Linus Pauling Institute

Legette LCL, Luna AYMoreno, Reed RL, Miranda CL, Bobe G, Proteau RR, Stevens JF.  2013.  Xanthohumol lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats.. Phytochemistry. 91:236-41.

Miranda CL, Elias VD, Hay JJ, Choi J, Reed RL, Stevens JF.  2016.  Xanthohumol improves dysfunctional glucose and lipid metabolism in diet-induced obese C57BL/6J mice.. Arch Biochem Biophys. 599:22-30.

Stevens JF, Page JE.  2004.  Xanthohumol and related prenylflavonoids from hops and beer: to your good health!. Phytochemistry. 65(10):1317-30.

Wright KM, Magana AAlcazar, Laethem RM, Moseley CL, Banks TT, Maier CS, Stevens JF, Quinn JF, Soumyanath A.  2020.  Water Extract Shows Low Potential for Cytochrome P450-Mediated Drug Interactions.. Drug Metab Dispos. 48(10):1053-1063.

Traber MG, Stevens JF.  2011.  Vitamins C and E: beneficial effects from a mechanistic perspective.. Free Radic Biol Med. 51(5):1000-13.

Kuiper HC, Bruno RS, Traber MG, Stevens JF.  2011.  Vitamin C supplementation lowers urinary levels of 4-hydroperoxy-2-nonenal metabolites in humans.. Free Radic Biol Med. 50(7):848-53.

Kirkwood JS, Lebold KM, Miranda CL, Wright CL, Miller GW, Tanguay RL, Barton CL, Traber MG, Stevens JF.  2012.  Vitamin C deficiency activates the purine nucleotide cycle in zebrafish.. J Biol Chem. 287(6):3833-41.

Sowell J, Frei B, Stevens JF.  2004.  Vitamin C conjugates of genotoxic lipid peroxidation products: structural characterization and detection in human plasma.. Proc Natl Acad Sci U S A. 101(52):17964-9.

Magana AAlcazar, Reed RL, Koluda R, Miranda CL, Maier CS, Stevens JF.  2020.  Vitamin C Activates the Folate-Mediated One-Carbon Cycle in C2C12 Myoblasts.. Antioxidants (Basel). 9(3)

Magana AAlcazar, Reed RL, Koluda R, Miranda CL, Maier CS, Stevens JF.  2020.  Vitamin C Activates the Folate-Mediated One-Carbon Cycle in C2C12 Myoblasts.. Antioxidants (Basel). 9(3)

Magana AAlcazar, Reed RL, Koluda R, Miranda CL, Maier CS, Stevens JF.  2020.  Vitamin C Activates the Folate-Mediated One-Carbon Cycle in C2C12 Myoblasts.. Antioxidants (Basel). 9(3)

Housley L, Magana AAlcazar, Hsu A, Beaver LM, Wong CP, Stevens JF, Choi J, Jiang Y, Bella D, Williams DE et al..  2018.  Untargeted Metabolomic Screen Reveals Changes in Human Plasma Metabolite Profiles Following Consumption of Fresh Broccoli Sprouts.. Mol Nutr Food Res.

Axton ER, Beaver LM, St Mary L, Truong L, Logan CR, Spagnoli S, Prater MC, Keller RM, Garcia-Jaramillo M, Ehrlicher SE et al..  2019.  Treatment with Nitrate, but Not Nitrite, Lowers the Oxygen Cost of Exercise and Decreases Glycolytic Intermediates While Increasing Fatty Acid Metabolites in Exercised Zebrafish.. J Nutr. 149(12):2120-2132.

Axton ER, Beaver LM, St Mary L, Truong L, Logan CR, Spagnoli S, Prater MC, Keller RM, Garcia-Jaramillo M, Ehrlicher SE et al..  2019.  Treatment with Nitrate, but Not Nitrite, Lowers the Oxygen Cost of Exercise and Decreases Glycolytic Intermediates While Increasing Fatty Acid Metabolites in Exercised Zebrafish.. J Nutr. 149(12):2120-2132.

Ellinwood DC, El-Mansy MF, Plagmann LS, Stevens JF, Maier CS, Gombart AF, Blakemore PR.  2017.  Total synthesis of [ C] -, [ C] -, and [ C] -isotopomers of xanthohumol, the principal prenylflavonoid from hops.. J Labelled Comp Radiopharm. 60(14):639-648.

Choi J, Shoaib M, Yin T, Nayyar G, Shinozaki K, Stevens JF, Becker LB, Kim J.  2019.  Tissue-Specific Metabolic Profiles After Prolonged Cardiac Arrest Reveal Brain Metabolome Dysfunction Predominantly After Resuscitation.. J Am Heart Assoc. 8(17):e012809.

Zhang Y, Bobe G, Miranda CL, Lowry MB, Hsu VL, Löhr CV, Wong CP, Jump DB, Robinson MM, Sharpton TJ et al..  2021.  Tetrahydroxanthohumol, a xanthohumol derivative, attenuates high-fat diet-induced hepatic steatosis by antagonizing PPARγ.. Elife. 10

Paraiso IL, Revel JS, Choi J, Miranda CL, Lak P, Kioussi C, Bobe G, Gombart AF, Raber J, Maier CS et al..  2020.  Targeting the Liver-Brain Axis with Hop-Derived Flavonoids Improves Lipid Metabolism and Cognitive Performance in Mice.. Mol Nutr Food Res. 64(15):e2000341.

Axton ER, Hardardt EA, Stevens JF.  2016.  Stable isotope-assisted LC-MS/MS monitoring of glyceryl trinitrate bioactivation in a cell culture model of nitrate tolerance.. J Chromatogr B Analyt Technol Biomed Life Sci. 1019:156-63.

Kirkwood JS, Maier C, Stevens JF.  2013.  Simultaneous, untargeted metabolic profiling of polar and nonpolar metabolites by LC-Q-TOF mass spectrometry.. Curr Protoc Toxicol. Chapter 4:Unit4.39.

Minato Y, Fassio SR, Kirkwood JS, Halang P, Quinn MJ, Faulkner WJ, Aagesen AM, Steuber J, Stevens JF, Häse CC.  2014.  Roles of the sodium-translocating NADH:quinone oxidoreductase (Na+-NQR) on vibrio cholerae metabolism, motility and osmotic stress resistance.. PLoS One. 9(5):e97083.

O'Connor A, Konda V, Reed RL, J Christensen M, Stevens JF, Contractor N.  2018.  Rice Protein Matrix Enhances Circulating Levels of Xanthohumol Following Acute Oral Intake of Spent Hops in Humans.. Mol Nutr Food Res. 62(6):e1700692.

Paraiso IL, Plagmann LS, Yang L, Zielke R, Gombart AF, Maier CS, Sikora AE, Blakemore PR, Stevens JF.  2019.  Reductive Metabolism of Xanthohumol and 8-Prenylnaringenin by the Intestinal Bacterium Eubacterium ramulus.. Mol Nutr Food Res. 63(2):e1800923.

Kuiper HC, Langsdorf BL, Miranda CL, Joss J, Jubert C, Mata JE, Stevens JF.  2010.  Quantitation of mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites in a smoking cessation study.. Free Radic Biol Med. 48(1):65-72.

Paraiso IL, Revel JS, Stevens JF.  2020.  Potential use of polyphenols in the battle against COVID-19.. Curr Opin Food Sci.