Found 7033 results
Author [ Keyword(Desc)] Title Type Year
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Aging
Suh JH, Shigeno ET, Morrow JD, Cox B, Rocha AE, Frei B, Hagen TM.  2001.  Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)-(alpha)-lipoic acid.. FASEB J. 15(3):700-6.
Smith AR, Hagen TM.  2003.  Vascular endothelial dysfunction in aging: loss of Akt-dependent endothelial nitric oxide synthase phosphorylation and partial restoration by (R)-alpha-lipoic acid.. Biochem Soc Trans. 31(Pt 6):1447-9.
Wang R, Yu Z, Sunchu B, Shoaf J, Dang I, Zhao S, Caples K, Bradley L, Beaver LM, Ho E et al..  2017.  Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2-independent mechanism.. Aging Cell. 16(3):564-574.
Blumberg JB, Frei B, Fulgoni VL, Weaver CM, Zeisel SH.  2017.  Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups.. Nutrients. 9(12)
Wong CP, Rinaldi NA, Ho E.  2015.  Zinc deficiency enhanced inflammatory response by increasing immune cell activation and inducing IL6 promoter demethylation.. Mol Nutr Food Res. 59(5):991-9.
Smith AR, Visioli F, Frei B, Hagen TM.  2006.  Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A.. Aging Cell. 5(5):391-400.
Smith EJ, Shay KP, Thomas NO, Butler JA, Finlay LF, Hagen TM.  2015.  Age-related loss of hepatic Nrf2 protein homeostasis: Potential role for heightened expression of miR-146a.. Free Radic Biol Med. 89:1184-91.
Loza AMárquez, Elias V, Wong CP, Ho E, Bermudez M, Magnusson KR.  2017.  Effects of ibuprofen on cognition and NMDA receptor subunit expression across aging.. Neuroscience. 344:276-292.
Zamzow DR, Elias V, Legette LCL, Choi J, J Stevens F, Magnusson KR.  2014.  Xanthohumol improved cognitive flexibility in young mice.. Behav Brain Res. 275:1-10.
Shay KPetersen, Hagen TM.  2009.  Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A.. Biogerontology. 10(4):443-56.
Smith AR, Visioli F, Hagen TM.  2006.  Plasma membrane-associated endothelial nitric oxide synthase and activity in aging rat aortic vascular endothelia markedly decline with age.. Arch Biochem Biophys. 454(1):100-5.
Fleming JE, Reveillaud I, Niedzwiecki A.  1992.  Role of oxidative stress in Drosophila aging.. Mutat Res. 275(3-6):267-79.
Finlay LA, Michels AJ, Butler JA, Smith EJ, Monette JS, Moreau RF, Petersen SKate, Frei B, Hagen TM.  2012.  R-α-lipoic acid does not reverse hepatic inflammation of aging, but lowers lipid anabolism, while accentuating circadian rhythm transcript profiles.. Am J Physiol Regul Integr Comp Physiol. 302(5):R587-97.
Alanine Transaminase
Netke SP, Roomi MW, Tsao C, Niedzwiecki A.  1997.  Ascorbic acid protects guinea pigs from acute aflatoxin toxicity.. Toxicol Appl Pharmacol. 143(2):429-35.
Aldehydes
Miranda CL, Reed RL, Kuiper HC, Alber S, Stevens JF.  2009.  Ascorbic acid promotes detoxification and elimination of 4-hydroxy-2(E)-nonenal in human monocytic THP-1 cells.. Chem Res Toxicol. 22(5):863-74.
Suh JH, Heath S-H, Hagen TM.  2003.  Two subpopulations of mitochondria in the aging rat heart display heterogenous levels of oxidative stress.. Free Radic Biol Med. 35(9):1064-72.
Kuiper HC, Bruno RS, Traber MG, Stevens JF.  2011.  Vitamin C supplementation lowers urinary levels of 4-hydroperoxy-2-nonenal metabolites in humans.. Free Radic Biol Med. 50(7):848-53.
Moreau R, Heath S-HD, Doneanu CE, J Lindsay G, Hagen TM.  2003.  Age-related increase in 4-hydroxynonenal adduction to rat heart alpha-ketoglutarate dehydrogenase does not cause loss of its catalytic activity.. Antioxid Redox Signal. 5(5):517-27.
Sowell J, Frei B, Stevens JF.  2004.  Vitamin C conjugates of genotoxic lipid peroxidation products: structural characterization and detection in human plasma.. Proc Natl Acad Sci U S A. 101(52):17964-9.
Kuiper HC, Langsdorf BL, Miranda CL, Joss J, Jubert C, Mata JE, Stevens JF.  2010.  Quantitation of mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites in a smoking cessation study.. Free Radic Biol Med. 48(1):65-72.
Kuiper HC, Miranda CL, Sowell JD, Stevens JF.  2008.  Mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites are in vivo markers of oxidative stress.. J Biol Chem. 283(25):17131-8.

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