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Biblio
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Antioxidants
Mastaloudis A
,
Yu T-W
,
O'Donnell RP
,
Frei B
,
Dashwood RH
,
Traber MG
. 2004.
Endurance exercise results in DNA damage as detected by the comet assay.
.
Free Radic Biol Med. 36(8):966-75.
Apoptosis
Kopparapu PR
,
Pearce MC
,
Löhr CV
,
Duong C
,
Jang HSang
,
Tyavanagimatt S
,
O'Donnell EF
,
Nakshatri H
,
Kolluri SK
. 2024.
Identification and Characterization of a Small Molecule Bcl-2 Functional Converter.
.
Cancer Res Commun. 4(3):634-644.
Blum CA
,
Xu M
,
Orner GA
,
G Díaz D
,
Li Q
,
Dashwood WMohaiza
,
Bailey GS
,
Dashwood RH
. 2003.
Promotion versus suppression of rat colon carcinogenesis by chlorophyllin and chlorophyll: modulation of apoptosis, cell proliferation, and beta-catenin/Tcf signaling.
.
Mutat Res. 523-524:217-23.
Apoptosis Regulatory Proteins
Kopparapu PR
,
Pearce MC
,
Löhr CV
,
Duong C
,
Jang HSang
,
Tyavanagimatt S
,
O'Donnell EF
,
Nakshatri H
,
Kolluri SK
. 2024.
Identification and Characterization of a Small Molecule Bcl-2 Functional Converter.
.
Cancer Res Commun. 4(3):634-644.
Ascorbic Acid
Roomi MW
,
Ogg M
,
Tsao CS
,
Gibson GG
. 1997.
Ascorbic acid deficiency decreases the expression of CYP4A1 in liver microsomes of guinea pigs.
.
Res Commun Mol Pathol Pharmacol. 95(1):3-10.
Ascorbic Acid Deficiency
Roomi MW
,
Ogg M
,
Tsao CS
,
Gibson GG
. 1997.
Ascorbic acid deficiency decreases the expression of CYP4A1 in liver microsomes of guinea pigs.
.
Res Commun Mol Pathol Pharmacol. 95(1):3-10.
Atherosclerosis
Okamoto R
,
Gery S
,
Gombart AF
,
Wang X
,
Castellani LW
,
Akagi T
,
Chen S
,
Arditi M
,
Ho Q
,
Lusis AJ
et al.
. 2014.
Deficiency of CCAAT/enhancer binding protein-epsilon reduces atherosclerotic lesions in LDLR-/- mice.
.
PLoS One. 9(1):e85341.
Benzo(a)pyrene
Maier MLVermilli
,
Siddens LK
,
Pennington JM
,
Uesugi SL
,
Labut EM
,
Vertel EA
,
Anderson KA
,
Tidwell LG
,
Tilton SC
,
Ognibene TJ
et al.
. 2023.
Impact of phenanthrene co-administration on the toxicokinetics of benzo[a]pyrene in humans. UPLC-accelerator mass spectrometry following oral microdosing.
.
Chem Biol Interact. 382:110608.
Maier MLVermilli
,
Siddens LK
,
Pennington JM
,
Uesugi SL
,
Anderson KA
,
Tidwell LG
,
Tilton SC
,
Ognibene TJ
,
Turteltaub KW
,
Smith JN
et al.
. 2022.
Benzo[a]pyrene (BaP) metabolites predominant in human plasma following escalating oral micro-dosing with [C]-BaP.
.
Environ Int. 159:107045.
Hummel JM
,
Madeen EP
,
Siddens LK
,
Uesugi SL
,
McQuistan T
,
Anderson KA
,
Turteltaub KW
,
Ognibene TJ
,
Bench G
,
Krueger SK
et al.
. 2018.
Pharmacokinetics of [C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction.
.
Food Chem Toxicol. 115:136-147.
Maier MLVermilli
,
Siddens LK
,
Pennington JM
,
Uesugi SL
,
Tilton SC
,
Vertel EA
,
Anderson KA
,
Tidwell LG
,
Ognibene TJ
,
Turteltaub KW
et al.
. 2023.
Benzo[a]pyrene toxicokinetics in humans following dietary supplementation with 3,3'-diindolylmethane (DIM) or Brussels sprouts.
.
Toxicol Appl Pharmacol. 460:116377.
Benzopyrenes
Bailey GS
,
Reddy AP
,
Pereira CB
,
Harttig U
,
Baird W
,
Spitsbergen JM
,
Hendricks JD
,
Orner GA
,
Williams DE
,
Swenberg JA
. 2009.
Nonlinear cancer response at ultralow dose: a 40800-animal ED(001) tumor and biomarker study.
.
