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Found 93 results
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Perez, Viviana I
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Ubiquitination
Pride H
,
Yu Z
,
Sunchu B
,
Mochnick J
,
Coles A
,
Zhang Y
,
Buffenstein R
,
Hornsby PJ
,
Austad SN
,
Perez VI
. 2015.
Long-lived species have improved proteostasis compared to phylogenetically-related shorter-lived species.
.
Biochem Biophys Res Commun. 457(4):669-75.
Transcriptome
Fok WC
,
Chen Y
,
Bokov A
,
Zhang Y
,
Salmon AB
,
Diaz V
,
Javors M
,
Wood WH
,
Zhang Y
,
Becker KG
et al.
. 2014.
Mice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptome.
.
PLoS One. 9(1):e83988.
TOR Serine-Threonine Kinases
Wang R
,
Sunchu B
,
Perez VI
. 2017.
Rapamycin and the inhibition of the secretory phenotype.
.
Exp Gerontol. 94:89-92.
Wang R
,
Yu Z
,
Sunchu B
,
Shoaf J
,
Dang I
,
Zhao S
,
Caples K
,
Bradley L
,
Beaver LM
,
Ho E
et al.
. 2017.
Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2-independent mechanism.
.
Aging Cell. 16(3):564-574.
STAT3 Transcription Factor
Wang R
,
Yu Z
,
Sunchu B
,
Shoaf J
,
Dang I
,
Zhao S
,
Caples K
,
Bradley L
,
Beaver LM
,
Ho E
et al.
. 2017.
Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2-independent mechanism.
.
Aging Cell. 16(3):564-574.
Sirolimus
Fok WC
,
Chen Y
,
Bokov A
,
Zhang Y
,
Salmon AB
,
Diaz V
,
Javors M
,
Wood WH
,
Zhang Y
,
Becker KG
et al.
. 2014.
Mice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptome.
.
PLoS One. 9(1):e83988.
Wang R
,
Sunchu B
,
Perez VI
. 2017.
Rapamycin and the inhibition of the secretory phenotype.
.
Exp Gerontol. 94:89-92.
Yu Z
,
Wang R
,
Fok WC
,
Coles A
,
Salmon AB
,
Perez VI
. 2015.
Rapamycin and dietary restriction induce metabolically distinctive changes in mouse liver.
.
J Gerontol A Biol Sci Med Sci. 70(4):410-20.
Wang R
,
Yu Z
,
Sunchu B
,
Shoaf J
,
Dang I
,
Zhao S
,
Caples K
,
Bradley L
,
Beaver LM
,
Ho E
et al.
. 2017.
Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2-independent mechanism.
.
Aging Cell. 16(3):564-574.
Signal Transduction
Fok WC
,
Chen Y
,
Bokov A
,
Zhang Y
,
Salmon AB
,
Diaz V
,
Javors M
,
Wood WH
,
Zhang Y
,
Becker KG
et al.
. 2014.
Mice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptome.
.
PLoS One. 9(1):e83988.
Wang R
,
Sunchu B
,
Perez VI
. 2017.
Rapamycin and the inhibition of the secretory phenotype.
.
Exp Gerontol. 94:89-92.
Wang R
,
Yu Z
,
Sunchu B
,
Shoaf J
,
Dang I
,
Zhao S
,
Caples K
,
Bradley L
,
Beaver LM
,
Ho E
et al.
. 2017.
Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2-independent mechanism.
.
Aging Cell. 16(3):564-574.
Sex Factors
Fok WC
,
Chen Y
,
Bokov A
,
Zhang Y
,
Salmon AB
,
Diaz V
,
Javors M
,
Wood WH
,
Zhang Y
,
Becker KG
et al.
. 2014.
Mice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptome.
.
PLoS One. 9(1):e83988.
Proteolysis
Pride H
,
Yu Z
,
Sunchu B
,
Mochnick J
,
Coles A
,
Zhang Y
,
Buffenstein R
,
Hornsby PJ
,
Austad SN
,
Perez VI
. 2015.
Long-lived species have improved proteostasis compared to phylogenetically-related shorter-lived species.
.
Biochem Biophys Res Commun. 457(4):669-75.
Protein Kinase Inhibitors
Wang R
,
Sunchu B
,
Perez VI
. 2017.
Rapamycin and the inhibition of the secretory phenotype.
.
Exp Gerontol. 94:89-92.
Protein Interaction Mapping
Watson GW
,
Wickramasekara S
,
Fang Y
,
Maier CS
,
Williams DE
,
Dashwood RH
,
Perez VI
,
Ho E
. 2016.
HDAC6 activity is not required for basal autophagic flux in metastatic prostate cancer cells.
.
Exp Biol Med (Maywood). 241(11):1177-85.
Proteasome Endopeptidase Complex
Pride H
,
Yu Z
,
Sunchu B
,
Mochnick J
,
Coles A
,
Zhang Y
,
Buffenstein R
,
Hornsby PJ
,
Austad SN
,
Perez VI
. 2015.
Long-lived species have improved proteostasis compared to phylogenetically-related shorter-lived species.
.
Biochem Biophys Res Commun. 457(4):669-75.
Prostatic Neoplasms
Watson GW
,
Wickramasekara S
,
Fang Y
,
Palomera-Sanchez Z
,
Maier CS
,
Williams DE
,
Dashwood RH
,
Perez VI
,
Ho E
. 2015.
Analysis of autophagic flux in response to sulforaphane in metastatic prostate cancer cells.
.
Mol Nutr Food Res. 59(10):1954-61.
Primary Cell Culture
Wang R
,
Yu Z
,
Sunchu B
,
Shoaf J
,
Dang I
,
Zhao S
,
Caples K
,
Bradley L
,
Beaver LM
,
Ho E
et al.
. 2017.
Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2-independent mechanism.
.
Aging Cell. 16(3):564-574.
Phylogeny
Pride H
,
Yu Z
,
Sunchu B
,
Mochnick J
,
Coles A
,
Zhang Y
,
Buffenstein R
,
Hornsby PJ
,
Austad SN
,
Perez VI
. 2015.
Long-lived species have improved proteostasis compared to phylogenetically-related shorter-lived species.
.
Biochem Biophys Res Commun. 457(4):669-75.
Phenotype
Wang R
,
Yu Z
,
Sunchu B
,
Shoaf J
,
Dang I
,
Zhao S
,
Caples K
,
Bradley L
,
Beaver LM
,
Ho E
et al.
. 2017.
Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2-independent mechanism.
.
Aging Cell. 16(3):564-574.
Wang R
,
Sunchu B
,
Perez VI
. 2017.
Rapamycin and the inhibition of the secretory phenotype.
.
Exp Gerontol. 94:89-92.
Oxidative Stress
Pride H
,
Yu Z
,
Sunchu B
,
Mochnick J
,
Coles A
,
Zhang Y
,
Buffenstein R
,
Hornsby PJ
,
Austad SN
,
Perez VI
. 2015.
Long-lived species have improved proteostasis compared to phylogenetically-related shorter-lived species.
.
Biochem Biophys Res Commun. 457(4):669-75.
NF-E2-Related Factor 2
Wang R
,
Sunchu B
,
Perez VI
. 2017.
Rapamycin and the inhibition of the secretory phenotype.
.
Exp Gerontol. 94:89-92.
Wang R
,
Yu Z
,
Sunchu B
,
Shoaf J
,
Dang I
,
Zhao S
,
Caples K
,
Bradley L
,
Beaver LM
,
Ho E
et al.
. 2017.
Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2-independent mechanism.
.
Aging Cell. 16(3):564-574.
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