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About the LPI
Faculty and Staff
Our Research
Micronutrient Information
Publications
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Biblio
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Copper
Zhang WJian
,
Frei B
. 2003.
Intracellular metal ion chelators inhibit TNFalpha-induced SP-1 activation and adhesion molecule expression in human aortic endothelial cells.
.
Free Radic Biol Med. 34(6):674-82.
Cross-Sectional Studies
Blumberg JB
,
Frei B
,
Fulgoni VL
,
Weaver CM
,
Zeisel SH
. 2017.
Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups.
.
Nutrients. 9(12)
Crosses, Genetic
Smith AR
,
Visioli F
,
Frei B
,
Hagen TM
. 2006.
Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A.
.
Aging Cell. 5(5):391-400.
Culture Media, Conditioned
Lotito SB
,
Frei B
. 2006.
Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism.
.
J Biol Chem. 281(48):37102-10.
Cyclic N-Oxides
Zhu B-Z
,
Zhao H-T
,
Kalyanaraman B
,
Frei B
. 2002.
Metal-independent production of hydroxyl radicals by halogenated quinones and hydrogen peroxide: an ESR spin trapping study.
.
Free Radic Biol Med. 32(5):465-73.
Cyclohexanones
Zhu B-Z
,
Carr AC
,
Frei B
. 2002.
Pyrrolidine dithiocarbamate is a potent antioxidant against hypochlorous acid-induced protein damage.
.
FEBS Lett. 532(1-2):80-4.
Cytochrome b Group
Li L
,
Frei B
. 2006.
Iron chelation inhibits NF-kappaB-mediated adhesion molecule expression by inhibiting p22(phox) protein expression and NADPH oxidase activity.
.
Arterioscler Thromb Vasc Biol. 26(12):2638-43.
Cytokines
Zhang W-J
,
Wei H
,
Tien Y-T
,
Frei B
. 2011.
Genetic ablation of phagocytic NADPH oxidase in mice limits TNFα-induced inflammation in the lungs but not other tissues.
.
Free Radic Biol Med. 50(11):1517-25.
Wei H
,
Zhang W-J
,
McMillen TS
,
Leboeuf RC
,
Frei B
. 2012.
Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice.
.
Atherosclerosis. 223(2):306-13.
Zhang W-J
,
Wei H
,
Frei B
. 2009.
Genetic deficiency of NADPH oxidase does not diminish, but rather enhances, LPS-induced acute inflammatory responses in vivo.
.
Free Radic Biol Med. 46(6):791-8.
Deferoxamine
Zhang WJian
,
Frei B
. 2003.
Intracellular metal ion chelators inhibit TNFalpha-induced SP-1 activation and adhesion molecule expression in human aortic endothelial cells.
.
Free Radic Biol Med. 34(6):674-82.
Li L
,
Frei B
. 2006.
Iron chelation inhibits NF-kappaB-mediated adhesion molecule expression by inhibiting p22(phox) protein expression and NADPH oxidase activity.
.
Arterioscler Thromb Vasc Biol. 26(12):2638-43.
Zhang W-J
,
Wei H
,
Frei B
. 2010.
The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice.
.
Exp Biol Med (Maywood). 235(5):633-41.
Li L
,
Frei B
. 2009.
Prolonged exposure to LPS increases iron, heme, and p22phox levels and NADPH oxidase activity in human aortic endothelial cells: inhibition by desferrioxamine.
.
Arterioscler Thromb Vasc Biol. 29(5):732-8.
Deficiency Diseases
Blumberg JB
,
Frei B
,
Fulgoni VL
,
Weaver CM
,
Zeisel SH
. 2017.
Contribution of Dietary Supplements to Nutritional Adequacy by Socioeconomic Subgroups in Adults of the United States.
.
Nutrients. 10(1)
Depression
Kerr DCR
,
Zava DT
,
Piper WT
,
Saturn SR
,
Frei B
,
Gombart AF
. 2015.
Associations between vitamin D levels and depressive symptoms in healthy young adult women.
.
Psychiatry Res. 227(1):46-51.
Diabetes Mellitus, Type 2
Higdon JV
,
Frei B
. 2006.
Coffee and health: a review of recent human research.
.
Crit Rev Food Sci Nutr. 46(2):101-23.
Diet
Kerr DCR
,
Zava DT
,
Piper WT
,
Saturn SR
,
Frei B
,
Gombart AF
. 2015.
Associations between vitamin D levels and depressive symptoms in healthy young adult women.
.
Psychiatry Res. 227(1):46-51.
Lotito SB
,
Frei B
. 2006.
Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon?
Free Radic Biol Med. 41(12):1727-46.
Lotito SB
,
Frei B
. 2004.
Relevance of apple polyphenols as antioxidants in human plasma: contrasting in vitro and in vivo effects.
.
Free Radic Biol Med. 36(2):201-11.
Lotito SB
,
Zhang W-J
,
Yang CS
,
Crozier A
,
Frei B
. 2011.
Metabolic conversion of dietary flavonoids alters their anti-inflammatory and antioxidant properties.
.
Free Radic Biol Med. 51(2):454-63.
Mastaloudis A
,
Yu T-W
,
O'Donnell RP
,
Frei B
,
Dashwood RH
,
Traber MG
. 2004.
Endurance exercise results in DNA damage as detected by the comet assay.
.
Free Radic Biol Med. 36(8):966-75.
Blumberg JB
,
Frei B
,
Fulgoni VL
,
Weaver CM
,
Zeisel SH
. 2017.
Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups.
.
Nutrients. 9(12)
Dietary Supplements
Frei B
,
Birlouez-Aragon I
,
Lykkesfeldt J
. 2012.
Authors' perspective: What is the optimum intake of vitamin C in humans?
Crit Rev Food Sci Nutr. 52(9):815-29.
Blumberg JB
,
Frei B
,
Fulgoni VL
,
Weaver CM
,
Zeisel SH
. 2017.
Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups.
.
Nutrients. 9(12)
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