Linus Pauling Institute

Kuiper HC, Miranda CL, Sowell JD, Stevens JF.  2008.  Mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites are in vivo markers of oxidative stress.. J Biol Chem. 283(25):17131-8.

Miranda CL, Reed RL, Kuiper HC, Alber S, Stevens JF.  2009.  Ascorbic acid promotes detoxification and elimination of 4-hydroxy-2(E)-nonenal in human monocytic THP-1 cells.. Chem Res Toxicol. 22(5):863-74.

Kesinger NG, Langsdorf BL, Yokochi AF, Miranda CL, Stevens JF.  2010.  Formation of a vitamin C conjugate of acrolein and its paraoxonase-mediated conversion into 5,6,7,8-tetrahydroxy-4-oxooctanal.. Chem Res Toxicol. 23(4):836-44.

Kuiper HC, Langsdorf BL, Miranda CL, Joss J, Jubert C, Mata JE, Stevens JF.  2010.  Quantitation of mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites in a smoking cessation study.. Free Radic Biol Med. 48(1):65-72.

Peluso MR, Miranda CL, Hobbs DJ, Proteau RR, Stevens JFrederik.  2010.  Xanthohumol and related prenylated flavonoids inhibit inflammatory cytokine production in LPS-activated THP-1 monocytes: structure-activity relationships and in silico binding to myeloid differentiation protein-2 (MD-2).. Planta Med. 76(14):1536-43.

Legette LC, Ma L, Reed RL, Miranda CL, Christensen JMark, Rodriguez-Proteau R, Stevens JF.  2012.  Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.. Mol Nutr Food Res. 56(3):466-74.

Kirkwood JS, Lebold KM, Miranda CL, Wright CL, Miller GW, Tanguay RL, Barton CL, Traber MG, Stevens JF.  2012.  Vitamin C deficiency activates the purine nucleotide cycle in zebrafish.. J Biol Chem. 287(6):3833-41.

Kirkwood JS, Legette LCL, Miranda CL, Jiang Y, Stevens JF.  2013.  A metabolomics-driven elucidation of the anti-obesity mechanisms of xanthohumol.. J Biol Chem. 288(26):19000-13.

Legette LCL, Luna AYMoreno, Reed RL, Miranda CL, Bobe G, Proteau RR, Stevens JF.  2013.  Xanthohumol lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats.. Phytochemistry. 91:236-41.

Kirkwood JS, Miranda CL, Bobe G, Maier CS, Stevens JF.  2016.  18O-Tracer Metabolomics Reveals Protein Turnover and CDP-Choline Cycle Activity in Differentiating 3T3-L1 Pre-Adipocytes.. PLoS One. 11(6):e0157118.

Miranda CL, Elias VD, Hay JJ, Choi J, Reed RL, Stevens JF.  2016.  Xanthohumol improves dysfunctional glucose and lipid metabolism in diet-induced obese C57BL/6J mice.. Arch Biochem Biophys. 599:22-30.

Axton ERose, Cristobal E, Choi J, Miranda CL, Stevens JFrederik.  2018.  Metabolomics-Driven Elucidation of Cellular Nitrate Tolerance Reveals Ascorbic Acid Prevents Nitroglycerin-Induced Inactivation of Xanthine Oxidase.. Front Pharmacol. 9:1085.

Miranda CL, Johnson LA, de Montgolfier O, Elias VD, Ullrich LS, Hay JJ, Paraiso IL, Choi J, Reed RL, Revel JS et al..  2018.  Non-estrogenic Xanthohumol Derivatives Mitigate Insulin Resistance and Cognitive Impairment in High-Fat Diet-induced Obese Mice.. Sci Rep. 8(1):613.

Carpenter EL, Le MN, Miranda CL, Reed RL, Stevens JF, Indra AK, Ganguli-Indra G.  2018.  Photoprotective Properties of Isothiocyanate and Nitrile Glucosinolate Derivatives From Meadowfoam () Against UVB Irradiation in Human Skin Equivalent.. Front Pharmacol. 9:477.

