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Faculty and Staff
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Micronutrient Information
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Biblio
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Antioxidants
Lotito SB
,
Frei B
. 2006.
Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon?
Free Radic Biol Med. 41(12):1727-46.
Carr AC
,
Frei B
. 2002.
Human neutrophils oxidize low-density lipoprotein by a hypochlorous acid-dependent mechanism: the role of vitamin C.
.
Biol Chem. 383(3-4):627-36.
Lotito SB
,
Frei B
. 2004.
The increase in human plasma antioxidant capacity after apple consumption is due to the metabolic effect of fructose on urate, not apple-derived antioxidant flavonoids.
.
Free Radic Biol Med. 37(2):251-8.
Lotito SB
,
Frei B
. 2006.
Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism.
.
J Biol Chem. 281(48):37102-10.
Visioli F
,
Smith A
,
Zhang W
,
Keaney JF
,
Hagen T
,
Frei B
. 2002.
Lipoic acid and vitamin C potentiate nitric oxide synthesis in human aortic endothelial cells independently of cellular glutathione status.
.
Redox Rep. 7(4):223-7.
Zhang W-J
,
Wei H
,
Hagen T
,
Frei B
. 2007.
Alpha-lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway.
.
Proc Natl Acad Sci U S A. 104(10):4077-82.
Higdon JV
,
Frei B
. 2005.
Is there a gender difference in the effect of antioxidants on cancer risk?
Br J Nutr. 94(2):139-40.
Frei B
,
Lawson S
. 2008.
Vitamin C and cancer revisited.
.
Proc Natl Acad Sci U S A. 105(32):11037-8.
Mastaloudis A
,
Yu T-W
,
O'Donnell RP
,
Frei B
,
Dashwood RH
,
Traber MG
. 2004.
Endurance exercise results in DNA damage as detected by the comet assay.
.
Free Radic Biol Med. 36(8):966-75.
Lotito SB
,
Zhang W-J
,
Yang CS
,
Crozier A
,
Frei B
. 2011.
Metabolic conversion of dietary flavonoids alters their anti-inflammatory and antioxidant properties.
.
Free Radic Biol Med. 51(2):454-63.
Frei B
,
Birlouez-Aragon I
,
Lykkesfeldt J
. 2012.
Authors' perspective: What is the optimum intake of vitamin C in humans?
Crit Rev Food Sci Nutr. 52(9):815-29.
Lotito SB
,
Frei B
. 2004.
Relevance of apple polyphenols as antioxidants in human plasma: contrasting in vitro and in vivo effects.
.
Free Radic Biol Med. 36(2):201-11.
Li C
,
Zhang W-J
,
Frei B
. 2016.
Quercetin inhibits LPS-induced adhesion molecule expression and oxidant production in human aortic endothelial cells by p38-mediated Nrf2 activation and antioxidant enzyme induction.
.
Redox Biol. 9:104-113.
Traber MG
,
Frei B
,
Beckman JS
. 2008.
Vitamin E revisited: do new data validate benefits for chronic disease prevention?
Curr Opin Lipidol. 19(1):30-8.
Li C
,
Zhang W-J
,
Choi J
,
Frei B
. 2016.
Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase.
.
Redox Biol. 9:220-228.
Zhu B-Z
,
Carr AC
,
Frei B
. 2002.
Pyrrolidine dithiocarbamate is a potent antioxidant against hypochlorous acid-induced protein damage.
.
FEBS Lett. 532(1-2):80-4.
Antineoplastic Agents
Frei B
,
Lawson S
. 2008.
Vitamin C and cancer revisited.
.
Proc Natl Acad Sci U S A. 105(32):11037-8.
Anticarcinogenic Agents
Higdon JV
,
Frei B
. 2005.
Is there a gender difference in the effect of antioxidants on cancer risk?
Br J Nutr. 94(2):139-40.
Anti-Inflammatory Agents, Non-Steroidal
Mastaloudis A
,
Yu T-W
,
O'Donnell RP
,
Frei B
,
Dashwood RH
,
Traber MG
. 2004.
Endurance exercise results in DNA damage as detected by the comet assay.
.
Free Radic Biol Med. 36(8):966-75.
Anti-Inflammatory Agents
Lotito SB
,
Zhang W-J
,
Yang CS
,
Crozier A
,
Frei B
. 2011.
Metabolic conversion of dietary flavonoids alters their anti-inflammatory and antioxidant properties.
.
Free Radic Biol Med. 51(2):454-63.
Wei H
,
Frei B
,
Beckman JS
,
Zhang W-J
. 2011.
Copper chelation by tetrathiomolybdate inhibits lipopolysaccharide-induced inflammatory responses in vivo.
.
Am J Physiol Heart Circ Physiol. 301(3):H712-20.
Zhang W-J
,
Frei B
. 2002.
Albumin selectively inhibits TNF alpha-induced expression of vascular cell adhesion molecule-1 in human aortic endothelial cells.
.
Cardiovasc Res. 55(4):820-9.
Wei H
,
Zhang W-J
,
McMillen TS
,
Leboeuf RC
,
Frei B
. 2012.
Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice.
.
Atherosclerosis. 223(2):306-13.
Lotito SB
,
Frei B
. 2006.
Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism.
.
J Biol Chem. 281(48):37102-10.
Zhang W-J
,
Wei H
,
Hagen T
,
Frei B
. 2007.
Alpha-lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway.
.
Proc Natl Acad Sci U S A. 104(10):4077-82.
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