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Found 909 results
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Dashwood, Roderick H
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Colonic Neoplasms
Al-Fageeh M
,
Li Q
,
W Dashwood M
,
Myzak MC
,
Dashwood RH
. 2004.
Phosphorylation and ubiquitination of oncogenic mutants of beta-catenin containing substitutions at Asp32.
.
Oncogene. 23(28):4839-46.
Wang R
,
W Dashwood M
,
Löhr CV
,
Fischer KA
,
Pereira CB
,
Louderback M
,
Nakagama H
,
Bailey GS
,
Williams DE
,
Dashwood RH
. 2008.
Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat.
.
Carcinogenesis. 29(4):834-9.
Orner GA
,
Dashwood W-M
,
Dashwood RH
. 2004.
Tumor-suppressing effects of antioxidants from tea.
.
J Nutr. 134(11):3177S-3178S.
Larsen CA
,
Bisson WH
,
Dashwood RH
. 2009.
Tea catechins inhibit hepatocyte growth factor receptor (MET kinase) activity in human colon cancer cells: kinetic and molecular docking studies.
.
J Med Chem. 52(21):6543-5.
Johnson GS
,
Li J
,
Beaver LM
,
W Dashwood M
,
Sun D
,
Rajendran P
,
Williams DE
,
Ho E
,
Dashwood RH
. 2017.
A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a coactivator of NQO1 in sulforaphane-treated colon cancer cells.
.
Mol Nutr Food Res. 61(4)
Rajendran P
,
Kidane AI
,
Yu T-W
,
Dashwood W-M
,
Bisson WH
,
Löhr CV
,
Ho E
,
Williams DE
,
Dashwood RH
. 2013.
HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates.
.
Epigenetics. 8(6):612-23.
Colorectal Neoplasms
Li Q
,
Löhr CV
,
Dashwood RH
. 2009.
Activator protein 2alpha suppresses intestinal tumorigenesis in the Apc(min) mouse.
.
Cancer Lett. 283(1):36-42.
Dashwood W-M
,
Carter O
,
Al-Fageeh M
,
Li Q
,
Dashwood RH
. 2005.
Lysosomal trafficking of beta-catenin induced by the tea polyphenol epigallocatechin-3-gallate.
.
Mutat Res. 591(1-2):161-72.
Wang R
,
Chen Y-S
,
Dashwood W-M
,
Li Q
,
Löhr CV
,
Fischer K
,
Ho E
,
Williams DE
,
Dashwood RH
. 2017.
Divergent roles of p120-catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen-induced rat skin tumors.
.
Mol Carcinog. 56(7):1733-1742.
Comet Assay
Mastaloudis A
,
Yu T-W
,
O'Donnell RP
,
Frei B
,
Dashwood RH
,
Traber MG
. 2004.
Endurance exercise results in DNA damage as detected by the comet assay.
.
Free Radic Biol Med. 36(8):966-75.
Computer Simulation
Parasramka MA
,
W Dashwood M
,
Wang R
,
Abdelli A
,
Bailey GS
,
Williams DE
,
Ho E
,
Dashwood RH
. 2012.
MicroRNA profiling of carcinogen-induced rat colon tumors and the influence of dietary spinach.
.
Mol Nutr Food Res. 56(8):1259-69.
Consensus Sequence
Blum CA
,
Tanaka T
,
Zhong X
,
Li Q
,
Dashwood W-M
,
Pereira C
,
Xu M
,
Dashwood RH
. 2003.
Mutational analysis of Ctnnb1 and Apc in tumors from rats given 1,2-dimethylhydrazine or 2-amino-3-methylimidazo[4,5-f]quinoline: mutational 'hotspots' and the relative expression of beta-catenin and c-jun.
.
Mol Carcinog. 36(4):195-203.
Cyclin D1
Wang R
,
W Dashwood M
,
Bailey GS
,
Williams DE
,
Dashwood RH
. 2006.
Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in beta-catenin that are independent of beta-catenin mutation status.
.
Mutat Res. 601(1-2):11-8.
Cyclin-Dependent Kinase Inhibitor p21
Nian H
,
Delage B
,
Pinto JT
,
Dashwood RH
. 2008.
Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter.
.
Carcinogenesis. 29(9):1816-24.
Myzak MC
,
P Karplus A
,
Chung F-L
,
Dashwood RH
. 2004.
A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.
.
Cancer Res. 64(16):5767-74.
Beaver LM
,
Yu T-W
,
Sokolowski EI
,
Williams DE
,
Dashwood RH
,
Ho E
. 2012.
3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.
.
Toxicol Appl Pharmacol. 263(3):345-51.
Cyclins
Myzak MC
,
P Karplus A
,
Chung F-L
,
Dashwood RH
. 2004.
A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.
.
Cancer Res. 64(16):5767-74.
Cytochrome c Group
G Díaz D
,
Li Q
,
Dashwood RH
. 2003.
Caspase-8 and apoptosis-inducing factor mediate a cytochrome c-independent pathway of apoptosis in human colon cancer cells induced by the dietary phytochemical chlorophyllin.
.
Cancer Res. 63(6):1254-61.
Cytochrome P-450 CYP1A1
Dashwood RH
. 2002.
Modulation of heterocyclic amine-induced mutagenicity and carcinogenicity: an 'A-to-Z' guide to chemopreventive agents, promoters, and transgenic models.
.
Mutat Res. 511(2):89-112.
Yu T-W
,
Xu M
,
Dashwood RH
. 2004.
Antimutagenic activity of spearmint.
.
Environ Mol Mutagen. 44(5):387-93.
Cytochrome P-450 CYP1B1
Madeen EP
,
Löhr CV
,
You H
,
Siddens LK
,
Krueger SK
,
Dashwood RH
,
Gonzalez FJ
,
Baird WM
,
Ho E
,
Bramer L
et al.
. 2017.
Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.
.
Mol Carcinog. 56(1):163-171.
Cytochrome P-450 Enzyme System
Yu T-W
,
Xu M
,
Dashwood RH
. 2004.
Antimutagenic activity of spearmint.
.
Environ Mol Mutagen. 44(5):387-93.
Cytoskeletal Proteins
Orner GA
,
Dashwood W-M
,
Blum CA
,
G Díaz D
,
Li Q
,
Al-Fageeh M
,
Tebbutt N
,
Heath JK
,
Ernst M
,
Dashwood RH
. 2002.
Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
.
Mutat Res. 506-507:121-7.
Myzak MC
,
P Karplus A
,
Chung F-L
,
Dashwood RH
. 2004.
A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.
.
Cancer Res. 64(16):5767-74.
Li Q
,
Dixon BM
,
Al-Fageeh M
,
Blum CA
,
Dashwood RH
. 2002.
Sequencing of the rat beta-catenin gene (Ctnnb1) and mutational analysis of liver tumors induced by 2-amino-3-methylimidazo[4,5-f]quinoline.
.
Gene. 283(1-2):255-62.
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