Chem Res Toxicol. 22(7):1264-76.
beta Catenin
Blum CA
,
Xu M
,
Orner GA
,
Fong AT
,
Bailey GS
,
Stoner GD
,
Horio DT
,
Dashwood RH
. 2001.
beta-Catenin mutation in rat colon tumors initiated by 1,2-dimethylhydrazine and 2-amino-3-methylimidazo[4,5-f]quinoline, and the effect of post-initiation treatment with chlorophyllin and indole-3-carbinol.
.
Carcinogenesis. 22(2):315-20.
Orner GA
,
Dashwood W-M
,
Dashwood RH
. 2004.
Tumor-suppressing effects of antioxidants from tea.
.
J Nutr. 134(11):3177S-3178S.
Dashwood W-M
,
Orner GA
,
Dashwood RH
. 2002.
Inhibition of beta-catenin/Tcf activity by white tea, green tea, and epigallocatechin-3-gallate (EGCG): minor contribution of H(2)O(2) at physiologically relevant EGCG concentrations.
.
Biochem Biophys Res Commun. 296(3):584-8.
Orner GA
,
Dashwood W-M
,
Blum CA
,
G Díaz D
,
Li Q
,
Dashwood RH
. 2003.
Suppression of tumorigenesis in the Apc(min) mouse: down-regulation of beta-catenin signaling by a combination of tea plus sulindac.
.
Carcinogenesis. 24(2):263-7.
Orner GA
,
Dashwood W-M
,
Blum CA
,
G Díaz D
,
Li Q
,
Al-Fageeh M
,
Tebbutt N
,
Heath JK
,
Ernst M
,
Dashwood RH
. 2002.
Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
.
Mutat Res. 506-507:121-7.
Blum CA
,
Xu M
,
Orner GA
,
G Díaz D
,
Li Q
,
Dashwood WMohaiza
,
Bailey GS
,
Dashwood RH
. 2003.
Promotion versus suppression of rat colon carcinogenesis by chlorophyllin and chlorophyll: modulation of apoptosis, cell proliferation, and beta-catenin/Tcf signaling.
.
Mutat Res. 523-524:217-23.
Biological Availability
Atwell LL
,
Zhang Z
,
Mori M
,
Farris P
,
Vetto JT
,
Naik AM
,
Oh KY
,
Thuillier P
,
Ho E
,
Shannon J
. 2015.
Sulforaphane Bioavailability and Chemopreventive Activity in Women Scheduled for Breast Biopsy.
.
Cancer Prev Res (Phila). 8(12):1184-1191.
Biomarkers, Tumor
Bailey GS
,
Reddy AP
,
Pereira CB
,
Harttig U
,
Baird W
,
Spitsbergen JM
,
Hendricks JD
,
Orner GA
,
Williams DE
,
Swenberg JA
. 2009.
Nonlinear cancer response at ultralow dose: a 40800-animal ED(001) tumor and biomarker study.
.
Chem Res Toxicol. 22(7):1264-76.
Atwell LL
,
Zhang Z
,
Mori M
,
Farris P
,
Vetto JT
,
Naik AM
,
Oh KY
,
Thuillier P
,
Ho E
,
Shannon J
. 2015.
Sulforaphane Bioavailability and Chemopreventive Activity in Women Scheduled for Breast Biopsy.
.
Cancer Prev Res (Phila). 8(12):1184-1191.
Body Weight
Mastaloudis A
,
Yu T-W
,
O'Donnell RP
,
Frei B
,
Dashwood RH
,
Traber MG
. 2004.
Endurance exercise results in DNA damage as detected by the comet assay.
.
Free Radic Biol Med. 36(8):966-75.
Bone and Bones
Martin SA
,
Riordan RT
,
Wang R
,
Yu Z
,
Aguirre-Burk AM
,
Wong CP
,
Olson DA
,
Branscum AJ
,
Turner RT
,
Iwaniec UT
et al.
. 2021.
Rapamycin impairs bone accrual in young adult mice independent of Nrf2.
.
Exp Gerontol. 154:111516.
Bone Density
Beaver LM
,
Song Y
,
Philbrick KA
,
Wong CP
,
Olson DA
,
Branscum AJ
,
Turner RT
,
Ho E
,
Iwaniec UT
. 2023.
Severe Zinc Deficiency Impairs Accrual of Bone in Rapidly Growing Rats That Is Partially Corrected Following Short-term Zinc Repletion.
.
Biol Trace Elem Res. 201(8):3834-3849.
Martin SA
,
Riordan RT
,
Wang R
,
Yu Z
,
Aguirre-Burk AM
,
Wong CP
,
Olson DA
,
Branscum AJ
,
Turner RT
,
Iwaniec UT
et al.
. 2021.
Rapamycin impairs bone accrual in young adult mice independent of Nrf2.
.
Exp Gerontol. 154:111516.
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