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Found 6340 results
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Aging
Gómez LA
,
Hagen TM
. 2012.
Age-related decline in mitochondrial bioenergetics: does supercomplex destabilization determine lower oxidative capacity and higher superoxide production?
Semin Cell Dev Biol. 23(7):758-67.
Suh JH
,
Moreau R
,
Heath S-HD
,
Hagen TM
. 2005.
Dietary supplementation with (R)-alpha-lipoic acid reverses the age-related accumulation of iron and depletion of antioxidants in the rat cerebral cortex.
.
Redox Rep. 10(1):52-60.
Wong CP
,
Rinaldi NA
,
Ho E
. 2015.
Zinc deficiency enhanced inflammatory response by increasing immune cell activation and inducing IL6 promoter demethylation.
.
Mol Nutr Food Res. 59(5):991-9.
Shay KPetersen
,
Hagen TM
. 2009.
Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A.
.
Biogerontology. 10(4):443-56.
Zamzow DR
,
Elias V
,
Legette LCL
,
Choi J
,
J Stevens F
,
Magnusson KR
. 2014.
Xanthohumol improved cognitive flexibility in young mice.
.
Behav Brain Res. 275:1-10.
Suh JH
,
Shigeno ET
,
Morrow JD
,
Cox B
,
Rocha AE
,
Frei B
,
Hagen TM
. 2001.
Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)-(alpha)-lipoic acid.
.
FASEB J. 15(3):700-6.
Smith AR
,
Visioli F
,
Frei B
,
Hagen TM
. 2006.
Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A.
.
Aging Cell. 5(5):391-400.
Smith AR
,
Visioli F
,
Frei B
,
Hagen TM
. 2008.
Lipoic acid significantly restores, in rats, the age-related decline in vasomotion.
.
Br J Pharmacol. 153(8):1615-22.
Smith AR
,
Visioli F
,
Hagen TM
. 2006.
Plasma membrane-associated endothelial nitric oxide synthase and activity in aging rat aortic vascular endothelia markedly decline with age.
.
Arch Biochem Biophys. 454(1):100-5.
Moreau R
,
Heath S-HD
,
Doneanu CE
,
J Lindsay G
,
Hagen TM
. 2003.
Age-related increase in 4-hydroxynonenal adduction to rat heart alpha-ketoglutarate dehydrogenase does not cause loss of its catalytic activity.
.
Antioxid Redox Signal. 5(5):517-27.
Suh JH
,
Shenvi SV
,
Dixon BM
,
Liu H
,
Jaiswal AK
,
Liu R-M
,
Hagen TM
. 2004.
Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid.
.
Proc Natl Acad Sci U S A. 101(10):3381-6.
Thomas NO
,
Shay KP
,
Kelley AR
,
Butler JA
,
Hagen TM
. 2016.
Glutathione maintenance mitigates age-related susceptibility to redox cycling agents.
.
Redox Biol. 10:45-52.
Suh JH
,
Heath S-H
,
Hagen TM
. 2003.
Two subpopulations of mitochondria in the aging rat heart display heterogenous levels of oxidative stress.
.
Free Radic Biol Med. 35(9):1064-72.
Fleming JE
,
Reveillaud I
,
Niedzwiecki A
. 1992.
Role of oxidative stress in Drosophila aging.
.
Mutat Res. 275(3-6):267-79.
Hagen TM
,
Moreau R
,
Suh JH
,
Visioli F
. 2002.
Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid.
.
Ann N Y Acad Sci. 959:491-507.
Iwaniec UT
,
Turner RT
,
Smith BJ
,
Stoecker BJ
,
Rust A
,
Zhang B
,
Vasu VT
,
Gohil K
,
Cross CE
,
Traber MG
. 2013.
Evaluation of long-term vitamin E insufficiency or excess on bone mass, density, and microarchitecture in rodents.
.
Free Radic Biol Med. 65:1209-1214.
Moreau R
,
Heath S-HD
,
Doneanu CE
,
Harris RA
,
Hagen TM
. 2004.
Age-related compensatory activation of pyruvate dehydrogenase complex in rat heart.
.
Biochem Biophys Res Commun. 325(1):48-58.
Michels AJ
,
Joisher N
,
Hagen TM
. 2003.
Age-related decline of sodium-dependent ascorbic acid transport in isolated rat hepatocytes.
.
Arch Biochem Biophys. 410(1):112-20.
Niedzwiecki A
,
Reveillaud I
,
Fleming JE
. 1992.
Changes in superoxide dismutase and catalase in aging heat-shocked Drosophila.
.
Free Radic Res Commun. 17(6):355-67.
Moreau R
,
Nguyen BT
,
Doneanu CE
,
Hagen TM
. 2005.
Reversal by aminoguanidine of the age-related increase in glycoxidation and lipoxidation in the cardiovascular system of Fischer 344 rats.
.
Biochem Pharmacol. 69(1):29-40.
Smith EJ
,
Shay KP
,
Thomas NO
,
Butler JA
,
Finlay LF
,
Hagen TM
. 2015.
Age-related loss of hepatic Nrf2 protein homeostasis: Potential role for heightened expression of miR-146a.
.
Free Radic Biol Med. 89:1184-91.
Smith AR
,
Hagen TM
. 2003.
Vascular endothelial dysfunction in aging: loss of Akt-dependent endothelial nitric oxide synthase phosphorylation and partial restoration by (R)-alpha-lipoic acid.
.
Biochem Soc Trans. 31(Pt 6):1447-9.
Wang R
,
Yu Z
,
Sunchu B
,
Shoaf J
,
Dang I
,
Zhao S
,
Caples K
,
Bradley L
,
Beaver LM
,
Ho E
et al.
. 2017.
Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2-independent mechanism.
.
Aging Cell. 16(3):564-574.
Alanine Transaminase
Netke SP
,
Roomi MW
,
Tsao C
,
Niedzwiecki A
. 1997.
Ascorbic acid protects guinea pigs from acute aflatoxin toxicity.
.
Toxicol Appl Pharmacol. 143(2):429-35.
Albumins
Kubglomsong S
,
Theerakulkait C
,
Reed RL
,
Yang L
,
Maier CS
,
Stevens JF
. 2018.
Isolation and Identification of Tyrosinase-Inhibitory and Copper-Chelating Peptides from Hydrolyzed Rice-Bran-Derived Albumin.
.
J Agric Food Chem. 66(31):8346-8354.
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