Office: 555A Weniger Hall
Telephone: (541) 737-5081
Fax: (541) 737-5077
Email Address: weijian.zhang@oregonstate.edu
Mailing/Express Delivery Address:
Weijian Zhang, Ph.D.
Linus Pauling Institute
Oregon State University
571 Weniger Hall
Corvallis, OR 97331-6512
| 1982 | M.D., Jishou University School of Medicine, P.R. China |
| 1987 | M.S., Beijing University of Chinese Medicine & Pharmacology (BUCMP), P. R. China |
| 1996 | Ph.D., Institute of Vascular Biology and Thrombosis Research, University of Vienna, Austria |
| 1982-1984 | Resident Physician, Dept. of Internal Medicine, Changsha No. 1. Hospital, China |
| 1987-1988 | Assistant of Physiology, Dept. of Physiology, BUCMP, China |
| 1988-1992 | Lecturer of Physiology, Dept. of Physiology, BUCMP, China |
| 1992-1996 | Postdoctoral Fellow, Institute of Vascular Biology and Thrombosis Research, University of Vienna, Austria |
| 1996-1997 | Faculty Research Associate, Division of Cell Biology, The Hospital for Sick Children, the Dept. of Surgery, Toronto Hospital, University of Toronto, Canada |
| 1997-1998 | Faculty Research Associate, Institute for Gene Therapy and Molecular Medicine, The Mount Sinai Medical Center, The Mount Sinai School of Medicine, New York University, USA |
| 1998-2001 | Faculty Research Associate, Linus Pauling Institute, Oregon State University, USA |
| 2002-present | Research Assistant Professor, Linus Pauling Institute, Oregon State University |
| 1992-present | Member of International Society for Fibrinolysis and Thrombolysis |
| 1998-present | Member of the American Association for the Advancement of Science |
| 2000-present | Member of the American Heart Association |
| 1987 | Second prize of “Excellent Scientific Research Paper”, Beijing Association of the Integration of Traditional and Western Medicine, Beijing, China |
| 1988 | Third prize of “Sun's Foundation for Medical Science Development”, The Ministry of Health, Beijing, China |
| 1988-1990 | Prize of “Excellent Scientific Research Papers”, BUCMP, Beijing, China |
| 1992-1995 | North-South Dialogue Scholarship (EH-project 894), the Austrian Academic Exchange Service, the Ministry of Education, Vienna, Austria |
| 1994 | First prize of "Highest Rated Abstract", 38th Annual Meeting of the German Society for Thrombosis and Hemostasis Research, Munich, Germany |
| 1994 | First prize of "Erwin Deutsch-Poster Award", Update in Thrombolysis Conference, Vienna, Austria |
My major research project is to investigate the role and mechanisms of action of intracellular antioxidants and metal chelators in cytokine-induced endothelial dysfuntion in vitro and in vivo, and atherosclerotic development in mouse models. The ultimate goal is to develop new, targeted strategies for the prevention and treatment of heart disease, primarily through dietary interventions.
| 1998-2000 | NIH R01 HL-56170 (Co-investigator, project 1) |
| 2000-2005 | NIH P01 HL-60886 (Co-investigator, project 1) |
| 2001-2003 | NIH R03 ES-11542 (Principal Investigator) |
| 2002-2003 | Pilot Project Program Grant (Principal Investigator), Linus Pauling Institute |
| 2003-2008 | NIH P01 AT002034 (Co-Project Leader, Project 1) |
Zhang WJ, Hufnagl P, Binder BR, and Wojta J (2003) Antiinflammatory activity of Astragaloside IV is mediated by inhibition of NF-kappaB activation and adhesion molecule expression. Thrombosis and Haemostasis 90, 904-914.
Zhang WJ and Frei B (2003) A different view on human albumin—author's reply. Cardiovascular Research 58, 723-724.
Zhang WJ and Frei B (2003) Intracellular metal ion chelators inhibit TNF-alpha-induced SP-1 activation and adhesion molecule expression in human aortic endothelial cells. Free Radical Biology & Medicine 34, 674-682.
Zhang W, Wei H, Hagen T, and Frei B (2007) Alpha-lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway. Proc. Natl. Acad. Sci. USA 104, 4077-4082.
Zhang WJ, Bird KE, McMillen TS, LeBoeuf RC, Hagen TM, and Frei B (2008) Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice. Circulation 117, 421-428.
