Linus Pauling Institute

Dashwood RH.  2002.  Modulation of heterocyclic amine-induced mutagenicity and carcinogenicity: an 'A-to-Z' guide to chemopreventive agents, promoters, and transgenic models.. Mutat Res. 511(2):89-112.

Nian H, Delage B, Ho E, Dashwood RH.  2009.  Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds.. Environ Mol Mutagen. 50(3):213-21.

Blum CA, Xu M, Orner GA, G Díaz D, Li Q, Dashwood WMohaiza, Bailey GS, Dashwood RH.  2003.  Promotion versus suppression of rat colon carcinogenesis by chlorophyllin and chlorophyll: modulation of apoptosis, cell proliferation, and beta-catenin/Tcf signaling.. Mutat Res. 523-524:217-23.

Xu M, Orner GA, Bailey GS, Stoner GD, Horio DT, Dashwood RH.  2001.  Post-initiation effects of chlorophyllin and indole-3-carbinol in rats given 1,2-dimethylhydrazine or 2-amino-3-methyl- imidazo.. Carcinogenesis. 22(2):309-14.

Wang R, W Dashwood M, Bailey GS, Williams DE, Dashwood RH.  2006.  Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in beta-catenin that are independent of beta-catenin mutation status.. Mutat Res. 601(1-2):11-8.

Higdon JV, Frei B.  2005.  Is there a gender difference in the effect of antioxidants on cancer risk? Br J Nutr. 94(2):139-40.

Xu M, Dashwood RH.  1999.  Chemoprevention studies of heterocyclic amine-induced colon carcinogenesis.. Cancer Lett. 143(2):179-83.

Dashwood W-M, Orner GA, Dashwood RH.  2002.  Inhibition of beta-catenin/Tcf activity by white tea, green tea, and epigallocatechin-3-gallate (EGCG): minor contribution of H(2)O(2) at physiologically relevant EGCG concentrations.. Biochem Biophys Res Commun. 296(3):584-8.

Myzak MC, Dashwood RH.  2006.  Histone deacetylases as targets for dietary cancer preventive agents: lessons learned with butyrate, diallyl disulfide, and sulforaphane.. Curr Drug Targets. 7(4):443-52.

Atwell LL, Zhang Z, Mori M, Farris P, Vetto JT, Naik AM, Oh KY, Thuillier P, Ho E, Shannon J.  2015.  Sulforaphane Bioavailability and Chemopreventive Activity in Women Scheduled for Breast Biopsy.. Cancer Prev Res (Phila). 8(12):1184-1191.

Larsen CA, Dashwood RH, Bisson WH.  2010.  Tea catechins as inhibitors of receptor tyrosine kinases: mechanistic insights and human relevance.. Pharmacol Res. 62(6):457-64.

Thomson CA, Ho E, Strom MB.  2016.  Chemopreventive properties of 3,3'-diindolylmethane in breast cancer: evidence from experimental and human studies.. Nutr Rev. 74(7):432-43.

Myzak MC, P Karplus A, Chung F-L, Dashwood RH.  2004.  A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.. Cancer Res. 64(16):5767-74.

Parasramka MA, Ho E, Williams DE, Dashwood RH.  2012.  MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals.. Mol Carcinog. 51(3):213-30.

Perera T, Young MR, Zhang Z, Murphy G, Colburn NH, Lanza E, Hartman TJ, Cross AJ, Bobe G.  2015.  Identification and monitoring of metabolite markers of dry bean consumption in parallel human and mouse studies.. Mol Nutr Food Res. 59(4):795-806.

Stevens JF, Page JE.  2004.  Xanthohumol and related prenylflavonoids from hops and beer: to your good health!. Phytochemistry. 65(10):1317-30.

G Díaz D, Li Q, Dashwood RH.  2003.  Caspase-8 and apoptosis-inducing factor mediate a cytochrome c-independent pathway of apoptosis in human colon cancer cells induced by the dietary phytochemical chlorophyllin.. Cancer Res. 63(6):1254-61.

Dashwood RH, Ho E.  2008.  Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates.. Nutr Rev. 66 Suppl 1:S36-8.

Orner GA, Dashwood W-M, Dashwood RH.  2004.  Tumor-suppressing effects of antioxidants from tea.. J Nutr. 134(11):3177S-3178S.

Johnson GS, Li J, Beaver LM, W Dashwood M, Sun D, Rajendran P, Williams DE, Ho E, Dashwood RH.  2017.  A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a coactivator of NQO1 in sulforaphane-treated colon cancer cells.. Mol Nutr Food Res. 61(4)

Williams DE, Katchamar S, Larsen-Su SA, Stresser DM, Dehal SS, Kupfer D.  2001.  Concurrent flavin-containing monooxygenase down regulation and cytochrome P450 induction by dietary indoles in the rat: implication for drug-drug interactions.. Adv Exp Med Biol. 500:635-8.

Feinstein DL, Gierzal K, Iqbal A, Kalinin S, Ripper R, Lindeblad M, Zahkarov A, Lyubimov A, van Breemen R, Weinberg G et al..  2019.  The relative toxicity of brodifacoum enantiomers.. Toxicol Lett. 306:61-65.

Rubinstein I, van Breemen R, Nosal DG, Weinberg G, Hershow RC, Feinstein DL.  2019.  Should Cytochrome P450 Inducers be Used to Accelerate Clearance of Brodifacoum from Poisoned Patients? Drugs R D. 19(1):67-71.

Branson JA, McLean DJ, Forsberg NE, Bobe G.  2016.  Yeast-containing feed additive alters gene expression profiles associated with innate immunity in whole blood of a rodent model.. Innate Immun. 22(4):249-56.

Kovacs M, Trias E, Varela V, Ibarburu S, Beckman JS, Moura IC, Hermine O, King PH, Si Y, Kwon Y et al..  2019.  CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS.. Int J Mol Sci. 20(16)