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About the LPI
Faculty and Staff
Our Research
Micronutrient Information
Publications
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Biblio
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Tandem Mass Spectrometry
Shaw JB
,
Cooper-Shepherd DA
,
Hewitt D
,
Wildgoose JL
,
Beckman JS
,
Langridge JI
,
Voinov VG
. 2022.
Enhanced Top-Down Protein Characterization with Electron Capture Dissociation and Cyclic Ion Mobility Spectrometry.
.
Anal Chem. 94(9):3888-3896.
Shaw JB
,
Malhan N
,
Vasil'ev YV
,
Lopez NI
,
Makarov A
,
Beckman JS
,
Voinov VG
. 2018.
Sequencing Grade Tandem Mass Spectrometry for Top-Down Proteomics Using Hybrid Electron Capture Dissociation Methods in a Benchtop Orbitrap Mass Spectrometer.
.
Anal Chem. 90(18):10819-10827.
Mukherjee S
,
Kapp EA
,
Lothian A
,
Roberts AM
,
Vasil'ev YV
,
Boughton BA
,
Barnham KJ
,
W Kok M
,
Hutton CA
,
Masters CL
et al.
. 2017.
Characterization and Identification of Dityrosine Cross-Linked Peptides Using Tandem Mass Spectrometry.
.
Anal Chem. 89(11):6136-6145.
Fort KL
,
Cramer CN
,
Voinov VG
,
Vasil'ev YV
,
Lopez NI
,
Beckman JS
,
Heck AJR
. 2018.
Exploring ECD on a Benchtop Q Exactive Orbitrap Mass Spectrometer.
.
J Proteome Res. 17(2):926-933.
Thiazoles
Trias E
,
Ibarburu S
,
Barreto-Núñez R
,
Babdor J
,
Maciel TT
,
Guillo M
,
Gros L
,
Dubreuil P
,
Díaz-Amarilla P
,
Cassina P
et al.
. 2016.
Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis.
.
J Neuroinflammation. 13(1):177.
Thiosemicarbazones
Hilton JB
,
Mercer SW
,
Lim NKH
,
Faux NG
,
Buncic G
,
Beckman JS
,
Roberts BR
,
Donnelly PS
,
White AR
,
Crouch PJ
. 2017.
Cu(atsm) improves the neurological phenotype and survival of SOD1 mice and selectively increases enzymatically active SOD1 in the spinal cord.
.
Sci Rep. 7:42292.
Hilton JBW
,
Kysenius K
,
Liddell JR
,
Mercer SW
,
Paul B
,
Beckman JS
,
McLean CA
,
White AR
,
Donnelly PS
,
Bush AI
et al.
. 2024.
Evidence for disrupted copper availability in human spinal cord supports Cu(atsm) as a treatment option for sporadic cases of ALS.
.
Sci Rep. 14(1):5929.
Time Factors
Ermilova IP
,
Ermilov VB
,
Levy M
,
Ho E
,
Pereira C
,
Beckman JS
. 2005.
Protection by dietary zinc in ALS mutant G93A SOD transgenic mice.
.
Neurosci Lett. 379(1):42-6.
Tissue Extracts
Hilton JB
,
Mercer SW
,
Lim NKH
,
Faux NG
,
Buncic G
,
Beckman JS
,
Roberts BR
,
Donnelly PS
,
White AR
,
Crouch PJ
. 2017.
Cu(atsm) improves the neurological phenotype and survival of SOD1 mice and selectively increases enzymatically active SOD1 in the spinal cord.
.
Sci Rep. 7:42292.
Transcription Factor AP-1
Wei H
,
Frei B
,
Beckman JS
,
Zhang W-J
. 2011.
Copper chelation by tetrathiomolybdate inhibits lipopolysaccharide-induced inflammatory responses in vivo.
.
Am J Physiol Heart Circ Physiol. 301(3):H712-20.
Treatment Outcome
Trumbull KA
,
McAllister D
,
Gandelman MM
,
Fung WY
,
Lew T
,
Brennan L
,
Lopez N
,
Morré J
,
Kalyanaraman B
,
Beckman JS
. 2012.
Diapocynin and apocynin administration fails to significantly extend survival in G93A SOD1 ALS mice.
.
Neurobiol Dis. 45(1):137-44.
Tumor Necrosis Factor-alpha
Wei H
,
Frei B
,
Beckman JS
,
Zhang W-J
. 2011.
Copper chelation by tetrathiomolybdate inhibits lipopolysaccharide-induced inflammatory responses in vivo.
.
Am J Physiol Heart Circ Physiol. 301(3):H712-20.
Tyrosine
Mukherjee S
,
Kapp EA
,
Lothian A
,
Roberts AM
,
Vasil'ev YV
,
Boughton BA
,
Barnham KJ
,
W Kok M
,
Hutton CA
,
Masters CL
et al.
. 2017.
Characterization and Identification of Dityrosine Cross-Linked Peptides Using Tandem Mass Spectrometry.
.
Anal Chem. 89(11):6136-6145.
Beckman JS
. 2002.
Protein tyrosine nitration and peroxynitrite.
.
FASEB J. 16(9):1144.
Beckman JS
. 2009.
Understanding peroxynitrite biochemistry and its potential for treating human diseases.
.
Arch Biochem Biophys. 484(2):114-6.
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