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Faculty and Staff
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Micronutrient Information
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alpha-Tocopherol
Traber MG
. 2013.
Mechanisms for the prevention of vitamin E excess.
.
J Lipid Res. 54(9):2295-306.
Traber MG
,
Head B
. 2021.
Vitamin E: How much is enough, too much and why!
.
Free Radic Biol Med. 177:212-225.
Traber MG
,
Siddens LK
,
Leonard SW
,
Schock B
,
Gohil K
,
Krueger SK
,
Cross CE
,
Williams DE
. 2005.
Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets.
.
Free Radic Biol Med. 38(6):773-85.
Mah E
,
Pei R
,
Guo Y
,
Ballard KD
,
Barker T
,
Rogers VE
,
Parker BA
,
Taylor AW
,
Traber MG
,
Volek JS
et al.
. 2013.
γ-Tocopherol-rich supplementation additively improves vascular endothelial function during smoking cessation.
.
Free Radic Biol Med. 65:1291-1299.
Traber MG
. 2024.
Deciphering the enigma of the function of alpha-tocopherol as a vitamin.
.
Free Radic Biol Med. 221:64-74.
Pei R
,
Mah E
,
Leonard SW
,
Traber MG
,
Bruno RS
. 2015.
α-Tocopherol supplementation reduces 5-nitro-γ-tocopherol accumulation by decreasing γ-tocopherol in young adult smokers.
.
Free Radic Res. 49(9):1114-1121.
Traber MG
,
Mah E
,
Leonard SW
,
Bobe G
,
Bruno RS
. 2017.
Metabolic syndrome increases dietary α-tocopherol requirements as assessed using urinary and plasma vitamin E catabolites: a double-blind, crossover clinical trial.
.
Am J Clin Nutr. 105(3):571-579.
Farley SM
,
Leonard SW
,
Taylor AW
,
Birringer M
,
Edson KZ
,
Rettie AE
,
Traber MG
. 2013.
ω-Hydroxylation of phylloquinone by CYP4F2 is not increased by α-tocopherol.
.
Mol Nutr Food Res. 57(10):1785-93.
Lebold KM
,
Kirkwood JS
,
Taylor AW
,
Choi J
,
Barton CL
,
Miller GW
,
La Du J
,
Jump DB
,
Stevens JFrederik
,
Tanguay RL
et al.
. 2013.
Novel liquid chromatography-mass spectrometry method shows that vitamin E deficiency depletes arachidonic and docosahexaenoic acids in zebrafish (Danio rerio) embryos.
.
Redox Biol. 2:105-13.
Bruno RS
,
Leonard SW
,
Li J
,
Bray TM
,
Traber MG
. 2005.
Lower plasma alpha-carboxyethyl-hydroxychroman after deuterium-labeled alpha-tocopherol supplementation suggests decreased vitamin E metabolism in smokers.
.
Am J Clin Nutr. 81(5):1052-9.
Traber MG
. 2010.
Regulation of xenobiotic metabolism, the only signaling function of alpha-tocopherol?
Mol Nutr Food Res. 54(5):661-8.
Iwaniec UT
,
Turner RT
,
Smith BJ
,
Stoecker BJ
,
Rust A
,
Zhang B
,
Vasu VT
,
Gohil K
,
Cross CE
,
Traber MG
. 2013.
Evaluation of long-term vitamin E insufficiency or excess on bone mass, density, and microarchitecture in rodents.
.
Free Radic Biol Med. 65:1209-1214.
Watts EJ
,
Shen Y
,
Lansky EP
,
Nevo E
,
Bobe G
,
Traber MG
. 2015.
High environmental stress yields greater tocotrienol content while changing vitamin e profiles of wild emmer wheat seeds.
.
J Med Food. 18(2):216-23.
Lebold KM
,
Jump DB
,
Miller GW
,
Wright CL
,
Labut EM
,
Barton CL
,
Tanguay RL
,
Traber MG
. 2011.
Vitamin E deficiency decreases long-chain PUFA in zebrafish (Danio rerio).
.
J Nutr. 141(12):2113-8.
Athinarayanan S
,
Wei R
,
Zhang M
,
Bai S
,
Traber MG
,
Yates K
,
Cummings OW
,
Molleston J
,
Liu W
,
Chalasani N
. 2014.
Genetic polymorphism of cytochrome P450 4F2, vitamin E level and histological response in adults and children with nonalcoholic fatty liver disease who participated in PIVENS and TONIC clinical trials.
.
PLoS One. 9(4):e95366.
Traber MG
,
Burton GW
,
Hamilton RL
. 2004.
Vitamin E trafficking.
.
Ann N Y Acad Sci. 1031:1-12.
Mah E
,
Sapper TN
,
Chitchumroonchokchai C
,
Failla ML
,
Schill KE
,
Clinton SK
,
Bobe G
,
Traber MG
,
Bruno RS
. 2015.
α-Tocopherol bioavailability is lower in adults with metabolic syndrome regardless of dairy fat co-ingestion: a randomized, double-blind, crossover trial.
.
Am J Clin Nutr. 102(5):1070-80.
Mustacich DJ
,
Leonard SW
,
Devereaux MW
,
Sokol RJ
,
Traber MG
. 2006.
Alpha-tocopherol regulation of hepatic cytochrome P450s and ABC transporters in rats.
.
Free Radic Biol Med. 41(7):1069-78.
Mustacich DJ
,
Leonard SW
,
Patel NK
,
Traber MG
. 2010.
Alpha-tocopherol beta-oxidation localized to rat liver mitochondria.
.
Free Radic Biol Med. 48(1):73-81.
Farley SM
,
Leonard SW
,
Stevens JF
,
Traber MG
. 2014.
Deuterium-labeled phylloquinone fed to α-tocopherol-injected rats demonstrates sensitivity of low phylloquinone-containing tissues to menaquinone-4 depletion.
.
Mol Nutr Food Res. 58(8):1610-9.
Traber MG
,
Leonard SW
,
Vasu VT
,
Morrissey BM
,
Lei HJohn
,
Atkinson J
,
Cross CE
. 2022.
α-Tocopherol Pharmacokinetics in Adults with Cystic Fibrosis: Benefits of Supplemental Vitamin C Administration.
.
Nutrients. 14(18)
Miller GW
,
Ulatowski L
,
Labut EM
,
Lebold KM
,
Manor D
,
Atkinson J
,
Barton CL
,
Tanguay RL
,
Traber MG
. 2012.
The α-tocopherol transfer protein is essential for vertebrate embryogenesis.
.
PLoS One. 7(10):e47402.
Traber MG
,
Leonard SW
,
Bobe G
,
Fu X
,
Saltzman E
,
Grusak MA
,
Booth SL
. 2015.
α-Tocopherol disappearance rates from plasma depend on lipid concentrations: studies using deuterium-labeled collard greens in younger and older adults.
.
Am J Clin Nutr. 101(4):752-9.
Kirkwood JS
,
Lebold KM
,
Miranda CL
,
Wright CL
,
Miller GW
,
Tanguay RL
,
Barton CL
,
Traber MG
,
Stevens JF
. 2012.
Vitamin C deficiency activates the purine nucleotide cycle in zebrafish.
.
J Biol Chem. 287(6):3833-41.
Traber MG
,
Cross CE
. 2023.
Alpha-Tocopherol from People to Plants Is an Essential Cog in the Metabolic Machinery.
.
Antioxid Redox Signal. 38(10-12):775-791.
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