Bading-Taika B, Akinyeke T, Magana AAlcazar, Choi J, Ouanesisouk M, Torres ERuth Samso, Lione LA, Maier CS, Bobe G, Raber J et al..  2018.  Phytochemical characterization of root bark and its effects on dysfunctional metabolism and cognitive performance in high-fat-fed C57BL/6J mice.. J Food Bioact. 3:111-123.

Logan IE, Miranda CL, Lowry MB, Maier CS, Stevens JF, Gombart AF.  2019.  Antiproliferative and Cytotoxic Activity of Xanthohumol and Its Non-Estrogenic Derivatives in Colon and Hepatocellular Carcinoma Cell Lines.. Int J Mol Sci. 20(5)

Song Z, Pearce MC, Jiang Y, Yang L, Goodall C, Miranda CL, Milovancev M, Bracha S, Kolluri SK, Maier CS.  2020.  Delineation of hypoxia-induced proteome shifts in osteosarcoma cells with different metastatic propensities.. Sci Rep. 10(1):727.

Song Z, Pearce MC, Jiang Y, Yang L, Goodall C, Miranda CL, Milovancev M, Bracha S, Kolluri SK, Maier CS.  2020.  Delineation of hypoxia-induced proteome shifts in osteosarcoma cells with different metastatic propensities.. Sci Rep. 10(1):727.

Logan IE, Bobe G, Miranda CL, Vasquez-Perez S, Choi J, Lowry MB, Sharpton TJ, Morgun A, Maier CS, Stevens JF et al..  2020.  Germ-Free Swiss Webster Mice on a High-Fat Diet Develop Obesity, Hyperglycemia, and Dyslipidemia.. Microorganisms. 8(4)

Logan IE, Bobe G, Miranda CL, Vasquez-Perez S, Choi J, Lowry MB, Sharpton TJ, Morgun A, Maier CS, Stevens JF et al..  2020.  Germ-Free Swiss Webster Mice on a High-Fat Diet Develop Obesity, Hyperglycemia, and Dyslipidemia.. Microorganisms. 8(4)

Zhang Y, Bobe G, Revel JS, Rodrigues RR, Sharpton TJ, Fantacone ML, Raslan K, Miranda CL, Lowry MB, Blakemore PR et al..  2020.  Improvements in Metabolic Syndrome by Xanthohumol Derivatives Are Linked to Altered Gut Microbiota and Bile Acid Metabolism.. Mol Nutr Food Res. 64(1):e1900789.

Zhang Y, Bobe G, Revel JS, Rodrigues RR, Sharpton TJ, Fantacone ML, Raslan K, Miranda CL, Lowry MB, Blakemore PR et al..  2020.  Improvements in Metabolic Syndrome by Xanthohumol Derivatives Are Linked to Altered Gut Microbiota and Bile Acid Metabolism.. Mol Nutr Food Res. 64(1):e1900789.

Paraiso IL, Revel JS, Choi J, Miranda CL, Lak P, Kioussi C, Bobe G, Gombart AF, Raber J, Maier CS et al..  2020.  Targeting the Liver-Brain Axis with Hop-Derived Flavonoids Improves Lipid Metabolism and Cognitive Performance in Mice.. Mol Nutr Food Res. 64(15):e2000341.

Magana AAlcazar, Reed RL, Koluda R, Miranda CL, Maier CS, Stevens JF.  2020.  Vitamin C Activates the Folate-Mediated One-Carbon Cycle in C2C12 Myoblasts.. Antioxidants (Basel). 9(3)

Magana AAlcazar, Reed RL, Koluda R, Miranda CL, Maier CS, Stevens JF.  2020.  Vitamin C Activates the Folate-Mediated One-Carbon Cycle in C2C12 Myoblasts.. Antioxidants (Basel). 9(3)