Found 118 results
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Young Adult
Hummel JM, Madeen EP, Siddens LK, Uesugi SL, McQuistan T, Anderson KA, Turteltaub KW, Ognibene TJ, Bench G, Krueger SK et al..  2018.  Pharmacokinetics of [C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction.. Food Chem Toxicol. 115:136-147.
Xenobiotics
Traber MG, Siddens LK, Leonard SW, Schock B, Gohil K, Krueger SK, Cross CE, Williams DE.  2005.  Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets.. Free Radic Biol Med. 38(6):773-85.
Vitamin E
Traber MG, Siddens LK, Leonard SW, Schock B, Gohil K, Krueger SK, Cross CE, Williams DE.  2005.  Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets.. Free Radic Biol Med. 38(6):773-85.
Time Factors
Siddens LK, Bunde KL, Harper TA, McQuistan TJ, Löhr CV, Bramer LM, Waters KM, Tilton SC, Krueger SK, Williams DE et al..  2015.  Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse.. Toxicol Appl Pharmacol. 287(2):149-160.
Traber MG, Siddens LK, Leonard SW, Schock B, Gohil K, Krueger SK, Cross CE, Williams DE.  2005.  Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets.. Free Radic Biol Med. 38(6):773-85.
Thiourea
Henderson MC, Siddens LK, Krueger SK, J Stevens F, Kedzie K, Fang WK, Heidelbaugh T, Nguyen P, Chow K, Garst M et al..  2014.  Flavin-containing monooxygenase S-oxygenation of a series of thioureas and thiones.. Toxicol Appl Pharmacol. 278(2):91-9.
Thiones
Henderson MC, Siddens LK, Krueger SK, J Stevens F, Kedzie K, Fang WK, Heidelbaugh T, Nguyen P, Chow K, Garst M et al..  2014.  Flavin-containing monooxygenase S-oxygenation of a series of thioureas and thiones.. Toxicol Appl Pharmacol. 278(2):91-9.
Tandem Mass Spectrometry
Siddens LK, Bunde KL, Harper TA, McQuistan TJ, Löhr CV, Bramer LM, Waters KM, Tilton SC, Krueger SK, Williams DE et al..  2015.  Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse.. Toxicol Appl Pharmacol. 287(2):149-160.
Sulfoxides
Krueger SK, Henderson MC, Siddens LK, VanDyke JE, Benninghoff AD, P Karplus A, Furnes B, Schlenk D, Williams DE.  2009.  Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K.. Drug Metab Dispos. 37(8):1785-91.
Structure-Activity Relationship
Krueger SK, Henderson MC, Siddens LK, VanDyke JE, Benninghoff AD, P Karplus A, Furnes B, Schlenk D, Williams DE.  2009.  Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K.. Drug Metab Dispos. 37(8):1785-91.
Skin Neoplasms
Siddens LK, Bunde KL, Harper TA, McQuistan TJ, Löhr CV, Bramer LM, Waters KM, Tilton SC, Krueger SK, Williams DE et al..  2015.  Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse.. Toxicol Appl Pharmacol. 287(2):149-160.
Sf9 Cells
Siddens LK, Krueger SK, Henderson MC, Williams DE.  2014.  Mammalian flavin-containing monooxygenase (FMO) as a source of hydrogen peroxide.. Biochem Pharmacol. 89(1):141-7.
Salmon
Hummel JM, Madeen EP, Siddens LK, Uesugi SL, McQuistan T, Anderson KA, Turteltaub KW, Ognibene TJ, Bench G, Krueger SK et al..  2018.  Pharmacokinetics of [C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction.. Food Chem Toxicol. 115:136-147.
RNA, Messenger
Siddens LK, Bunde KL, Harper TA, McQuistan TJ, Löhr CV, Bramer LM, Waters KM, Tilton SC, Krueger SK, Williams DE et al..  2015.  Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse.. Toxicol Appl Pharmacol. 287(2):149-160.
Siddens LK, Henderson MC, VanDyke JE, Williams DE, Krueger SK.  2008.  Characterization of mouse flavin-containing monooxygenase transcript levels in lung and liver, and activity of expressed isoforms.. Biochem Pharmacol. 75(2):570-9.
Recombinant Proteins
Krueger SK, Henderson MC, Siddens LK, VanDyke JE, Benninghoff AD, P Karplus A, Furnes B, Schlenk D, Williams DE.  2009.  Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K.. Drug Metab Dispos. 37(8):1785-91.
Protein Denaturation
Krueger SK, Henderson MC, Siddens LK, VanDyke JE, Benninghoff AD, P Karplus A, Furnes B, Schlenk D, Williams DE.  2009.  Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K.. Drug Metab Dispos. 37(8):1785-91.
Protein Conformation
Krueger SK, Henderson MC, Siddens LK, VanDyke JE, Benninghoff AD, P Karplus A, Furnes B, Schlenk D, Williams DE.  2009.  Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K.. Drug Metab Dispos. 37(8):1785-91.
Propionates
Traber MG, Siddens LK, Leonard SW, Schock B, Gohil K, Krueger SK, Cross CE, Williams DE.  2005.  Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets.. Free Radic Biol Med. 38(6):773-85.
Pregnancy Complications, Neoplastic
Madeen EP, Löhr CV, You H, Siddens LK, Krueger SK, Dashwood RH, Gonzalez FJ, Baird WM, Ho E, Bramer L et al..  2017.  Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.. Mol Carcinog. 56(1):163-171.
Pregnancy
Madeen EP, Löhr CV, You H, Siddens LK, Krueger SK, Dashwood RH, Gonzalez FJ, Baird WM, Ho E, Bramer L et al..  2017.  Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.. Mol Carcinog. 56(1):163-171.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Madeen EP, Löhr CV, You H, Siddens LK, Krueger SK, Dashwood RH, Gonzalez FJ, Baird WM, Ho E, Bramer L et al..  2017.  Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.. Mol Carcinog. 56(1):163-171.
Polymorphism, Single Nucleotide
Krueger SK, Henderson MC, Siddens LK, VanDyke JE, Benninghoff AD, P Karplus A, Furnes B, Schlenk D, Williams DE.  2009.  Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K.. Drug Metab Dispos. 37(8):1785-91.
Polycyclic Aromatic Hydrocarbons
Siddens LK, Bunde KL, Harper TA, McQuistan TJ, Löhr CV, Bramer LM, Waters KM, Tilton SC, Krueger SK, Williams DE et al..  2015.  Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse.. Toxicol Appl Pharmacol. 287(2):149-160.
Hummel JM, Madeen EP, Siddens LK, Uesugi SL, McQuistan T, Anderson KA, Turteltaub KW, Ognibene TJ, Bench G, Krueger SK et al..  2018.  Pharmacokinetics of [C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction.. Food Chem Toxicol. 115:136-147.

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