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About the LPI
Faculty and Staff
Our Research
Micronutrient Information
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Biblio
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Dashwood, Roderick H
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3
Beaver LM
,
Yu T-W
,
Sokolowski EI
,
Williams DE
,
Dashwood RH
,
Ho E
. 2012.
3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.
.
Toxicol Appl Pharmacol. 263(3):345-51.
A
Li Q
,
Dashwood RH
. 2004.
Activator protein 2alpha associates with adenomatous polyposis coli/beta-catenin and Inhibits beta-catenin/T-cell factor transcriptional activity in colorectal cancer cells.
.
J Biol Chem. 279(44):45669-75.
Li Q
,
Löhr CV
,
Dashwood RH
. 2009.
Activator protein 2alpha suppresses intestinal tumorigenesis in the Apc(min) mouse.
.
Cancer Lett. 283(1):36-42.
Li Q
,
Luo C
,
Löhr CV
,
Dashwood RH
. 2011.
Activator protein-2α functions as a master regulator of multiple transcription factors in the mouse liver.
.
Hepatol Res. 41(8):776-83.
Nian H
,
Delage B
,
Pinto JT
,
Dashwood RH
. 2008.
Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter.
.
Carcinogenesis. 29(9):1816-24.
Watson GW
,
Wickramasekara S
,
Fang Y
,
Palomera-Sanchez Z
,
Maier CS
,
Williams DE
,
Dashwood RH
,
Perez VI
,
Ho E
. 2015.
Analysis of autophagic flux in response to sulforaphane in metastatic prostate cancer cells.
.
Mol Nutr Food Res. 59(10):1954-61.
Yu T-W
,
Xu M
,
Dashwood RH
. 2004.
Antimutagenic activity of spearmint.
.
Environ Mol Mutagen. 44(5):387-93.
Watson GW
,
Wickramasekara S
,
Maier CS
,
Williams DE
,
Dashwood RH
,
Ho E
. 2015.
Assessment of global proteome in LNCaP cells by 2D-RP/RP LC-MS/MS following sulforaphane exposure.
.
EuPA Open Proteom. 9:34-40.
B
Wang R
,
W Dashwood M
,
Löhr CV
,
Fischer KA
,
Nakagama H
,
Williams DE
,
Dashwood RH
. 2008.
beta-catenin is strongly elevated in rat colonic epithelium following short-term intermittent treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and a high-fat diet.
.
Cancer Sci. 99(9):1754-9.
Beaver LM
,
Lӧhr CV
,
Clarke JD
,
Glasser ST
,
Watson GW
,
Wong CP
,
Zhang Z
,
Williams DE
,
Dashwood RH
,
Shannon J
et al.
. 2018.
Broccoli Sprouts Delay Prostate Cancer Formation and Decrease Prostate Cancer Severity with a Concurrent Decrease in HDAC3 Protein Expression in Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) Mice.
.
Curr Dev Nutr. 2(3):nzy002.
C
McQuistan TJ
,
Simonich MT
,
M Pratt M
,
Pereira CB
,
Hendricks JD
,
Dashwood RH
,
Williams DE
,
Bailey GS
. 2012.
Cancer chemoprevention by dietary chlorophylls: a 12,000-animal dose-dose matrix biomarker and tumor study.
.
Food Chem Toxicol. 50(2):341-52.
G Díaz D
,
Li Q
,
Dashwood RH
. 2003.
Caspase-8 and apoptosis-inducing factor mediate a cytochrome c-independent pathway of apoptosis in human colon cancer cells induced by the dietary phytochemical chlorophyllin.
.
Cancer Res. 63(6):1254-61.
Myzak MC
,
Dashwood RH
. 2006.
Chemoprotection by sulforaphane: keep one eye beyond Keap1.
.
Cancer Lett. 233(2):208-18.
Li Q
,
Dashwood W-M
,
Zhong X
,
Al-Fageeh M
,
Dashwood RH
. 2004.
Cloning of the rat beta-catenin gene (Ctnnb1) promoter and its functional analysis compared with the Catnb and CTNNB1 promoters.
.
Genomics. 83(2):231-42.
Higdon JV
,
Delage B
,
Williams DE
,
Dashwood RH
. 2007.
Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis.
.
Pharmacol Res. 55(3):224-36.
D
Madeen EP
,
Löhr CV
,
You H
,
Siddens LK
,
Krueger SK
,
Dashwood RH
,
Gonzalez FJ
,
Baird WM
,
Ho E
,
Bramer L
et al.
. 2017.
Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.
.
Mol Carcinog. 56(1):163-171.
Myzak MC
,
Ho E
,
Dashwood RH
. 2006.
Dietary agents as histone deacetylase inhibitors.
.
Mol Carcinog. 45(6):443-6.
Dashwood RH
,
Ho E
. 2008.
Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates.
.
Nutr Rev. 66 Suppl 1:S36-8.
Ho E
,
Beaver LM
,
Williams DE
,
Dashwood RH
. 2011.
Dietary factors and epigenetic regulation for prostate cancer prevention.
.
Adv Nutr. 2(6):497-510.
Delage B
,
Dashwood RH
. 2008.
Dietary manipulation of histone structure and function.
.
Annu Rev Nutr. 28:347-66.
Carter O
,
Bailey GS
,
Dashwood RH
. 2004.
The dietary phytochemical chlorophyllin alters E-cadherin and beta-catenin expression in human colon cancer cells.
.
J Nutr. 134(12 Suppl):3441S-3444S.
Rajendran P
,
Ho E
,
Williams DE
,
Dashwood RH
. 2011.
Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells.
.
Clin Epigenetics. 3(1):4.
Wang R
,
Chen Y-S
,
Dashwood W-M
,
Li Q
,
Löhr CV
,
Fischer K
,
Ho E
,
Williams DE
,
Dashwood RH
. 2017.
Divergent roles of p120-catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen-induced rat skin tumors.
.
Mol Carcinog. 56(7):1733-1742.
E
Chimploy K
,
G Díaz D
,
Li Q
,
Carter O
,
Dashwood W-M
,
Mathews CK
,
Williams DE
,
Bailey GS
,
Dashwood RH
. 2009.
E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin.
.
Int J Cancer. 125(9):2086-94.
Wong CP
,
Hsu A
,
Buchanan A
,
Palomera-Sanchez Z
,
Beaver LM
,
E Houseman A
,
Williams DE
,
Dashwood RH
,
Ho E
. 2014.
Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells.
.
PLoS One. 9(1):e86787.
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