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1,2-Dimethylhydrazine
Blum CA
,
Xu M
,
Orner GA
,
G Díaz D
,
Li Q
,
Dashwood WMohaiza
,
Bailey GS
,
Dashwood RH
. 2003.
Promotion versus suppression of rat colon carcinogenesis by chlorophyllin and chlorophyll: modulation of apoptosis, cell proliferation, and beta-catenin/Tcf signaling.
.
Mutat Res. 523-524:217-23.
Blum CA
,
Tanaka T
,
Zhong X
,
Li Q
,
Dashwood W-M
,
Pereira C
,
Xu M
,
Dashwood RH
. 2003.
Mutational analysis of Ctnnb1 and Apc in tumors from rats given 1,2-dimethylhydrazine or 2-amino-3-methylimidazo[4,5-f]quinoline: mutational 'hotspots' and the relative expression of beta-catenin and c-jun.
.
Mol Carcinog. 36(4):195-203.
Xu M
,
Orner GA
,
Bailey GS
,
Stoner GD
,
Horio DT
,
Dashwood RH
. 2001.
Post-initiation effects of chlorophyllin and indole-3-carbinol in rats given 1,2-dimethylhydrazine or 2-amino-3-methyl- imidazo.
.
Carcinogenesis. 22(2):309-14.
Blum CA
,
Xu M
,
Orner GA
,
Fong AT
,
Bailey GS
,
Stoner GD
,
Horio DT
,
Dashwood RH
. 2001.
beta-Catenin mutation in rat colon tumors initiated by 1,2-dimethylhydrazine and 2-amino-3-methylimidazo[4,5-f]quinoline, and the effect of post-initiation treatment with chlorophyllin and indole-3-carbinol.
.
Carcinogenesis. 22(2):315-20.
Wang R
,
W Dashwood M
,
Bailey GS
,
Williams DE
,
Dashwood RH
. 2006.
Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in beta-catenin that are independent of beta-catenin mutation status.
.
Mutat Res. 601(1-2):11-8.
3T3-L1 Cells
Kirkwood JS
,
Miranda CL
,
Bobe G
,
Maier CS
,
Stevens JF
. 2016.
18O-Tracer Metabolomics Reveals Protein Turnover and CDP-Choline Cycle Activity in Differentiating 3T3-L1 Pre-Adipocytes.
.
PLoS One. 11(6):e0157118.
4-Hydroxycoumarins
Rubinstein I
,
van Breemen R
,
Nosal DG
,
Weinberg G
,
Hershow RC
,
Feinstein DL
. 2019.
Should Cytochrome P450 Inducers be Used to Accelerate Clearance of Brodifacoum from Poisoned Patients?
Drugs R D. 19(1):67-71.
Feinstein DL
,
Gierzal K
,
Iqbal A
,
Kalinin S
,
Ripper R
,
Lindeblad M
,
Zahkarov A
,
Lyubimov A
,
van Breemen R
,
Weinberg G
et al.
. 2019.
The relative toxicity of brodifacoum enantiomers.
.
Toxicol Lett. 306:61-65.
5' Flanking Region
Li Q
,
Dashwood W-M
,
Zhong X
,
Al-Fageeh M
,
Dashwood RH
. 2004.
Cloning of the rat beta-catenin gene (Ctnnb1) promoter and its functional analysis compared with the Catnb and CTNNB1 promoters.
.
Genomics. 83(2):231-42.
Abetalipoproteinemia
Bredefeld C
,
M Hussain M
,
Averna M
,
Black DD
,
Brin MF
,
Burnett JR
,
Charrière S
,
Cuerq C
,
Davidson NO
,
Deckelbaum RJ
et al.
. 2022.
Guidance for the diagnosis and treatment of hypolipidemia disorders.
.
J Clin Lipidol. 16(6):797-812.
Abortion, Spontaneous
Lebold KM
,
Traber MG
. 2014.
Interactions between α-tocopherol, polyunsaturated fatty acids, and lipoxygenases during embryogenesis.
