Leonard SW, Labut EM, Raines HF, Card DJ, Harrington DJ, Mustacich DJ, Traber MG. (2012) Vitamin E decreases extra-hepatic menaquinone-4 concentrations in rats fed menadione or phylloquinone. Mol Nutr Food Res 56:912-922.

Gonzalez D, Mustacich DJ, Traber MG, Cherian G. (2011) Early feeding and dietary lipids affect broiler tissue fatty acids, vitamin E status, and cyclooxygenase-2 protein expression upon lipopolysaccharide challenge. Poult Sci 90:2790-2800.

Mustacich DJ, Leonard SW, Patel N, and Traber MG (2010) Alpha-tocopherol beta-oxidation localized to rat liver mitochondria. Free Radic Biol Med 48:73-81.

Traber MG, Mustacich DJ, Sullivan LC, Leonard SW, Ahern-Rindell A, and Kerkvliet N (2010) Vitamin E status and metabolism in adult and aged aryl hydrocarbon receptor null mice. J Nutr Biochem 21:1193-1199.

Mustacich DJ, Gohil K, Bruno RS, Yan M, Leonard SW, Cross CE, Ho E, and Traber MG (2009) Alpha-tocopherol modulates genes involved in hepatic xenobiotic pathways in mice. J Nutr Biochem 20:469-476.