Linus Pauling Institute

Lytle KA, Wong CP, Jump DB.  2017.  Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr-/- mice.. PLoS One. 12(4):e0173376.

McDougall M, Choi J, Truong L, Tanguay R, Traber MG.  2017.  Vitamin E deficiency during embryogenesis in zebrafish causes lasting metabolic and cognitive impairments despite refeeding adequate diets.. Free Radic Biol Med. 110:250-260.

McDougall M, Choi J, Truong L, Tanguay R, Traber MG.  2017.  Vitamin E deficiency during embryogenesis in zebrafish causes lasting metabolic and cognitive impairments despite refeeding adequate diets.. Free Radic Biol Med. 110:250-260.

Trias E, Ibarburu S, Barreto-Núñez R, Babdor J, Maciel TT, Guillo M, Gros L, Dubreuil P, Díaz-Amarilla P, Cassina P et al..  2016.  Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis.. J Neuroinflammation. 13(1):177.

Johnson LA, Zuloaga KL, Kugelman TL, Mader KS, Morré JT, Zuloaga DG, Weber S, Marzulla T, Mulford A, Button D et al..  2016.  Amelioration of Metabolic Syndrome-Associated Cognitive Impairments in Mice via a Reduction in Dietary Fat Content or Infusion of Non-Diabetic Plasma.. EBioMedicine. 3:26-42.

Williams JR, Trias E, Beilby PR, Lopez NI, Labut EM, C Bradford S, Roberts BR, McAllum EJ, Crouch PJ, Rhoads TW et al..  2016.  Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD(G93A) mice co-expressing the Copper-Chaperone-for-SOD.. Neurobiol Dis. 89:1-9.

Jump DB, Depner CM, Tripathy S, Lytle KA.  2015.  Potential for dietary ω-3 fatty acids to prevent nonalcoholic fatty liver disease and reduce the risk of primary liver cancer.. Adv Nutr. 6(6):694-702.

Lytle KA, Depner CM, Wong CP, Jump DB.  2015.  Docosahexaenoic acid attenuates Western diet-induced hepatic fibrosis in Ldlr-/- mice by targeting the TGFβ-Smad3 pathway.. J Lipid Res. 56(10):1936-46.

Depner CM, Traber MG, Bobe G, Kensicki E, Bohren KM, Milne G, Jump DB.  2013.  A metabolomic analysis of omega-3 fatty acid-mediated attenuation of western diet-induced nonalcoholic steatohepatitis in LDLR-/- mice.. PLoS One. 8(12):e83756.

Michels AJ, Frei B.  2013.  Myths, artifacts, and fatal flaws: identifying limitations and opportunities in vitamin C research.. Nutrients. 5(12):5161-92.

Kirkwood JS, Legette LCL, Miranda CL, Jiang Y, Stevens JF.  2013.  A metabolomics-driven elucidation of the anti-obesity mechanisms of xanthohumol.. J Biol Chem. 288(26):19000-13.

Wei H, Zhang W-J, McMillen TS, Leboeuf RC, Frei B.  2012.  Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice.. Atherosclerosis. 223(2):306-13.

Wei H, Frei B, Beckman JS, Zhang W-J.  2011.  Copper chelation by tetrathiomolybdate inhibits lipopolysaccharide-induced inflammatory responses in vivo.. Am J Physiol Heart Circ Physiol. 301(3):H712-20.

Miller GW, Labut EM, Lebold KM, Floeter A, Tanguay RL, Traber MG.  2012.  Zebrafish (Danio rerio) fed vitamin E-deficient diets produce embryos with increased morphologic abnormalities and mortality.. J Nutr Biochem. 23(5):478-86.

Zhang W-J, Bird KE, McMillen TS, Leboeuf RC, Hagen TM, Frei B.  2008.  Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice.. Circulation. 117(3):421-8.

Ermilova IP, Ermilov VB, Levy M, Ho E, Pereira C, Beckman JS.  2005.  Protection by dietary zinc in ALS mutant G93A SOD transgenic mice.. Neurosci Lett. 379(1):42-6.

Traber MG, Shimoda K, Murakami K, Leonard SW, Enkhbaatar P, Traber LD, Traber DL.  2007.  Burn and smoke inhalation injury in sheep depletes vitamin E: kinetic studies using deuterated tocopherols.. Free Radic Biol Med. 42(9):1421-9.

Dashwood RH.  2003.  Use of transgenic and mutant animal models in the study of heterocyclic amine-induced mutagenesis and carcinogenesis.. J Biochem Mol Biol. 36(1):35-42.

Leonard SW, Terasawa Y, Farese RV, Traber MG.  2002.  Incorporation of deuterated RRR- or all-rac-alpha-tocopherol in plasma and tissues of alpha-tocopherol transfer protein--null mice.. Am J Clin Nutr. 75(3):555-60.

Xu M, Orner GA, Bailey GS, Stoner GD, Horio DT, Dashwood RH.  2001.  Post-initiation effects of chlorophyllin and indole-3-carbinol in rats given 1,2-dimethylhydrazine or 2-amino-3-methyl- imidazo.. Carcinogenesis. 22(2):309-14.

Carr AC, Zhu BZ, Frei B.  2000.  Potential antiatherogenic mechanisms of ascorbate (vitamin C) and alpha-tocopherol (vitamin E).. Circ Res. 87(5):349-54.

Dunham WB, Young M, Tsao CS.  1994.  Interference by bedding materials in animal test systems involving ascorbic acid depletion.. Lab Anim Sci. 44(3):283-5.

Hilton JBW, Kysenius K, Liddell JR, Mercer SW, Paul B, Beckman JS, McLean CA, White AR, Donnelly PS, Bush AI et al..  2024.  Evidence for disrupted copper availability in human spinal cord supports Cu(atsm) as a treatment option for sporadic cases of ALS.. Sci Rep. 14(1):5929.

Liddell JR, Hilton JBW, Kysenius K, Billings JL, Nikseresht S, McInnes LE, Hare DJ, Paul B, Mercer SW, Belaidi AA et al..  2024.  Microglial ferroptotic stress causes non-cell autonomous neuronal death.. Mol Neurodegener. 19(1):14.

Padiadpu J, Garcia-Jaramillo M, Newman NK, Pederson JW, Rodrigues R, Li Z, Singh S, Monnier P, Trinchieri G, Brown K et al..  2023.  Multi-omic network analysis identified betacellulin as a novel target of omega-3 fatty acid attenuation of western diet-induced nonalcoholic steatohepatitis.. EMBO Mol Med. 15(11):e18367.