Found 23 results
Author [ Keyword(Desc)] Title Type Year
Filters: Keyword is Mice, Knockout  [Clear All Filters]
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Mice, Knockout
Lytle KA, Wong CP, Jump DB.  2017.  Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr-/- mice.. PLoS One. 12(4):e0173376.
Wang R, Yu Z, Sunchu B, Shoaf J, Dang I, Zhao S, Caples K, Bradley L, Beaver LM, Ho E et al..  2017.  Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2-independent mechanism.. Aging Cell. 16(3):564-574.
Madeen EP, Löhr CV, You H, Siddens LK, Krueger SK, Dashwood RH, Gonzalez FJ, Baird WM, Ho E, Bramer L et al..  2017.  Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.. Mol Carcinog. 56(1):163-171.
Lytle KA, Jump DB.  2016.  Is Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr-/- Mice Reversible? PLoS One. 11(1):e0146942.
Jump DB, Depner CM, Tripathy S, Lytle KA.  2015.  Potential for dietary ω-3 fatty acids to prevent nonalcoholic fatty liver disease and reduce the risk of primary liver cancer.. Adv Nutr. 6(6):694-702.
Lytle KA, Depner CM, Wong CP, Jump DB.  2015.  Docosahexaenoic acid attenuates Western diet-induced hepatic fibrosis in Ldlr-/- mice by targeting the TGFβ-Smad3 pathway.. J Lipid Res. 56(10):1936-46.
Siddens LK, Bunde KL, Harper TA, McQuistan TJ, Löhr CV, Bramer LM, Waters KM, Tilton SC, Krueger SK, Williams DE et al..  2015.  Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse.. Toxicol Appl Pharmacol. 287(2):149-160.
Harper TA, Morré J, Lauer FT, McQuistan TJ, Hummel JM, Burchiel SW, Williams DE.  2015.  Analysis of dibenzo[def,p]chrysene-deoxyadenosine adducts in wild-type and cytochrome P450 1b1 knockout mice using stable-isotope dilution UHPLC-MS/MS.. Mutat Res Genet Toxicol Environ Mutagen. 782:51-6.
Joshi AD, Carter DE, Harper TA, Elferink CJ.  2015.  Aryl hydrocarbon receptor-dependent stanniocalcin 2 induction by cinnabarinic acid provides cytoprotection against endoplasmic reticulum and oxidative stress.. J Pharmacol Exp Ther. 353(1):201-12.
Okamoto R, Gery S, Gombart AF, Wang X, Castellani LW, Akagi T, Chen S, Arditi M, Ho Q, Lusis AJ et al..  2014.  Deficiency of CCAAT/enhancer binding protein-epsilon reduces atherosclerotic lesions in LDLR-/- mice.. PLoS One. 9(1):e85341.
Depner CM, Traber MG, Bobe G, Kensicki E, Bohren KM, Milne G, Jump DB.  2013.  A metabolomic analysis of omega-3 fatty acid-mediated attenuation of western diet-induced nonalcoholic steatohepatitis in LDLR-/- mice.. PLoS One. 8(12):e83756.
Iwaniec UT, Turner RT, Smith BJ, Stoecker BJ, Rust A, Zhang B, Vasu VT, Gohil K, Cross CE, Traber MG.  2013.  Evaluation of long-term vitamin E insufficiency or excess on bone mass, density, and microarchitecture in rodents.. Free Radic Biol Med. 65:1209-1214.
Depner CM, Torres-Gonzalez M, Tripathy S, Milne G, Jump DB.  2012.  Menhaden oil decreases high-fat diet-induced markers of hepatic damage, steatosis, inflammation, and fibrosis in obese Ldlr-/- mice.. J Nutr. 142(8):1495-503.
Wei H, Zhang W-J, McMillen TS, Leboeuf RC, Frei B.  2012.  Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice.. Atherosclerosis. 223(2):306-13.
Traber MG, Mustacich DJ, Sullivan LC, Leonard SW, Ahern-Rindell A, Kerkvliet N.  2010.  Vitamin E status and metabolism in adult and aged aryl hydrocarbon receptor null mice.. J Nutr Biochem. 21(12):1193-9.
Li Q, Löhr CV, Dashwood RH.  2009.  Activator protein 2alpha suppresses intestinal tumorigenesis in the Apc(min) mouse.. Cancer Lett. 283(1):36-42.
Zhang W-J, Wei H, Frei B.  2009.  Genetic deficiency of NADPH oxidase does not diminish, but rather enhances, LPS-induced acute inflammatory responses in vivo.. Free Radic Biol Med. 46(6):791-8.
Myzak MC, W Dashwood M, Orner GA, Ho E, Dashwood RH.  2006.  Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice.. FASEB J. 20(3):506-8.
Lim Y, Schock BC, Gohil K, Leonard SW, Packer L, Cross CE, Traber MG.  2004.  Gene-nutrient interactions exemplified by the alpha-tocopherol content of tissues from alpha-tocopherol transfer protein-null mice fed different dietary vitamin E concentrations.. Ann N Y Acad Sci. 1031:328-9.
Dashwood RH.  2003.  Use of transgenic and mutant animal models in the study of heterocyclic amine-induced mutagenesis and carcinogenesis.. J Biochem Mol Biol. 36(1):35-42.
Beckman JS, Esétvez AG, Barbeito L, Crow JP.  2002.  CCS knockout mice establish an alternative source of copper for SOD in ALS.. Free Radic Biol Med. 33(10):1433-5.
Leonard SW, Terasawa Y, Farese RV, Traber MG.  2002.  Incorporation of deuterated RRR- or all-rac-alpha-tocopherol in plasma and tissues of alpha-tocopherol transfer protein--null mice.. Am J Clin Nutr. 75(3):555-60.
Zhang W-J, Wei H, Tien Y-T, Frei B.  2011.  Genetic ablation of phagocytic NADPH oxidase in mice limits TNFα-induced inflammation in the lungs but not other tissues.. Free Radic Biol Med. 50(11):1517-25.