Found 13 results
Author [ Keyword(Desc)] Title Type Year
Filters: Author is Dashwood, Roderick H and Keyword is Histone Deacetylase Inhibitors  [Clear All Filters]
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Histone Deacetylase Inhibitors
Rajendran P, Kidane AI, Yu T-W, Dashwood W-M, Bisson WH, Löhr CV, Ho E, Williams DE, Dashwood RH.  2013.  HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates.. Epigenetics. 8(6):612-23.
Beaver LM, Yu T-W, Sokolowski EI, Williams DE, Dashwood RH, Ho E.  2012.  3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.. Toxicol Appl Pharmacol. 263(3):345-51.
Nian H, Delage B, Pinto JT, Dashwood RH.  2008.  Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter.. Carcinogenesis. 29(9):1816-24.
Dashwood RH, Ho E.  2008.  Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates.. Nutr Rev. 66 Suppl 1:S36-8.
Nian H, Delage B, Ho E, Dashwood RH.  2009.  Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds.. Environ Mol Mutagen. 50(3):213-21.
Myzak MC, W Dashwood M, Orner GA, Ho E, Dashwood RH.  2006.  Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice.. FASEB J. 20(3):506-8.
Myzak MC, Hardin K, Wang R, Dashwood RH, Ho E.  2006.  Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells.. Carcinogenesis. 27(4):811-9.
Myzak MC, Tong P, Dashwood W-M, Dashwood RH, Ho E.  2007.  Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects.. Exp Biol Med (Maywood). 232(2):227-34.
Dashwood RH.  2006.  Xenobiotic metabolism relevance to cancer.. J Nutr. 136(10):2681S-2S.
Myzak MC, Ho E, Dashwood RH.  2006.  Dietary agents as histone deacetylase inhibitors.. Mol Carcinog. 45(6):443-6.
Myzak MC, Dashwood RH.  2006.  Histone deacetylases as targets for dietary cancer preventive agents: lessons learned with butyrate, diallyl disulfide, and sulforaphane.. Curr Drug Targets. 7(4):443-52.
Myzak MC, P Karplus A, Chung F-L, Dashwood RH.  2004.  A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.. Cancer Res. 64(16):5767-74.
Rajendran P, Williams DE, Ho E, Dashwood RH.  2011.  Metabolism as a key to histone deacetylase inhibition.. Crit Rev Biochem Mol Biol. 46(3):181-99.