Found 26 results
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Cells, Cultured
Kim MJin, Vargas MR, Harlan BA, Killoy KM, Ball LE, Comte-Walters S, Gooz M, Yamamoto Y, Beckman JS, Barbeito L et al..  2018.  Nitration and Glycation Turn Mature NGF into a Toxic Factor for Motor Neurons: A Role for p75 and RAGE Signaling in ALS.. Antioxid Redox Signal. 28(18):1587-1602.
Li C, Zhang W-J, Choi J, Frei B.  2016.  Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase.. Redox Biol. 9:220-228.
Smith EJ, Shay KP, Thomas NO, Butler JA, Finlay LF, Hagen TM.  2015.  Age-related loss of hepatic Nrf2 protein homeostasis: Potential role for heightened expression of miR-146a.. Free Radic Biol Med. 89:1184-91.
Joshi AD, Carter DE, Harper TA, Elferink CJ.  2015.  Aryl hydrocarbon receptor-dependent stanniocalcin 2 induction by cinnabarinic acid provides cytoprotection against endoplasmic reticulum and oxidative stress.. J Pharmacol Exp Ther. 353(1):201-12.
Wong CP, Rinaldi NA, Ho E.  2015.  Zinc deficiency enhanced inflammatory response by increasing immune cell activation and inducing IL6 promoter demethylation.. Mol Nutr Food Res. 59(5):991-9.
Pride H, Yu Z, Sunchu B, Mochnick J, Coles A, Zhang Y, Buffenstein R, Hornsby PJ, Austad SN, Perez VI.  2015.  Long-lived species have improved proteostasis compared to phylogenetically-related shorter-lived species.. Biochem Biophys Res Commun. 457(4):669-75.
Lowry MB, Guo C, Borregaard N, Gombart AF.  2014.  Regulation of the human cathelicidin antimicrobial peptide gene by 1α,25-dihydroxyvitamin D3 in primary immune cells.. J Steroid Biochem Mol Biol. 143:183-91.
Warnock JJ, Bobe G, Duesterdieck-Zellmer KF, Spina J, Ott J, Baltzer WI, Bay BK.  2014.  Growth factor treated tensioned synoviocyte neotissues: towards meniscal bioscaffold tissue engineering.. Vet J. 200(1):22-30.
Wong CP, Hsu A, Buchanan A, Palomera-Sanchez Z, Beaver LM, E Houseman A, Williams DE, Dashwood RH, Ho E.  2014.  Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells.. PLoS One. 9(1):e86787.
Shay KPetersen, Smith EJ, Hagen TM.  2010.  Transcription factor Nrf2: examination of nuclear protein levels by immunoblotting and promoter response element binding by chromatin immunoprecipitation (ChIP).. Curr Protoc Toxicol. Chapter 17:Unit17.13.
Peluso MR, Miranda CL, Hobbs DJ, Proteau RR, Stevens JFrederik.  2010.  Xanthohumol and related prenylated flavonoids inhibit inflammatory cytokine production in LPS-activated THP-1 monocytes: structure-activity relationships and in silico binding to myeloid differentiation protein-2 (MD-2).. Planta Med. 76(14):1536-43.
Shenvi SV, Smith EJ, Hagen TM.  2009.  Transcriptional regulation of rat gamma-glutamate cysteine ligase catalytic subunit gene is mediated through a distal antioxidant response element.. Pharmacol Res. 60(4):229-36.
Li L, Frei B.  2009.  Prolonged exposure to LPS increases iron, heme, and p22phox levels and NADPH oxidase activity in human aortic endothelial cells: inhibition by desferrioxamine.. Arterioscler Thromb Vasc Biol. 29(5):732-8.
Shay KPetersen, Hagen TM.  2009.  Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A.. Biogerontology. 10(4):443-56.
Robinson KM, Janes MS, Pehar M, Monette JS, Ross MF, Hagen TM, Murphy MP, Beckman JS.  2006.  Selective fluorescent imaging of superoxide in vivo using ethidium-based probes.. Proc Natl Acad Sci U S A. 103(41):15038-43.
Lotito SB, Frei B.  2006.  Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism.. J Biol Chem. 281(48):37102-10.
Smith AR, Visioli F, Hagen TM.  2006.  Plasma membrane-associated endothelial nitric oxide synthase and activity in aging rat aortic vascular endothelia markedly decline with age.. Arch Biochem Biophys. 454(1):100-5.
Zhang W-J, Frei B.  2002.  Albumin selectively inhibits TNF alpha-induced expression of vascular cell adhesion molecule-1 in human aortic endothelial cells.. Cardiovasc Res. 55(4):820-9.
Smith AR, Visioli F, Hagen TM.  2002.  Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid.. FASEB J. 16(9):1102-4.
Suh JH, Shigeno ET, Morrow JD, Cox B, Rocha AE, Frei B, Hagen TM.  2001.  Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)-(alpha)-lipoic acid.. FASEB J. 15(3):700-6.
Carr AC, Zhu BZ, Frei B.  2000.  Potential antiatherogenic mechanisms of ascorbate (vitamin C) and alpha-tocopherol (vitamin E).. Circ Res. 87(5):349-54.
Lotito SB, Zhang W-J, Yang CS, Crozier A, Frei B.  2011.  Metabolic conversion of dietary flavonoids alters their anti-inflammatory and antioxidant properties.. Free Radic Biol Med. 51(2):454-63.
Kovacs M, Trias E, Varela V, Ibarburu S, Beckman JS, Moura IC, Hermine O, King PH, Si Y, Kwon Y et al..  2019.  CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS.. Int J Mol Sci. 20(16)
Leung PY, Miyashita K, Young M, Tsao CS.  1993.  Cytotoxic effect of ascorbate and its derivatives on cultured malignant and nonmalignant cell lines.. Anticancer Res. 13(2):475-80.
Harakeh S, Jariwalla RJ.  1991.  Comparative study of the anti-HIV activities of ascorbate and thiol-containing reducing agents in chronically HIV-infected cells.. Am J Clin Nutr. 54(6 Suppl):1231S-1235S.

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