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Faculty and Staff
Our Research
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Biblio
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Anticarcinogenic Agents
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Anticarcinogenic Agents
Beaver LM
,
Kuintzle R
,
Buchanan A
,
Wiley MW
,
Glasser ST
,
Wong CP
,
Johnson GS
,
Chang JH
,
Löhr CV
,
Williams DE
et al.
. 2017.
Long noncoding RNAs and sulforaphane: a target for chemoprevention and suppression of prostate cancer.
.
J Nutr Biochem. 42:72-83.
Johnson GS
,
Li J
,
Beaver LM
,
W Dashwood M
,
Sun D
,
Rajendran P
,
Williams DE
,
Ho E
,
Dashwood RH
. 2017.
A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a coactivator of NQO1 in sulforaphane-treated colon cancer cells.
.
Mol Nutr Food Res. 61(4)
Thomson CA
,
Ho E
,
Strom MB
. 2016.
Chemopreventive properties of 3,3'-diindolylmethane in breast cancer: evidence from experimental and human studies.
.
Nutr Rev. 74(7):432-43.
Atwell LL
,
Zhang Z
,
Mori M
,
Farris P
,
Vetto JT
,
Naik AM
,
Oh KY
,
Thuillier P
,
Ho E
,
Shannon J
. 2015.
Sulforaphane Bioavailability and Chemopreventive Activity in Women Scheduled for Breast Biopsy.
.
Cancer Prev Res (Phila). 8(12):1184-1191.
Perera T
,
Young MR
,
Zhang Z
,
Murphy G
,
Colburn NH
,
Lanza E
,
Hartman TJ
,
Cross AJ
,
Bobe G
. 2015.
Identification and monitoring of metabolite markers of dry bean consumption in parallel human and mouse studies.
.
Mol Nutr Food Res. 59(4):795-806.
Wong CP
,
Hsu A
,
Buchanan A
,
Palomera-Sanchez Z
,
Beaver LM
,
E Houseman A
,
Williams DE
,
Dashwood RH
,
Ho E
. 2014.
Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells.
.
PLoS One. 9(1):e86787.
Beaver LM
,
Yu T-W
,
Sokolowski EI
,
Williams DE
,
Dashwood RH
,
Ho E
. 2012.
3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.
.
Toxicol Appl Pharmacol. 263(3):345-51.
Parasramka MA
,
Ho E
,
Williams DE
,
Dashwood RH
. 2012.
MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals.
.
Mol Carcinog. 51(3):213-30.
Larsen CA
,
Dashwood RH
,
Bisson WH
. 2010.
Tea catechins as inhibitors of receptor tyrosine kinases: mechanistic insights and human relevance.
.
Pharmacol Res. 62(6):457-64.
Chimploy K
,
G Díaz D
,
Li Q
,
Carter O
,
Dashwood W-M
,
Mathews CK
,
Williams DE
,
Bailey GS
,
Dashwood RH
. 2009.
E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin.
.
Int J Cancer. 125(9):2086-94.
Wang R
,
W Dashwood M
,
Löhr CV
,
Fischer KA
,
Pereira CB
,
Louderback M
,
Nakagama H
,
Bailey GS
,
Williams DE
,
Dashwood RH
. 2008.
Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat.
.
Carcinogenesis. 29(4):834-9.
Dashwood RH
,
Ho E
. 2008.
Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates.
.
Nutr Rev. 66 Suppl 1:S36-8.
Nian H
,
Delage B
,
Ho E
,
Dashwood RH
. 2009.
Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds.
.
Environ Mol Mutagen. 50(3):213-21.
Myzak MC
,
Hardin K
,
Wang R
,
Dashwood RH
,
Ho E
. 2006.
Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells.
.
Carcinogenesis. 27(4):811-9.
Higdon JV
,
Frei B
. 2005.
Is there a gender difference in the effect of antioxidants on cancer risk?
Br J Nutr. 94(2):139-40.
Dashwood W-M
,
Carter O
,
Al-Fageeh M
,
Li Q
,
Dashwood RH
. 2005.
Lysosomal trafficking of beta-catenin induced by the tea polyphenol epigallocatechin-3-gallate.
.
Mutat Res. 591(1-2):161-72.
Higdon JV
,
Delage B
,
Williams DE
,
Dashwood RH
. 2007.
Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis.
.
Pharmacol Res. 55(3):224-36.
Dashwood RH
. 2006.
Xenobiotic metabolism relevance to cancer.
.
J Nutr. 136(10):2681S-2S.
Wang R
,
W Dashwood M
,
Bailey GS
,
Williams DE
,
Dashwood RH
. 2006.
Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in beta-catenin that are independent of beta-catenin mutation status.
.
Mutat Res. 601(1-2):11-8.
Krueger SK
,
VanDyke JE
,
Williams DE
,
Hines RN
. 2006.
The role of flavin-containing monooxygenase (FMO) in the metabolism of tamoxifen and other tertiary amines.
.
Drug Metab Rev. 38(1-2):139-47.
Myzak MC
,
Dashwood RH
. 2006.
Histone deacetylases as targets for dietary cancer preventive agents: lessons learned with butyrate, diallyl disulfide, and sulforaphane.
.
Curr Drug Targets. 7(4):443-52.
Myzak MC
,
Dashwood RH
. 2006.
Chemoprotection by sulforaphane: keep one eye beyond Keap1.
.
Cancer Lett. 233(2):208-18.
Orner GA
,
Dashwood W-M
,
Dashwood RH
. 2004.
Tumor-suppressing effects of antioxidants from tea.
.
J Nutr. 134(11):3177S-3178S.
Myzak MC
,
P Karplus A
,
Chung F-L
,
Dashwood RH
. 2004.
A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.
.
Cancer Res. 64(16):5767-74.
G Díaz D
,
Li Q
,
Dashwood RH
. 2003.
Caspase-8 and apoptosis-inducing factor mediate a cytochrome c-independent pathway of apoptosis in human colon cancer cells induced by the dietary phytochemical chlorophyllin.
.
Cancer Res. 63(6):1254-61.
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