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Faculty and Staff
Our Research
Micronutrient Information
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Biblio
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Beaver, Laura M
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Journal Article
Beaver LM
,
Yu T-W
,
Sokolowski EI
,
Williams DE
,
Dashwood RH
,
Ho E
. 2012.
3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.
.
Toxicol Appl Pharmacol. 263(3):345-51.
Beaver LM
,
Nkrumah-Elie YM
,
Truong L
,
Barton CL
,
Knecht AL
,
Gonnerman GD
,
Wong CP
,
Tanguay RL
,
Ho E
. 2017.
Adverse effects of parental zinc deficiency on metal homeostasis and embryonic development in a zebrafish model.
.
J Nutr Biochem. 43:78-87.
Beaver LM
,
Lӧhr CV
,
Clarke JD
,
Glasser ST
,
Watson GW
,
Wong CP
,
Zhang Z
,
Williams DE
,
Dashwood RH
,
Shannon J
et al.
. 2018.
Broccoli Sprouts Delay Prostate Cancer Formation and Decrease Prostate Cancer Severity with a Concurrent Decrease in HDAC3 Protein Expression in Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) Mice.
.
Curr Dev Nutr. 2(3):nzy002.
Bouranis JA
,
Beaver LM
,
Choi J
,
Wong CP
,
Jiang D
,
Sharpton TJ
,
Stevens JF
,
Ho E
. 2021.
Composition of the Gut Microbiome Influences Production of Sulforaphane-Nitrile and Iberin-Nitrile from Glucosinolates in Broccoli Sprouts.
.
Nutrients. 13(9)
Beaver LM
,
Prati M
,
Gilman KE
,
Luo T
,
Shay NF
,
Branscum AJ
,
Turner RT
,
Iwaniec UT
. 2023.
Diet composition influences the effect of high fat diets on bone in growing male mice.
.
Bone. 176:116888.
Ho E
,
Beaver LM
,
Williams DE
,
Dashwood RH
. 2011.
Dietary factors and epigenetic regulation for prostate cancer prevention.
.
Adv Nutr. 2(6):497-510.
Wong CP
,
Hsu A
,
Buchanan A
,
Palomera-Sanchez Z
,
Beaver LM
,
E Houseman A
,
Williams DE
,
Dashwood RH
,
Ho E
. 2014.
Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells.
.
PLoS One. 9(1):e86787.
Atwell LL
,
Beaver LM
,
Shannon J
,
Williams DE
,
Dashwood RH
,
Ho E
. 2015.
Epigenetic Regulation by Sulforaphane: Opportunities for Breast and Prostate Cancer Chemoprevention.
.
Curr Pharmacol Rep. 1(2):102-111.
Johnson GS
,
Li J
,
Beaver LM
,
W Dashwood M
,
Sun D
,
Rajendran P
,
Williams DE
,
Ho E
,
Dashwood RH
. 2017.
A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a coactivator of NQO1 in sulforaphane-treated colon cancer cells.
.
Mol Nutr Food Res. 61(4)
Bouranis JA
,
Beaver LM
,
Jiang D
,
Choi J
,
Wong CP
,
Davis EW
,
Williams DE
,
Sharpton TJ
,
Stevens JF
,
Ho E
. 2022.
Interplay between Cruciferous Vegetables and the Gut Microbiome: A Multi-Omic Approach.
.
Nutrients. 15(1)
Beaver LM
,
Kuintzle R
,
Buchanan A
,
Wiley MW
,
Glasser ST
,
Wong CP
,
Johnson GS
,
Chang JH
,
Löhr CV
,
Williams DE
et al.
. 2017.
Long noncoding RNAs and sulforaphane: a target for chemoprevention and suppression of prostate cancer.
.
J Nutr Biochem. 42:72-83.
Bouranis JA
,
Beaver LM
,
Ho E
. 2021.
Metabolic Fate of Dietary Glucosinolates and Their Metabolites: A Role for the Microbiome.
.
Front Nutr. 8:748433.
Keller RM
,
Beaver LM
,
Prater MC
,
Truong L
,
Tanguay RL
,
Stevens JF
,
Hord NG
. 2022.
Nitrate exposure reprograms hepatic amino acid and nutrient sensing pathways prior to exercise: A metabolomic and transcriptomic investigation in zebrafish .
.
Front Mol Biosci. 9:903130.
