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Oxidative Stress
Ivanov V, Carr AC, Frei B.  2001.  Red wine antioxidants bind to human lipoproteins and protect them from metal ion-dependent and -independent oxidation.. J Agric Food Chem. 49(9):4442-9.
Shay KPetersen, Moreau RF, Smith EJ, Hagen TM.  2008.  Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity. IUBMB Life. 60(6):362-7.
Matsumoto S, Traber MG, Leonard SW, Choi J, Fang X, Maishan M, Wick KD, Jones KD, Calfee CS, Gotts JE et al..  2022.  Aerosolized vitamin E acetate causes oxidative injury in mice and in alveolar macrophages.. Am J Physiol Lung Cell Mol Physiol. 322(6):L771-L783.
Traber MG.  2007.  Heart disease and single-vitamin supplementation.. Am J Clin Nutr. 85(1):293S-299S.
Traber MG, Buettner GR, Bruno RS.  2019.  The relationship between vitamin C status, the gut-liver axis, and metabolic syndrome.. Redox Biol. 21:101091.
Song Y, Chung CS, Bruno RS, Traber MG, Brown KH, King JC, Ho E.  2009.  Dietary zinc restriction and repletion affects DNA integrity in healthy men.. Am J Clin Nutr. 90(2):321-8.
Suh JH, Shigeno ET, Morrow JD, Cox B, Rocha AE, Frei B, Hagen TM.  2001.  Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)-(alpha)-lipoic acid.. FASEB J. 15(3):700-6.
Taylor AW, Bruno RS, Traber MG.  2008.  Women and smokers have elevated urinary F(2)-isoprostane metabolites: a novel extraction and LC-MS methodology.. Lipids. 43(10):925-36.
Forman HJay, Traber M, Ursini F.  2014.  Antioxidants: GRABbing new headlines.. Free Radic Biol Med. 66:1-2.
Bruno RS, Traber MG.  2005.  Cigarette smoke alters human vitamin E requirements.. J Nutr. 135(4):671-4.
Jump DB, Depner CM, Tripathy S, Lytle KA.  2015.  Potential for dietary ω-3 fatty acids to prevent nonalcoholic fatty liver disease and reduce the risk of primary liver cancer.. Adv Nutr. 6(6):694-702.
Frei B, Birlouez-Aragon I, Lykkesfeldt J.  2012.  Authors' perspective: What is the optimum intake of vitamin C in humans? Crit Rev Food Sci Nutr. 52(9):815-29.
Li L, Frei B.  2006.  Iron chelation inhibits NF-kappaB-mediated adhesion molecule expression by inhibiting p22(phox) protein expression and NADPH oxidase activity.. Arterioscler Thromb Vasc Biol. 26(12):2638-43.
Li L, Smith A, Hagen TM, Frei B.  2010.  Vascular oxidative stress and inflammation increase with age: ameliorating effects of alpha-lipoic acid supplementation.. Ann N Y Acad Sci. 1203:151-9.
Kuiper HC, Stevens JF.  2011.  LC-MS/MS quantitation of mercapturic acid conjugates of lipid peroxidation products as markers of oxidative stress.. Curr Protoc Toxicol. Chapter 17:Unit17.14.2.
Kirkwood JS, Legette LCL, Miranda CL, Jiang Y, Stevens JF.  2013.  A metabolomics-driven elucidation of the anti-obesity mechanisms of xanthohumol.. J Biol Chem. 288(26):19000-13.
Hagen TM, Liu J, Lykkesfeldt J, Wehr CM, Ingersoll RT, Vinarsky V, Bartholomew JC, Ames BN.  2002.  Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress.. Proc Natl Acad Sci U S A. 99(4):1870-5.
McDougall M, Choi J, Truong L, Tanguay R, Traber MG.  2017.  Vitamin E deficiency during embryogenesis in zebrafish causes lasting metabolic and cognitive impairments despite refeeding adequate diets.. Free Radic Biol Med. 110:250-260.
Li C, Zhang W-J, Choi J, Frei B.  2016.  Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase.. Redox Biol. 9:220-228.
Visioli F, Ingram A, Beckman JS, Magnusson KR, Hagen TM.  2022.  Strategies to protect against age-related mitochondrial decay: Do natural products and their derivatives help? Free Radic Biol Med. 178:330-346.
Higdon JV, Frei B.  2003.  Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions.. Crit Rev Food Sci Nutr. 43(1):89-143.
Depner CM, Traber MG, Bobe G, Kensicki E, Bohren KM, Milne G, Jump DB.  2013.  A metabolomic analysis of omega-3 fatty acid-mediated attenuation of western diet-induced nonalcoholic steatohepatitis in LDLR-/- mice.. PLoS One. 8(12):e83756.
Bruno RS, Leonard SW, Li J, Bray TM, Traber MG.  2005.  Lower plasma alpha-carboxyethyl-hydroxychroman after deuterium-labeled alpha-tocopherol supplementation suggests decreased vitamin E metabolism in smokers.. Am J Clin Nutr. 81(5):1052-9.
Lytle KA, Jump DB.  2016.  Is Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr-/- Mice Reversible? PLoS One. 11(1):e0146942.
Smith AR, Visioli F, Hagen TM.  2002.  Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid.. FASEB J. 16(9):1102-4.

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