Linus Pauling Institute

Logan IE, Shulzhenko N, Sharpton TJ, Bobe G, Liu K, Nuss S, Jones ML, Miranda CL, Vasquez-Perez S, Pennington JM et al..  2021.  Xanthohumol Requires the Intestinal Microbiota to Improve Glucose Metabolism in Diet-Induced Obese Mice.. Mol Nutr Food Res. 65(21):e2100389.

Paraiso IL, Mattio LM, Magana AAlcazar, Choi J, Plagmann LS, Redick MA, Miranda CL, Maier CS, Dallavalle S, Kioussi C et al..  2021.  Xanthohumol Pyrazole Derivative Improves Diet-Induced Obesity and Induces Energy Expenditure in High-Fat Diet-Fed Mice.. ACS Pharmacol Transl Sci. 4(6):1782-1793.

Langley BO, Ryan JJoan, Phipps J, Buttolph L, Bray B, Aslan JE, Metz TO, Stevens JF, Bradley R.  2022.  Xanthohumol microbiome and signature in adults with Crohn's disease (the XMaS trial): a protocol for a phase II triple-masked, placebo-controlled clinical trial.. Trials. 23(1):885.

Legette LCL, Luna AYMoreno, Reed RL, Miranda CL, Bobe G, Proteau RR, Stevens JF.  2013.  Xanthohumol lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats.. Phytochemistry. 91:236-41.

Miranda CL, Elias VD, Hay JJ, Choi J, Reed RL, Stevens JF.  2016.  Xanthohumol improves dysfunctional glucose and lipid metabolism in diet-induced obese C57BL/6J mice.. Arch Biochem Biophys. 599:22-30.

Kundu P, Paraiso IL, Choi J, Miranda CL, Kioussi C, Maier CS, Bobe G, Stevens JF, Raber J.  2022.  Xanthohumol improves cognition in farnesoid X receptor-deficient mice on a high-fat diet.. Dis Model Mech. 15(11)

Stevens JF, Page JE.  2004.  Xanthohumol and related prenylflavonoids from hops and beer: to your good health!. Phytochemistry. 65(10):1317-30.

Cabey K, Long DM, Law A, Gray NE, McClure C, Caruso M, Lak P, Wright KM, Stevens JF, Maier CS et al..  2022.   Withania somnifera and Centella asiatica Extracts Ameliorate Behavioral Deficits in an In Vivo Drosophila melanogaster Model of Oxidative Stress.. Antioxidants (Basel). 11(1)

Wright KM, Magana AAlcazar, Laethem RM, Moseley CL, Banks TT, Maier CS, Stevens JF, Quinn JF, Soumyanath A.  2020.  Water Extract Shows Low Potential for Cytochrome P450-Mediated Drug Interactions.. Drug Metab Dispos. 48(10):1053-1063.

Traber MG, Stevens JF.  2011.  Vitamins C and E: beneficial effects from a mechanistic perspective.. Free Radic Biol Med. 51(5):1000-13.

Kuiper HC, Bruno RS, Traber MG, Stevens JF.  2011.  Vitamin C supplementation lowers urinary levels of 4-hydroperoxy-2-nonenal metabolites in humans.. Free Radic Biol Med. 50(7):848-53.

Kirkwood JS, Lebold KM, Miranda CL, Wright CL, Miller GW, Tanguay RL, Barton CL, Traber MG, Stevens JF.  2012.  Vitamin C deficiency activates the purine nucleotide cycle in zebrafish.. J Biol Chem. 287(6):3833-41.

Sowell J, Frei B, Stevens JF.  2004.  Vitamin C conjugates of genotoxic lipid peroxidation products: structural characterization and detection in human plasma.. Proc Natl Acad Sci U S A. 101(52):17964-9.

