Office: 561 Weniger Hall
Telephone: (541) 737-9476
Fax: (541) 737-5077
Email Address: debbie.mustacich@oregonstate.edu
Mailing/Express Delivery Address:
Debbie J. Mustacich, Ph.D.
Linus Pauling Institute
Oregon State University
571 Weniger Hall
Corvallis, OR 97331-6512
| 1978 | B.A., Biology/Chemistry (minor), Central Washington University, Ellensburg, WA | 1979 | Medical Technology Internship, St. Joseph Hospital, Tacoma, WA | 1981 | Teaching Certification, University of Puget Sound, Tacoma, WA | 1984-85 | Organic Synthesis Research, University of Puget Sound, Tacoma, WA |
| 1998 | Ph.D., Biochemistry/Biophysics, Oregon State University, Corvallis, OR |
| 1977-78 | Teaching Assistant, Biology Dept., Central Washington University, Ellensburg, WA |
| 1979-80 | Medical Technologist, Tacoma, WA |
| 1981-88 | Chemistry/Biology Teacher and Science Enrichment Program Consultant, Bellarmine Preparatory School and Tacoma/Federal Way Public Schools, WA |
| 1991-98 | Graduate Research, Biochemistry and Biophysics Dept., Oregon State University, Corvallis, OR |
| 1995-96 | Consultant for the Oxygenates Evaluation Committee, Health Effects Institute, while working on Ph.D. at OSU |
| 1998-2003 | Postdoctoral Fellow to Research Assistant Professor, Department of Pathology/Arizona Cancer Center, University of Arizona, Tucson, AZ |
| 2003-04 | Senior Scientist/Manager of Assay Development, Ventana Medical Systems, Inc., Tucson, AZ |
| 2004-08 | Research Faculty, Linus Pauling Institute, Oregon State University, Corvallis, OR |
| 2008-present | Assistant Professor, Sr. Res., Department of Biomedical Sciences and Linus Pauling Institute, Oregon State University, Corvallis, OR |
| 1978 | Dean's Scholar and Phi Kappa Phi Honor Society, Central Washington University |
| 1991-92 | Molecular and Cellular Biology Research Fellowship, Oregon State University |
| 1991-92 | Graduate School Fellowship, Oregon State University |
| 1995-97 | Oregon Sports Lottery Scholarship, Oregon State University (2 awards) |
| 1996 | Society of Toxicology Travel Award |
| 1996 | Sigma Xi Honorable Mention, Oregon State University Graduate Conference |
| 1998-99 | Cancer Biology Postdoctoral Fellowship, University of Arizona |
| 1999-2002 | NIH Individual National Research Service Award (NRSA), University of Arizona |
| 2000-01 | Caldwell Fellowship, University of Arizona |
| 2002-03 | Cancer Prevention and Control Award, University of Arizona |
Alpha Tocopherol Modulation of Xenobiotic Metabolism, NIH/NIDDK (R01 DK067930, Co-PI)
Prophylactic Use of Vitamin E for Prevention of Occupational PAH-Induced Damage, NIH/NIEHS (R21 ES015872, PI)
Vitamin E as a Potentiator of Vitamin K Inadequacy, USDA (Co-PI)
Mechanism of Cisplatin-induced Neuropathy, General Research Funds, Oregon State University (PI)
ARRA Supplement Award, NIH/NIEHS (3R21 ES015872-02S1, PI)
Society for Free Radical Biology and Medicine
International Society for Free Radical Research
Society of Toxicology
Powis G., Mustacich D., and Coon A. (2000). The role of the redox protein thioredoxin in cell growth and cancer. Free Radic Biol Med 29, 312-322.
Merwin J.R., Mustacich D.J., Muller E.G., Pearson G.D., and Merrill G.F (2002). Reporter gene transactivation by human p53 is inhibited in thioredoxin reductase null yeast by a mechanism associated with thioredoxin oxidation and independent of changes in the redox state of glutathione. Carcinogenesis 23, 1609-1615.
Mustacich D.J., Wagner A., Williams R., Bair W., Barbercheck L., Stratton S.P., Bhattacharya A.K., and Powis G. (2004). Increased skin carcinogenesis in a keratinocyte directed thioredoxin-1 transgenic mouse. Carcinogenesis 25, 1983-1989.
Mustacich D.J., Leonard S.W., Devereaux M.W., Sokol R.J., and Traber M.G. (2006). Alpha-tocopherol regulation of hepatic cytochrome P450s and ABC transporters in rats. Free Radic Biol Med 41, 1069-1078.
Bruno R.S., Song Y., Leonard S.W., Mustacich D.J., Taylor A.W., Traber M.G., and Ho E. (2007). Dietary zinc restriction in rats alters antioxidant status and increases plasma F2-isoprostanes. J Nutr Biochem 18, 509-518.
Mustacich D.J., Bruno R.S., and Traber M.G. (2007). Vitamin E. Vitam Horm 76, 1-21. (Invited Chapter)
Leonard S.W., Joss J.D., Mustacich D.J., Blatt D.H., Lee Y.S., and Traber M.G. (2007) Effects of vitamin E on cholesterol levels of hypercholesterolemic patients receiving statins. Am J Health Syst Pharm 64, 2257-2266.
Mustacich D.J., Vo A.T., Elias V.D., Payne K., Sullivan L., Leonard S.W., and Traber M.G. (2007). Regulatory mechanisms to control tissue alpha-tocopherol. Free Radic Biol Med 43, 610-618.
Mustacich D.J., Gohil K., Bruno R.S., Yan M., Leonard S.W., Cross C.E., Ho E., and Traber M.G. (2009) Alpha-tocopherol modulates genes involved in hepatic xenobiotic pathways in mice. J Nutr Biochem 20, 469-476.
Traber M.G, Mustacich D.J., Sullivan L.C., Ahern-Rindell A., and Kerkvliet N. (2009) Vitamin E status and metabolism in aryl hydrocarbon receptor null mice. J Nutr Biochem, Accepted.
Mustacich D.J., Leonard S.W., Patel N., and Traber M.G. (2009) Alpha-tocopherol beta-oxidation localized to rat liver mitochondria. Free Radic Biol Med, Accepted.
