Office: 413 Linus Pauling Science Center
Telephone: (541) 737-8730
Fax: (541) 737-5077
Email Address: debbie.mustacich@oregonstate.edu
Mailing/Express Delivery Address:
Debbie J. Mustacich, Ph.D.
Linus Pauling Institute
Oregon State University
307 Linus Pauling Science Center
Corvallis, OR 97331
| 1978 | B.A., Biology/Chemistry (minor), Central Washington University, Ellensburg, WA | 1979 | Medical Technology Internship, St. Joseph Hospital, Tacoma, WA | 1981 | Teaching Certification, University of Puget Sound, Tacoma, WA | 1984-85 | Organic Synthesis Research, University of Puget Sound, Tacoma, WA |
| 1998 | Ph.D., Biochemistry/Biophysics, Oregon State University, Corvallis, OR |
| 1977-78 | Teaching Assistant, Biology Dept., Central Washington University, Ellensburg, WA |
| 1979-80 | Medical Technologist, Tacoma, WA |
| 1981-88 | Chemistry/Biology Teacher and Science Enrichment Program Consultant, Bellarmine Preparatory School and Tacoma/Federal Way Public Schools, WA |
| 1991-98 | Graduate Research, Biochemistry and Biophysics Dept., Oregon State University, Corvallis, OR |
| 1995-96 | Consultant for the Oxygenates Evaluation Committee, Health Effects Institute, while working on Ph.D. at OSU |
| 1998-2003 | Postdoctoral Fellow to Research Assistant Professor, Department of Pathology/Arizona Cancer Center, University of Arizona, Tucson, AZ |
| 2003-04 | Senior Scientist/Manager of Assay Development, Ventana Medical Systems, Inc., Tucson, AZ |
| 2004-08 | Research Faculty, Linus Pauling Institute, Oregon State University, Corvallis, OR |
| 2008-present | Assistant Professor, Sr. Res., Department of Biomedical Sciences and Linus Pauling Institute, Oregon State University, Corvallis, OR |
| 1978 | Dean's Scholar and Phi Kappa Phi Honor Society, Central Washington University |
| 1991-92 | Molecular and Cellular Biology Research Fellowship, Oregon State University |
| 1991-92 | Graduate School Fellowship, Oregon State University |
| 1995-97 | Oregon Sports Lottery Scholarship, Oregon State University (2 awards) |
| 1996 | Society of Toxicology Travel Award |
| 1996 | Sigma Xi Honorable Mention, Oregon State University Graduate Conference |
| 1998-99 | Cancer Biology Postdoctoral Fellowship, University of Arizona |
| 1999-2002 | NIH Individual National Research Service Award (NRSA), University of Arizona |
| 2000-01 | Caldwell Fellowship, University of Arizona |
| 2002-03 | Cancer Prevention and Control Award, University of Arizona |
Alpha Tocopherol Modulation of Xenobiotic Metabolism, NIH/NIDDK (R01 DK067930, Co-PI)
Prophylactic Use of Vitamin E for Prevention of Occupational PAH-Induced Damage, NIH/NIEHS (R21 ES015872, PI)
Vitamin E as a Potentiator of Vitamin K Inadequacy, USDA (Co-PI)
Mechanism of Cisplatin-induced Neuropathy, General Research Funds, Oregon State University (PI)
ARRA Supplement Award, NIH/NIEHS (3R21 ES015872-02S1, PI)
Society for Free Radical Biology and Medicine
International Society for Free Radical Research
Society of Toxicology
Powis G, Mustacich D, and Coon A (2000) The role of the redox protein thioredoxin in cell growth and cancer. Free Radic Biol Med 29, 312-322.
Merwin JR, Mustacich DJ, Muller EG, Pearson GD, and Merrill GF (2002) Reporter gene transactivation by human p53 is inhibited in thioredoxin reductase null yeast by a mechanism associated with thioredoxin oxidation and independent of changes in the redox state of glutathione. Carcinogenesis 23, 1609-1615.
Mustacich DJ, Wagner A, Williams R, Bair W, Barbercheck L, Stratton SP, Bhattacharya AK, and Powis G (2004) Increased skin carcinogenesis in a keratinocyte directed thioredoxin-1 transgenic mouse. Carcinogenesis 25, 1983-1989.
Mustacich DJ, Leonard SW, Devereaux MW, Sokol RJ, and Traber MG (2006) Alpha-tocopherol regulation of hepatic cytochrome P450s and ABC transporters in rats. Free Radic Biol Med 41, 1069-1078.
Bruno RS, Song Y, Leonard SW, Mustacich DJ, Taylor AW, Traber MG, and Ho E (2007) Dietary zinc restriction in rats alters antioxidant status and increases plasma F2-isoprostanes. J Nutr Biochem 18, 509-518.
Mustacich DJ, Bruno RS, and Traber MG (2007) Vitamin E. Vitam Horm 76, 1-21. (Invited Chapter)
Leonard SW, Joss JD, Mustacich DJ, Blatt DH, Lee YS, and Traber MG (2007) Effects of vitamin E on cholesterol levels of hypercholesterolemic patients receiving statins. Am J Health Syst Pharm 64, 2257-2266.
Mustacich DJ, Vo AT, Elias VD, Payne K, Sullivan L, Leonard SW, and Traber MG (2007) Regulatory mechanisms to control tissue alpha-tocopherol. Free Radic Biol Med 43, 610-618.
Mustacich DJ, Gohil K, Bruno RS, Yan M, Leonard SW, Cross CE, Ho E, and Traber MG (2009) Alpha-tocopherol modulates genes involved in hepatic xenobiotic pathways in mice. J Nutr Biochem 20, 469-476.
Mustacich DJ, Leonard SW, Patel N, and Traber MG (2010) Alpha-tocopherol beta-oxidation localized to rat liver mitochondria. Free Radic Biol Med 48:73-81.
Traber MG, Mustacich DJ, Sullivan LC, Leonard SW, Ahern-Rindell A, and Kerkvliet N (2010) Vitamin E status and metabolism in adult and aged aryl hydrocarbon receptor null mice. J Nutr Biochem [Epub ahead of print].
