Found 35 results
Author Keyword Title [ Type(Asc)] Year
Filters: Author is Hagen, Tory M  [Clear All Filters]
Journal Article
Smith AR, Visioli F, Hagen TM.  2002.  Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid.. FASEB J. 16(9):1102-4.
Li L, Smith A, Hagen TM, Frei B.  2010.  Vascular oxidative stress and inflammation increase with age: ameliorating effects of alpha-lipoic acid supplementation.. Ann N Y Acad Sci. 1203:151-9.
Suh JH, Heath S-H, Hagen TM.  2003.  Two subpopulations of mitochondria in the aging rat heart display heterogenous levels of oxidative stress.. Free Radic Biol Med. 35(9):1064-72.
Shenvi SV, Smith EJ, Hagen TM.  2009.  Transcriptional regulation of rat gamma-glutamate cysteine ligase catalytic subunit gene is mediated through a distal antioxidant response element.. Pharmacol Res. 60(4):229-36.
Shay KPetersen, Smith EJ, Hagen TM.  2010.  Transcription factor Nrf2: examination of nuclear protein levels by immunoblotting and promoter response element binding by chromatin immunoprecipitation (ChIP).. Curr Protoc Toxicol. Chapter 17:Unit17.13.
Robinson KM, Janes MS, Pehar M, Monette JS, Ross MF, Hagen TM, Murphy MP, Beckman JS.  2006.  Selective fluorescent imaging of superoxide in vivo using ethidium-based probes.. Proc Natl Acad Sci U S A. 103(41):15038-43.
Finlay LA, Michels AJ, Butler JA, Smith EJ, Monette JS, Moreau RF, Petersen SKate, Frei B, Hagen TM.  2012.  R-α-lipoic acid does not reverse hepatic inflammation of aging, but lowers lipid anabolism, while accentuating circadian rhythm transcript profiles.. Am J Physiol Regul Integr Comp Physiol. 302(5):R587-97.
Moreau R, Nguyen BT, Doneanu CE, Hagen TM.  2005.  Reversal by aminoguanidine of the age-related increase in glycoxidation and lipoxidation in the cardiovascular system of Fischer 344 rats.. Biochem Pharmacol. 69(1):29-40.
Bobe G, Michels AJ, Zhang W-J, Purnell JQ, Woffendin C, Pereira C, Vita JA, Thomas NO, Traber MG, Frei B et al..  2020.  A Randomized Controlled Trial of Long-Term (R)-α-Lipoic Acid Supplementation Promotes Weight Loss in Overweight or Obese Adults without Altering Baseline Elevated Plasma Triglyceride Concentrations.. J Nutr. 150(9):2336-2345.
Smith AR, Visioli F, Hagen TM.  2006.  Plasma membrane-associated endothelial nitric oxide synthase and activity in aging rat aortic vascular endothelia markedly decline with age.. Arch Biochem Biophys. 454(1):100-5.
Rodríguez E, Dégletagne C, Hagen TM, Abele D, Blier PU.  2019.  Mitochondrial Traits Previously Associated With Species Maximum Lifespan Do Not Correlate With Longevity Across Populations of the Bivalve .. Front Physiol. 10:946.
Hagen TM, Moreau R, Suh JH, Visioli F.  2002.  Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid.. Ann N Y Acad Sci. 959:491-507.
Butler JA, Hagen TM, Moreau R.  2009.  Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and downregulating liver triacylglycerol secretion.. Arch Biochem Biophys. 485(1):63-71.
Michels AJ, Hagen TM, Frei B.  2013.  Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme function.. Annu Rev Nutr. 33:45-70.
Thomas NO, Shay KP, Kelley AR, Butler JA, Hagen TM.  2016.  Glutathione maintenance mitigates age-related susceptibility to redox cycling agents.. Redox Biol. 10:45-52.
Hagen TM, Liu J, Lykkesfeldt J, Wehr CM, Ingersoll RT, Vinarsky V, Bartholomew JC, Ames BN.  2002.  Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress.. Proc Natl Acad Sci U S A. 99(4):1870-5.
Rodríguez E, Hakkou M, Hagen TM, Lemieux H, Blier PU.  2020.  Divergences in the control of mitochondrial respiration are associated with lifespan variation in marine bivalves.. J Gerontol A Biol Sci Med Sci.
Suh JH, Moreau R, Heath S-HD, Hagen TM.  2005.  Dietary supplementation with (R)-alpha-lipoic acid reverses the age-related accumulation of iron and depletion of antioxidants in the rat cerebral cortex.. Redox Rep. 10(1):52-60.
Zhang W-J, Bird KE, McMillen TS, Leboeuf RC, Hagen TM, Frei B.  2008.  Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice.. Circulation. 117(3):421-8.
Suh JH, Shenvi SV, Dixon BM, Liu H, Jaiswal AK, Liu R-M, Hagen TM.  2004.  Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid.. Proc Natl Acad Sci U S A. 101(10):3381-6.
Monette JS, Gómez LA, Moreau RF, Bemer BA, Taylor AW, Hagen TM.  2010.  Characteristics of the rat cardiac sphingolipid pool in two mitochondrial subpopulations.. Biochem Biophys Res Commun. 398(2):272-7.
Shay KPetersen, Michels AJ, Li W, Kong A-NTony, Hagen TM.  2012.  Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response.. Biochim Biophys Acta. 1823(6):1102-9.
Dixon BM, Heath S-HD, Kim R, Suh JH, Hagen TM.  2008.  Assessment of endoplasmic reticulum glutathione redox status is confounded by extensive ex vivo oxidation.. Antioxid Redox Signal. 10(5):963-72.
Shay KPetersen, Moreau RF, Smith EJ, Smith AR, Hagen TM.  2009.  Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential.. Biochim Biophys Acta. 1790(10):1149-60.
Shay KPetersen, Moreau RF, Smith EJ, Hagen TM.  2008.  Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity. IUBMB Life. 60(6):362-7.