Linus Pauling Institute

Atwell LL, Zhang Z, Mori M, Farris P, Vetto JT, Naik AM, Oh KY, Thuillier P, Ho E, Shannon J.  2015.  Sulforaphane Bioavailability and Chemopreventive Activity in Women Scheduled for Breast Biopsy.. Cancer Prev Res (Phila). 8(12):1184-1191.

Beaver LM, Kuintzle R, Buchanan A, Wiley MW, Glasser ST, Wong CP, Johnson GS, Chang JH, Löhr CV, Williams DE et al..  2017.  Long noncoding RNAs and sulforaphane: a target for chemoprevention and suppression of prostate cancer.. J Nutr Biochem. 42:72-83.

Beaver LM, Yu T-W, Sokolowski EI, Williams DE, Dashwood RH, Ho E.  2012.  3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.. Toxicol Appl Pharmacol. 263(3):345-51.

Blum CA, Xu M, Orner GA, G Díaz D, Li Q, Dashwood WMohaiza, Bailey GS, Dashwood RH.  2003.  Promotion versus suppression of rat colon carcinogenesis by chlorophyllin and chlorophyll: modulation of apoptosis, cell proliferation, and beta-catenin/Tcf signaling.. Mutat Res. 523-524:217-23.

Blum CA, Xu M, Orner GA, Fong AT, Bailey GS, Stoner GD, Horio DT, Dashwood RH.  2001.  beta-Catenin mutation in rat colon tumors initiated by 1,2-dimethylhydrazine and 2-amino-3-methylimidazo[4,5-f]quinoline, and the effect of post-initiation treatment with chlorophyllin and indole-3-carbinol.. Carcinogenesis. 22(2):315-20.

Chimploy K, G Díaz D, Li Q, Carter O, Dashwood W-M, Mathews CK, Williams DE, Bailey GS, Dashwood RH.  2009.  E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin.. Int J Cancer. 125(9):2086-94.

Dashwood RH.  1999.  Early detection and prevention of colorectal cancer (review).. Oncol Rep. 6(2):277-81.

Dashwood RH.  2002.  Modulation of heterocyclic amine-induced mutagenicity and carcinogenicity: an 'A-to-Z' guide to chemopreventive agents, promoters, and transgenic models.. Mutat Res. 511(2):89-112.

Dashwood RH.  2006.  Xenobiotic metabolism relevance to cancer.. J Nutr. 136(10):2681S-2S.

Dashwood W-M, Orner GA, Dashwood RH.  2002.  Inhibition of beta-catenin/Tcf activity by white tea, green tea, and epigallocatechin-3-gallate (EGCG): minor contribution of H(2)O(2) at physiologically relevant EGCG concentrations.. Biochem Biophys Res Commun. 296(3):584-8.

Dashwood RH, Ho E.  2008.  Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates.. Nutr Rev. 66 Suppl 1:S36-8.

Dashwood W-M, Carter O, Al-Fageeh M, Li Q, Dashwood RH.  2005.  Lysosomal trafficking of beta-catenin induced by the tea polyphenol epigallocatechin-3-gallate.. Mutat Res. 591(1-2):161-72.

G Díaz D, Li Q, Dashwood RH.  2003.  Caspase-8 and apoptosis-inducing factor mediate a cytochrome c-independent pathway of apoptosis in human colon cancer cells induced by the dietary phytochemical chlorophyllin.. Cancer Res. 63(6):1254-61.

Higdon JV, Frei B.  2005.  Is there a gender difference in the effect of antioxidants on cancer risk? Br J Nutr. 94(2):139-40.

Higdon JV, Delage B, Williams DE, Dashwood RH.  2007.  Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis.. Pharmacol Res. 55(3):224-36.

Johnson GS, Li J, Beaver LM, W Dashwood M, Sun D, Rajendran P, Williams DE, Ho E, Dashwood RH.  2017.  A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a coactivator of NQO1 in sulforaphane-treated colon cancer cells.. Mol Nutr Food Res. 61(4)

Krueger SK, VanDyke JE, Williams DE, Hines RN.  2006.  The role of flavin-containing monooxygenase (FMO) in the metabolism of tamoxifen and other tertiary amines.. Drug Metab Rev. 38(1-2):139-47.

Larsen CA, Dashwood RH, Bisson WH.  2010.  Tea catechins as inhibitors of receptor tyrosine kinases: mechanistic insights and human relevance.. Pharmacol Res. 62(6):457-64.

Myzak MC, P Karplus A, Chung F-L, Dashwood RH.  2004.  A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.. Cancer Res. 64(16):5767-74.

Myzak MC, Hardin K, Wang R, Dashwood RH, Ho E.  2006.  Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells.. Carcinogenesis. 27(4):811-9.

Myzak MC, Dashwood RH.  2006.  Chemoprotection by sulforaphane: keep one eye beyond Keap1.. Cancer Lett. 233(2):208-18.

Myzak MC, Dashwood RH.  2006.  Histone deacetylases as targets for dietary cancer preventive agents: lessons learned with butyrate, diallyl disulfide, and sulforaphane.. Curr Drug Targets. 7(4):443-52.

Nian H, Delage B, Ho E, Dashwood RH.  2009.  Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds.. Environ Mol Mutagen. 50(3):213-21.

Orner GA, Dashwood W-M, Dashwood RH.  2004.  Tumor-suppressing effects of antioxidants from tea.. J Nutr. 134(11):3177S-3178S.

Parasramka MA, Ho E, Williams DE, Dashwood RH.  2012.  MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals.. Mol Carcinog. 51(3):213-30.