.
Free Radic Biol Med. 66:13-9.
Absorptiometry, Photon
Iwaniec UT
,
Turner RT
,
Smith BJ
,
Stoecker BJ
,
Rust A
,
Zhang B
,
Vasu VT
,
Gohil K
,
Cross CE
,
Traber MG
. 2013.
Evaluation of long-term vitamin E insufficiency or excess on bone mass, density, and microarchitecture in rodents.
.
Free Radic Biol Med. 65:1209-1214.
Absorption
Traber MG
. 2013.
Mechanisms for the prevention of vitamin E excess.
.
J Lipid Res. 54(9):2295-306.
Acetates
Matsumoto S
,
Traber MG
,
Leonard SW
,
Choi J
,
Fang X
,
Maishan M
,
Wick KD
,
Jones KD
,
Calfee CS
,
Gotts JE
et al.
. 2022.
Aerosolized vitamin E acetate causes oxidative injury in mice and in alveolar macrophages.
.
Am J Physiol Lung Cell Mol Physiol. 322(6):L771-L783.
Minato Y
,
Fassio SR
,
Kirkwood JS
,
Halang P
,
Quinn MJ
,
Faulkner WJ
,
Aagesen AM
,
Steuber J
,
Stevens JF
,
Häse CC
. 2014.
Roles of the sodium-translocating NADH:quinone oxidoreductase (Na+-NQR) on vibrio cholerae metabolism, motility and osmotic stress resistance.
.
PLoS One. 9(5):e97083.
Acetophenones
Trumbull KA
,
McAllister D
,
Gandelman MM
,
Fung WY
,
Lew T
,
Brennan L
,
Lopez N
,
Morré J
,
Kalyanaraman B
,
Beckman JS
. 2012.
Diapocynin and apocynin administration fails to significantly extend survival in G93A SOD1 ALS mice.
.
Neurobiol Dis. 45(1):137-44.
Acetyl-CoA Carboxylase
Jump DB
,
Torres-Gonzalez M
,
L Olson K
. 2011.
Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation.
.
Biochem Pharmacol. 81(5):649-60.
Acetylation
Abbas A
,
J Hall A
,
Patterson WL
,
Ho E
,
Hsu A
,
Al-Mulla F
,
Georgel PT
. 2016.
Sulforaphane modulates telomerase activity via epigenetic regulation in prostate cancer cell lines.
.
Biochem Cell Biol. 94(1):71-81.
Myzak MC
,
Dashwood RH
. 2006.
Histone deacetylases as targets for dietary cancer preventive agents: lessons learned with butyrate, diallyl disulfide, and sulforaphane.
.
Curr Drug Targets. 7(4):443-52.
Rajendran P
,
Kidane AI
,
Yu T-W
,
Dashwood W-M
,
Bisson WH
,
Löhr CV
,
Ho E
,
Williams DE
,
Dashwood RH
. 2013.
HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates.
.
Epigenetics. 8(6):612-23.
Rajendran P
,
Williams DE
,
Ho E
,
Dashwood RH
. 2011.
Metabolism as a key to histone deacetylase inhibition.
.
Crit Rev Biochem Mol Biol. 46(3):181-99.
Nian H
,
Delage B
,
Pinto JT
,
Dashwood RH
. 2008.
Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter.
.
Carcinogenesis. 29(9):1816-24.
Myzak MC
,
W Dashwood M
,
Orner GA
,
Ho E
,
Dashwood RH
. 2006.
Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice.
.
FASEB J. 20(3):506-8.
Leinweber B
,
Barofsky E
,
Barofsky DF
,
Ermilov V
,
Nylin K
,
Beckman JS
. 2004.
Aggregation of ALS mutant superoxide dismutase expressed in Escherichia coli.
.
Free Radic Biol Med. 36(7):911-8.
Myzak MC
,
P Karplus A
,
Chung F-L
,
Dashwood RH
. 2004.
A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.
.
Cancer Res. 64(16):5767-74.
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