Found 909 results
Author [ Keyword(Desc)] Title Type Year
Filters: Author is Dashwood, Roderick H  [Clear All Filters]
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Amines
Dashwood RH.  2003.  Use of transgenic and mutant animal models in the study of heterocyclic amine-induced mutagenesis and carcinogenesis.. J Biochem Mol Biol. 36(1):35-42.
Chen Y-S, Wang R, Dashwood W-M, Löhr CV, Williams DE, Ho E, Mertens-Talcott S, Dashwood RH.  2017.  A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat.. Arch Toxicol. 91(10):3415-3425.
Amino Acid Sequence
Li Q, Dixon BM, Al-Fageeh M, Blum CA, Dashwood RH.  2002.  Sequencing of the rat beta-catenin gene (Ctnnb1) and mutational analysis of liver tumors induced by 2-amino-3-methylimidazo[4,5-f]quinoline.. Gene. 283(1-2):255-62.
Amino Acid Substitution
Al-Fageeh M, Li Q, W Dashwood M, Myzak MC, Dashwood RH.  2004.  Phosphorylation and ubiquitination of oncogenic mutants of beta-catenin containing substitutions at Asp32.. Oncogene. 23(28):4839-46.
Analysis of Variance
Wong CP, Hsu A, Buchanan A, Palomera-Sanchez Z, Beaver LM, E Houseman A, Williams DE, Dashwood RH, Ho E.  2014.  Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells.. PLoS One. 9(1):e86787.
Androgen Receptor Antagonists
Palomera-Sanchez Z, Watson GW, Wong CP, Beaver LM, Williams DE, Dashwood RH, Ho E.  2017.  The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.. J Nutr Biochem. 47:113-119.
Androgens
Beaver LM, Yu T-W, Sokolowski EI, Williams DE, Dashwood RH, Ho E.  2012.  3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.. Toxicol Appl Pharmacol. 263(3):345-51.
Myzak MC, Hardin K, Wang R, Dashwood RH, Ho E.  2006.  Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells.. Carcinogenesis. 27(4):811-9.
Animal Feed
McQuistan TJ, Simonich MT, M Pratt M, Pereira CB, Hendricks JD, Dashwood RH, Williams DE, Bailey GS.  2012.  Cancer chemoprevention by dietary chlorophylls: a 12,000-animal dose-dose matrix biomarker and tumor study.. Food Chem Toxicol. 50(2):341-52.
Animals
Li Q, Dixon BM, Al-Fageeh M, Blum CA, Dashwood RH.  2002.  Sequencing of the rat beta-catenin gene (Ctnnb1) and mutational analysis of liver tumors induced by 2-amino-3-methylimidazo[4,5-f]quinoline.. Gene. 283(1-2):255-62.
Larsen CA, Dashwood RH, Bisson WH.  2010.  Tea catechins as inhibitors of receptor tyrosine kinases: mechanistic insights and human relevance.. Pharmacol Res. 62(6):457-64.
Dashwood RH.  2003.  Use of transgenic and mutant animal models in the study of heterocyclic amine-induced mutagenesis and carcinogenesis.. J Biochem Mol Biol. 36(1):35-42.
Blum CA, Xu M, Orner GA, G Díaz D, Li Q, Dashwood WMohaiza, Bailey GS, Dashwood RH.  2003.  Promotion versus suppression of rat colon carcinogenesis by chlorophyllin and chlorophyll: modulation of apoptosis, cell proliferation, and beta-catenin/Tcf signaling.. Mutat Res. 523-524:217-23.
Orner GA, Dashwood W-M, Dashwood RH.  2004.  Tumor-suppressing effects of antioxidants from tea.. J Nutr. 134(11):3177S-3178S.
Wang R, Kang Y, Löhr CV, Fischer KA, C Bradford S, Johnson G, Dashwood WMohaiza, Williams DE, Ho E, Dashwood RH.  2016.  Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer.. Cancer Lett. 381(2):341-8.
Myzak MC, Dashwood RH.  2006.  Histone deacetylases as targets for dietary cancer preventive agents: lessons learned with butyrate, diallyl disulfide, and sulforaphane.. Curr Drug Targets. 7(4):443-52.
Li Q, Löhr CV, Dashwood RH.  2009.  Activator protein 2alpha suppresses intestinal tumorigenesis in the Apc(min) mouse.. Cancer Lett. 283(1):36-42.
Li Q, Dashwood W-M, Zhong X, Al-Fageeh M, Dashwood RH.  2004.  Cloning of the rat beta-catenin gene (Ctnnb1) promoter and its functional analysis compared with the Catnb and CTNNB1 promoters.. Genomics. 83(2):231-42.
Wang R, W Dashwood M, Bailey GS, Williams DE, Dashwood RH.  2006.  Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in beta-catenin that are independent of beta-catenin mutation status.. Mutat Res. 601(1-2):11-8.
Dashwood RH, Ho E.  2008.  Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates.. Nutr Rev. 66 Suppl 1:S36-8.
Orner GA, Dashwood W-M, Blum CA, G Díaz D, Li Q, Dashwood RH.  2003.  Suppression of tumorigenesis in the Apc(min) mouse: down-regulation of beta-catenin signaling by a combination of tea plus sulindac.. Carcinogenesis. 24(2):263-7.
Simonich MT, Egner PA, Roebuck BD, Orner GA, Jubert C, Pereira C, Groopman JD, Kensler TW, Dashwood RH, Williams DE et al..  2007.  Natural chlorophyll inhibits aflatoxin B1-induced multi-organ carcinogenesis in the rat.. Carcinogenesis. 28(6):1294-302.
Simonich MT, McQuistan T, Jubert C, Pereira C, Hendricks JD, Schimerlik M, Zhu B, Dashwood RH, Williams DE, Bailey GS.  2008.  Low-dose dietary chlorophyll inhibits multi-organ carcinogenesis in the rainbow trout.. Food Chem Toxicol. 46(3):1014-24.
Parasramka MA, Ho E, Williams DE, Dashwood RH.  2012.  MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals.. Mol Carcinog. 51(3):213-30.
Wang R, Dashwood W-M, Nian H, Löhr CV, Fischer KA, Tsuchiya N, Nakagama H, Ashktorab H, Dashwood RH.  2011.  NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).. Int J Cancer. 128(11):2581-90.

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