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Faculty and Staff
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Biblio
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Flavonoids
Zamzow DR
,
Elias V
,
Legette LCL
,
Choi J
,
J Stevens F
,
Magnusson KR
. 2014.
Xanthohumol improved cognitive flexibility in young mice.
.
Behav Brain Res. 275:1-10.
Yang L
,
Broderick D
,
Campbell Y
,
Gombart AF
,
Stevens JF
,
Jiang Y
,
Hsu VL
,
Bisson WH
,
Maier CS
. 2016.
Conformational modulation of the farnesoid X receptor by prenylflavonoids: Insights from hydrogen deuterium exchange mass spectrometry (HDX-MS), fluorescence titration and molecular docking studies.
.
Biochim Biophys Acta. 1864(12):1667-1677.
Lela L
,
Ponticelli M
,
Carlucci V
,
Stevens JF
,
Faraone I
,
Tzvetkov NT
,
Milella L
. 2024.
Insight into the Interaction of L. Specialized Metabolites and Gastrointestinal Bitter Taste Receptors: Study in STC-1 Cells and Molecular Docking.
.
J Nat Prod. 87(8):2021-2033.
Legette LC
,
Ma L
,
Reed RL
,
Miranda CL
,
Christensen JMark
,
Rodriguez-Proteau R
,
Stevens JF
. 2012.
Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.
.
Mol Nutr Food Res. 56(3):466-74.
Logan IE
,
Shulzhenko N
,
Sharpton TJ
,
Bobe G
,
Liu K
,
Nuss S
,
Jones ML
,
Miranda CL
,
Vasquez-Perez S
,
Pennington JM
et al.
. 2021.
Xanthohumol Requires the Intestinal Microbiota to Improve Glucose Metabolism in Diet-Induced Obese Mice.
.
Mol Nutr Food Res. 65(21):e2100389.
Peluso MR
,
Miranda CL
,
Hobbs DJ
,
Proteau RR
,
Stevens JFrederik
. 2010.
Xanthohumol and related prenylated flavonoids inhibit inflammatory cytokine production in LPS-activated THP-1 monocytes: structure-activity relationships and in silico binding to myeloid differentiation protein-2 (MD-2).
.
Planta Med. 76(14):1536-43.
Legette LCL
,
Luna AYMoreno
,
Reed RL
,
Miranda CL
,
Bobe G
,
Proteau RR
,
Stevens JF
. 2013.
Xanthohumol lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats.
.
Phytochemistry. 91:236-41.
Lotito SB
,
Frei B
. 2006.
Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon?
Free Radic Biol Med. 41(12):1727-46.
Kirkwood JS
,
Maier C
,
Stevens JF
. 2013.
Simultaneous, untargeted metabolic profiling of polar and nonpolar metabolites by LC-Q-TOF mass spectrometry.
.
Curr Protoc Toxicol. Chapter 4:Unit4.39.
Larsen CA
,
Bisson WH
,
Dashwood RH
. 2009.
Tea catechins inhibit hepatocyte growth factor receptor (MET kinase) activity in human colon cancer cells: kinetic and molecular docking studies.
.
J Med Chem. 52(21):6543-5.
Stevens JF
,
Page JE
. 2004.
Xanthohumol and related prenylflavonoids from hops and beer: to your good health!
.
Phytochemistry. 65(10):1317-30.
Lotito SB
,
Zhang W-J
,
Yang CS
,
Crozier A
,
Frei B
. 2011.
Metabolic conversion of dietary flavonoids alters their anti-inflammatory and antioxidant properties.
.
Free Radic Biol Med. 51(2):454-63.
Jamieson PE
,
Smart EB
,
Bouranis JA
,
Choi J
,
Danczak RE
,
Wong CP
,
Paraiso IL
,
Maier CS
,
Ho E
,
Sharpton TJ
et al.
. 2024.
Gut enterotype-dependent modulation of gut microbiota and their metabolism in response to xanthohumol supplementation in healthy adults.
.
Gut Microbes. 16(1):2315633.
Kirkwood JS
,
Legette LCL
,
Miranda CL
,
Jiang Y
,
Stevens JF
. 2013.
A metabolomics-driven elucidation of the anti-obesity mechanisms of xanthohumol.
.
J Biol Chem. 288(26):19000-13.
Kesinger NG
,
Stevens JF
. 2009.
Covalent interaction of ascorbic acid with natural products.
.
Phytochemistry. 70(17-18):1930-9.
Lotito SB
,
Frei B
. 2004.
Relevance of apple polyphenols as antioxidants in human plasma: contrasting in vitro and in vivo effects.
.
Free Radic Biol Med. 36(2):201-11.
Zheljazkov VD
,
Semerdjieva IB
,
Borisova D
,
Yankova-Tsvetkova E
,
Koleva-Valkova LH
,
Petrova G
,
Dincheva I
,
Stevens F
,
Wu W
,
Astatkie T
et al.
. 2023.
Phytochemical and biological investigations on Centranthus kellereri (Stoj., Stef. & T. Georgiev) Stoj. & Stef. and C. ruber (L.) DC. and their potential as new medicinal and ornamental plants.
.
PLoS One. 18(11):e0293877.
Lotito SB
,
Frei B
. 2006.
Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism.
.
J Biol Chem. 281(48):37102-10.
Higdon JV
,
Frei B
. 2003.
Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions.
.
Crit Rev Food Sci Nutr. 43(1):89-143.
Flow Cytometry
Zhang W-J
,
Frei B
. 2002.
Albumin selectively inhibits TNF alpha-induced expression of vascular cell adhesion molecule-1 in human aortic endothelial cells.
.
Cardiovasc Res. 55(4):820-9.
Lowry MB
,
Guo C
,
Borregaard N
,
Gombart AF
. 2014.
Regulation of the human cathelicidin antimicrobial peptide gene by 1α,25-dihydroxyvitamin D3 in primary immune cells.
.
J Steroid Biochem Mol Biol. 143:183-91.
Nian H
,
Delage B
,
Pinto JT
,
Dashwood RH
. 2008.
Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter.
.
Carcinogenesis. 29(9):1816-24.
Fluorescein
Roemeling MD
,
Williams J
,
Beckman JS
,
Hurst JK
. 2015.
Imidazole catalyzes chlorination by unreactive primary chloramines.
.
Free Radic Biol Med. 82:167-78.
Fluoresceins
Hagen TM
,
Liu J
,
Lykkesfeldt J
,
Wehr CM
,
Ingersoll RT
,
Vinarsky V
,
Bartholomew JC
,
Ames BN
. 2002.
Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress.
.
Proc Natl Acad Sci U S A. 99(4):1870-5.
Miranda CL
,
Reed RL
,
Kuiper HC
,
Alber S
,
Stevens JF
. 2009.
Ascorbic acid promotes detoxification and elimination of 4-hydroxy-2(E)-nonenal in human monocytic THP-1 cells.
.
Chem Res Toxicol. 22(5):863-74.
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