Keller RMoon
,
Beaver LM
,
Reardon PN
,
Prater MC
,
Truong L
,
Robinson MM
,
Tanguay RL
,
Stevens JFred
,
Hord NG
. 2021.
Nitrate-induced improvements in exercise performance are coincident with exuberant changes in metabolic genes and the metabolome in zebrafish skeletal muscle.
.
J Appl Physiol (1985).
Palomera-Sanchez Z
,
Watson GW
,
Wong CP
,
Beaver LM
,
Williams DE
,
Dashwood RH
,
Ho E
. 2017.
The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.
.
J Nutr Biochem. 47:113-119.
Wang R
,
Yu Z
,
Sunchu B
,
Shoaf J
,
Dang I
,
Zhao S
,
Caples K
,
Bradley L
,
Beaver LM
,
Ho E
et al.
. 2017.
Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2-independent mechanism.
.
Aging Cell. 16(3):564-574.
Beaver LM
,
Song Y
,
Philbrick KA
,
Wong CP
,
Olson DA
,
Branscum AJ
,
Turner RT
,
Ho E
,
Iwaniec UT
. 2023.
Severe Zinc Deficiency Impairs Accrual of Bone in Rapidly Growing Rats That Is Partially Corrected Following Short-term Zinc Repletion.
.
Biol Trace Elem Res. 201(8):3834-3849.
Bouranis JA
,
Beaver LM
,
Wong CP
,
Choi J
,
Hamer S
,
Davis EW
,
Brown KS
,
Jiang D
,
Sharpton TJ
,
Stevens JF
et al.
. 2024.
Sulforaphane and Sulforaphane-Nitrile Metabolism in Humans Following Broccoli Sprout Consumption: Inter-individual Variation, Association with Gut Microbiome Composition, and Differential Bioactivity.
.
Mol Nutr Food Res. 68(4):e2300286.
Zhang Z
,
Garzotto M
,
Davis EW
,
Mori M
,
Stoller WA
,
Farris PE
,
Wong CP
,
Beaver LM
,
Thomas GV
,
Williams DE
et al.
. 2019.
Sulforaphane Bioavailability and Chemopreventive Activity in Men Presenting for Biopsy of the Prostate Gland: A Randomized Controlled Trial.
.
Nutr Cancer. :1-14.
Bouranis JA
,
Wong CP
,
Beaver LM
,
Uesugi SL
,
Papenhausen EM
,
Choi J
,
Davis EW
,
Da Silva ANunes
,
Kalengamaliro N
,
Chaudhary R
et al.
. 2023.
Sulforaphane Bioavailability in Healthy Subjects Fed a Single Serving of Fresh Broccoli Microgreens.
.
Foods. 12(20)
Axton ER
,
Beaver LM
,
St Mary L
,
Truong L
,
Logan CR
,
Spagnoli S
,
Prater MC
,
Keller RM
,
Garcia-Jaramillo M
,
Ehrlicher SE
et al.
. 2019.
Treatment with Nitrate, but Not Nitrite, Lowers the Oxygen Cost of Exercise and Decreases Glycolytic Intermediates While Increasing Fatty Acid Metabolites in Exercised Zebrafish.
.
J Nutr. 149(12):2120-2132.
Axton ER
,
Beaver LM
,
St Mary L
,
Truong L
,
Logan CR
,
Spagnoli S
,
Prater MC
,
Keller RM
,
Garcia-Jaramillo M
,
Ehrlicher SE
et al.
. 2019.
Treatment with Nitrate, but Not Nitrite, Lowers the Oxygen Cost of Exercise and Decreases Glycolytic Intermediates While Increasing Fatty Acid Metabolites in Exercised Zebrafish.
.
J Nutr. 149(12):2120-2132.
Housley L
,
Magana AAlcazar
,
Hsu A
,
Beaver LM
,
Wong CP
,
Stevens JF
,
Choi J
,
Jiang Y
,
Bella D
,
Williams DE
et al.
. 2018.
Untargeted Metabolomic Screen Reveals Changes in Human Plasma Metabolite Profiles Following Consumption of Fresh Broccoli Sprouts.
.
Mol Nutr Food Res.
Cao AL
,
Beaver LM
,
Wong CP
,
Hudson LG
,
Ho E
. 2019.
Zinc deficiency alters the susceptibility of pancreatic beta cells (INS-1) to arsenic exposure.
.
Biometals. 32(6):845-859.
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