Title | CENSOR--a program for identification and elimination of repetitive elements from DNA sequences. |
Publication Type | Journal Article |
Year of Publication | 1996 |
Authors | Jurka J, Klonowski P, Dagman V, Pelton P |
Journal | Comput Chem |
Volume | 20 |
Issue | 1 |
Pagination | 119-21 |
Date Published | 1996 Mar |
ISSN | 0097-8485 |
Keywords | Algorithms, Base Sequence, Computer Communication Networks, Computers, Databases, Factual, Molecular Sequence Data, Repetitive Sequences, Nucleic Acid, Sequence Alignment, Sequence Analysis, Software |
Abstract | CENSOR is a program designed to identify and eliminate fragments of DNA sequences homologous to any chosen reference sequences, in particular to repetitive elements. CENSOR is based on two principal algorithms of Smith & Waterman (1981) [J. Mol. Biol. 147, 195] and Wilbur & Lipman (1983) [Proc. Natl. Acad. Sci. U.S.A. 80, 726]. It includes several pre-set sensitivity levels based on both biological and statistical criteria which help to distinguish between aligned pairs of homologous and non-homologous sequences. CENSOR has been implemented in C/C + + in the SUN/UNIX environment. |
DOI | 10.1016/s0097-8485(96)80013-1 |
Alternate Journal | Comput. Chem. |
PubMed ID | 8867843 |