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Faculty and Staff
Our Research
Micronutrient Information
Publications
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Biblio
Found 23 results
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Hagen, Tory M
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2023
Michels AJ
,
Butler JA
,
Uesugi SL
,
Lee K
,
Frei BB
,
Bobe G
,
Magnusson KR
,
Hagen TM
. 2023.
Multivitamin/Multimineral Supplementation Prevents or Reverses Decline in Vitamin Biomarkers and Cellular Energy Metabolism in Healthy Older Men: A Randomized, Double-Blind, Placebo-Controlled Study.
.
Nutrients. 15(12)
2022
Visioli F
,
Ingram A
,
Beckman JS
,
Magnusson KR
,
Hagen TM
. 2022.
Strategies to protect against age-related mitochondrial decay: Do natural products and their derivatives help?
Free Radic Biol Med. 178:330-346.
2016
Thomas NO
,
Shay KP
,
Kelley AR
,
Butler JA
,
Hagen TM
. 2016.
Glutathione maintenance mitigates age-related susceptibility to redox cycling agents.
.
Redox Biol. 10:45-52.
2015
Smith EJ
,
Shay KP
,
Thomas NO
,
Butler JA
,
Finlay LF
,
Hagen TM
. 2015.
Age-related loss of hepatic Nrf2 protein homeostasis: Potential role for heightened expression of miR-146a.
.
Free Radic Biol Med. 89:1184-91.
Smith EJ
,
Shay KP
,
Thomas NO
,
Butler JA
,
Finlay LF
,
Hagen TM
. 2015.
Age-related loss of hepatic Nrf2 protein homeostasis: Potential role for heightened expression of miR-146a.
.
Free Radic Biol Med. 89:1184-91.
2013
Michels AJ
,
Hagen TM
,
Frei B
. 2013.
Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme function.
.
Annu Rev Nutr. 33:45-70.
Michels AJ
,
Hagen TM
,
Frei B
. 2013.
Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme function.
.
Annu Rev Nutr. 33:45-70.
2012
Keith DJ
,
Butler JA
,
Bemer B
,
Dixon B
,
Johnson S
,
Garrard M
,
Sudakin DL
,
J Christensen M
,
Pereira C
,
Hagen TM
. 2012.
Age and gender dependent bioavailability of R- and R,S-α-lipoic acid: a pilot study.
.
Pharmacol Res. 66(3):199-206.
Gómez LA
,
Hagen TM
. 2012.
Age-related decline in mitochondrial bioenergetics: does supercomplex destabilization determine lower oxidative capacity and higher superoxide production?
Semin Cell Dev Biol. 23(7):758-67.
Shay KPetersen
,
Michels AJ
,
Li W
,
Kong A-NTony
,
Hagen TM
. 2012.
Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response.
.
Biochim Biophys Acta. 1823(6):1102-9.
Shay KPetersen
,
Michels AJ
,
Li W
,
Kong A-NTony
,
Hagen TM
. 2012.
Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response.
.
Biochim Biophys Acta. 1823(6):1102-9.
Finlay LA
,
Michels AJ
,
Butler JA
,
Smith EJ
,
Monette JS
,
Moreau RF
,
Petersen SKate
,
Frei B
,
Hagen TM
. 2012.
R-α-lipoic acid does not reverse hepatic inflammation of aging, but lowers lipid anabolism, while accentuating circadian rhythm transcript profiles.
.
Am J Physiol Regul Integr Comp Physiol. 302(5):R587-97.
2010
Shay KPetersen
,
Smith EJ
,
Hagen TM
. 2010.
Transcription factor Nrf2: examination of nuclear protein levels by immunoblotting and promoter response element binding by chromatin immunoprecipitation (ChIP).
.
Curr Protoc Toxicol. Chapter 17:Unit17.13.
2009
Shay KPetersen
,
Hagen TM
. 2009.
Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A.
.
Biogerontology. 10(4):443-56.
Shay KPetersen
,
Moreau RF
,
Smith EJ
,
Smith AR
,
Hagen TM
. 2009.
Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential.
.
Biochim Biophys Acta. 1790(10):1149-60.
Shay KPetersen
,
Moreau RF
,
Smith EJ
,
Smith AR
,
Hagen TM
. 2009.
Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential.
.
Biochim Biophys Acta. 1790(10):1149-60.
Butler JA
,
Hagen TM
,
Moreau R
. 2009.
Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and downregulating liver triacylglycerol secretion.
.
Arch Biochem Biophys. 485(1):63-71.
Shenvi SV
,
Smith EJ
,
Hagen TM
. 2009.
Transcriptional regulation of rat gamma-glutamate cysteine ligase catalytic subunit gene is mediated through a distal antioxidant response element.
.
Pharmacol Res. 60(4):229-36.
2008
Shay KPetersen
,
Moreau RF
,
Smith EJ
,
Hagen TM
. 2008.
Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity.
IUBMB Life. 60(6):362-7.
2003
Michels AJ
,
Joisher N
,
Hagen TM
. 2003.
Age-related decline of sodium-dependent ascorbic acid transport in isolated rat hepatocytes.
.
Arch Biochem Biophys. 410(1):112-20.
2002
Hagen TM
,
Liu J
,
Lykkesfeldt J
,
Wehr CM
,
Ingersoll RT
,
Vinarsky V
,
Bartholomew JC
,
Ames BN
. 2002.
Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress.
.
Proc Natl Acad Sci U S A. 99(4):1870-5.
Hagen TM
,
Moreau R
,
Suh JH
,
Visioli F
. 2002.
Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid.
.
Ann N Y Acad Sci. 959:491-507.
Smith AR
,
Visioli F
,
Hagen TM
. 2002.
Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid.
.
FASEB J. 16(9):1102-4.
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