Magana AAlcazar, Reed RL, Koluda R, Miranda CL, Maier CS, Stevens JF.  2020.  Vitamin C Activates the Folate-Mediated One-Carbon Cycle in C2C12 Myoblasts.. Antioxidants (Basel). 9(3)

Magana AAlcazar, Reed RL, Koluda R, Miranda CL, Maier CS, Stevens JF.  2020.  Vitamin C Activates the Folate-Mediated One-Carbon Cycle in C2C12 Myoblasts.. Antioxidants (Basel). 9(3)

Magana AAlcazar, Reed RL, Koluda R, Miranda CL, Maier CS, Stevens JF.  2020.  Vitamin C Activates the Folate-Mediated One-Carbon Cycle in C2C12 Myoblasts.. Antioxidants (Basel). 9(3)

Housley L, Magana AAlcazar, Hsu A, Beaver LM, Wong CP, Stevens JF, Choi J, Jiang Y, Bella D, Williams DE et al..  2018.  Untargeted Metabolomic Screen Reveals Changes in Human Plasma Metabolite Profiles Following Consumption of Fresh Broccoli Sprouts.. Mol Nutr Food Res.

Axton ER, Beaver LM, St Mary L, Truong L, Logan CR, Spagnoli S, Prater MC, Keller RM, Garcia-Jaramillo M, Ehrlicher SE et al..  2019.  Treatment with Nitrate, but Not Nitrite, Lowers the Oxygen Cost of Exercise and Decreases Glycolytic Intermediates While Increasing Fatty Acid Metabolites in Exercised Zebrafish.. J Nutr. 149(12):2120-2132.

Axton ER, Beaver LM, St Mary L, Truong L, Logan CR, Spagnoli S, Prater MC, Keller RM, Garcia-Jaramillo M, Ehrlicher SE et al..  2019.  Treatment with Nitrate, but Not Nitrite, Lowers the Oxygen Cost of Exercise and Decreases Glycolytic Intermediates While Increasing Fatty Acid Metabolites in Exercised Zebrafish.. J Nutr. 149(12):2120-2132.

Ellinwood DC, El-Mansy MF, Plagmann LS, Stevens JF, Maier CS, Gombart AF, Blakemore PR.  2017.  Total synthesis of [ C] -, [ C] -, and [ C] -isotopomers of xanthohumol, the principal prenylflavonoid from hops.. J Labelled Comp Radiopharm. 60(14):639-648.

Choi J, Shoaib M, Yin T, Nayyar G, Shinozaki K, Stevens JF, Becker LB, Kim J.  2019.  Tissue-Specific Metabolic Profiles After Prolonged Cardiac Arrest Reveal Brain Metabolome Dysfunction Predominantly After Resuscitation.. J Am Heart Assoc. 8(17):e012809.

Zhang Y, Bobe G, Miranda CL, Lowry MB, Hsu VL, Löhr CV, Wong CP, Jump DB, Robinson MM, Sharpton TJ et al..  2021.  Tetrahydroxanthohumol, a xanthohumol derivative, attenuates high-fat diet-induced hepatic steatosis by antagonizing PPARγ.. Elife. 10

Paraiso IL, Revel JS, Choi J, Miranda CL, Lak P, Kioussi C, Bobe G, Gombart AF, Raber J, Maier CS et al..  2020.  Targeting the Liver-Brain Axis with Hop-Derived Flavonoids Improves Lipid Metabolism and Cognitive Performance in Mice.. Mol Nutr Food Res. 64(15):e2000341.

Bouranis JA, Beaver LM, Wong CP, Choi J, Hamer S, Davis EW, Brown KS, Jiang D, Sharpton TJ, Stevens JF et al..  2024.  Sulforaphane and Sulforaphane-Nitrile Metabolism in Humans Following Broccoli Sprout Consumption: Inter-individual Variation, Association with Gut Microbiome Composition, and Differential Bioactivity.. Mol Nutr Food Res. 68(4):e2300286.

Axton ER, Hardardt EA, Stevens JF.  2016.  Stable isotope-assisted LC-MS/MS monitoring of glyceryl trinitrate bioactivation in a cell culture model of nitrate tolerance.. J Chromatogr B Analyt Technol Biomed Life Sci. 1019:156-63.