TitleCENSOR--a program for identification and elimination of repetitive elements from DNA sequences.
Publication TypeJournal Article
Year of Publication1996
AuthorsJurka J, Klonowski P, Dagman V, Pelton P
JournalComput Chem
Date Published1996 Mar
KeywordsAlgorithms, Base Sequence, Computer Communication Networks, Computers, Databases, Factual, Molecular Sequence Data, Repetitive Sequences, Nucleic Acid, Sequence Alignment, Sequence Analysis, Software

CENSOR is a program designed to identify and eliminate fragments of DNA sequences homologous to any chosen reference sequences, in particular to repetitive elements. CENSOR is based on two principal algorithms of Smith & Waterman (1981) [J. Mol. Biol. 147, 195] and Wilbur & Lipman (1983) [Proc. Natl. Acad. Sci. U.S.A. 80, 726]. It includes several pre-set sensitivity levels based on both biological and statistical criteria which help to distinguish between aligned pairs of homologous and non-homologous sequences. CENSOR has been implemented in C/C + + in the SUN/UNIX environment.

Alternate JournalComput. Chem.
PubMed ID8867843