Found 443 results
Author [ Keyword(Desc)] Title Type Year
Filters: Author is Hagen, Tory M  [Clear All Filters]
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Apolipoproteins E
Zhang W-J, Bird KE, McMillen TS, Leboeuf RC, Hagen TM, Frei B.  2008.  Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice.. Circulation. 117(3):421-8.
Apoptosis
Hagen TM, Moreau R, Suh JH, Visioli F.  2002.  Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid.. Ann N Y Acad Sci. 959:491-507.
ARNTL Transcription Factors
Finlay LA, Michels AJ, Butler JA, Smith EJ, Monette JS, Moreau RF, Petersen SKate, Frei B, Hagen TM.  2012.  R-α-lipoic acid does not reverse hepatic inflammation of aging, but lowers lipid anabolism, while accentuating circadian rhythm transcript profiles.. Am J Physiol Regul Integr Comp Physiol. 302(5):R587-97.
Ascorbic Acid
Hagen TM, Liu J, Lykkesfeldt J, Wehr CM, Ingersoll RT, Vinarsky V, Bartholomew JC, Ames BN.  2002.  Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress.. Proc Natl Acad Sci U S A. 99(4):1870-5.
Michels AJ, Hagen TM, Frei B.  2013.  Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme function.. Annu Rev Nutr. 33:45-70.
Smith AR, Visioli F, Hagen TM.  2002.  Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid.. FASEB J. 16(9):1102-4.
Hagen TM, Moreau R, Suh JH, Visioli F.  2002.  Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid.. Ann N Y Acad Sci. 959:491-507.
Michels AJ, Joisher N, Hagen TM.  2003.  Age-related decline of sodium-dependent ascorbic acid transport in isolated rat hepatocytes.. Arch Biochem Biophys. 410(1):112-20.
Atherosclerosis
Zhang W-J, Bird KE, McMillen TS, Leboeuf RC, Hagen TM, Frei B.  2008.  Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice.. Circulation. 117(3):421-8.
Base Sequence
Shenvi SV, Smith EJ, Hagen TM.  2009.  Transcriptional regulation of rat gamma-glutamate cysteine ligase catalytic subunit gene is mediated through a distal antioxidant response element.. Pharmacol Res. 60(4):229-36.
Shay KPetersen, Michels AJ, Li W, Kong A-NTony, Hagen TM.  2012.  Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response.. Biochim Biophys Acta. 1823(6):1102-9.
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Butler JA, Hagen TM, Moreau R.  2009.  Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and downregulating liver triacylglycerol secretion.. Arch Biochem Biophys. 485(1):63-71.
Biological Availability
Keith DJ, Butler JA, Bemer B, Dixon B, Johnson S, Garrard M, Sudakin DL, J Christensen M, Pereira C, Hagen TM.  2012.  Age and gender dependent bioavailability of R- and R,S-α-lipoic acid: a pilot study.. Pharmacol Res. 66(3):199-206.
Biological Transport
Michels AJ, Joisher N, Hagen TM.  2003.  Age-related decline of sodium-dependent ascorbic acid transport in isolated rat hepatocytes.. Arch Biochem Biophys. 410(1):112-20.
Michels AJ, Hagen TM, Frei B.  2013.  Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme function.. Annu Rev Nutr. 33:45-70.
Blotting, Western
Moreau R, Heath S-HD, Doneanu CE, J Lindsay G, Hagen TM.  2003.  Age-related increase in 4-hydroxynonenal adduction to rat heart alpha-ketoglutarate dehydrogenase does not cause loss of its catalytic activity.. Antioxid Redox Signal. 5(5):517-27.
Shay KPetersen, Smith EJ, Hagen TM.  2010.  Transcription factor Nrf2: examination of nuclear protein levels by immunoblotting and promoter response element binding by chromatin immunoprecipitation (ChIP).. Curr Protoc Toxicol. Chapter 17:Unit17.13.
Body Weight
Zhang W-J, Bird KE, McMillen TS, Leboeuf RC, Hagen TM, Frei B.  2008.  Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice.. Circulation. 117(3):421-8.
Brain
Suh JH, Moreau R, Heath S-HD, Hagen TM.  2005.  Dietary supplementation with (R)-alpha-lipoic acid reverses the age-related accumulation of iron and depletion of antioxidants in the rat cerebral cortex.. Redox Rep. 10(1):52-60.
Cardiovascular System
Moreau R, Nguyen BT, Doneanu CE, Hagen TM.  2005.  Reversal by aminoguanidine of the age-related increase in glycoxidation and lipoxidation in the cardiovascular system of Fischer 344 rats.. Biochem Pharmacol. 69(1):29-40.
Carnitine
Gómez LA, Heath S-HD, Hagen TM.  2012.  Acetyl-L-carnitine supplementation reverses the age-related decline in carnitine palmitoyltransferase 1 (CPT1) activity in interfibrillar mitochondria without changing the L-carnitine content in the rat heart.. Mech Ageing Dev. 133(2-3):99-106.
Carnitine O-Palmitoyltransferase
Gómez LA, Heath S-HD, Hagen TM.  2012.  Acetyl-L-carnitine supplementation reverses the age-related decline in carnitine palmitoyltransferase 1 (CPT1) activity in interfibrillar mitochondria without changing the L-carnitine content in the rat heart.. Mech Ageing Dev. 133(2-3):99-106.
Catalysis
Moreau R, Heath S-HD, Doneanu CE, J Lindsay G, Hagen TM.  2003.  Age-related increase in 4-hydroxynonenal adduction to rat heart alpha-ketoglutarate dehydrogenase does not cause loss of its catalytic activity.. Antioxid Redox Signal. 5(5):517-27.
Cell Compartmentation
Shay KPetersen, Michels AJ, Li W, Kong A-NTony, Hagen TM.  2012.  Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response.. Biochim Biophys Acta. 1823(6):1102-9.
Cell Culture Techniques
Smith AR, Visioli F, Hagen TM.  2002.  Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid.. FASEB J. 16(9):1102-4.

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