Linus Pauling Institute

Zhang W-J, Wei H, Frei B.  2010.  The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice.. Exp Biol Med (Maywood). 235(5):633-41.

Li L, Frei B.  2006.  Iron chelation inhibits NF-kappaB-mediated adhesion molecule expression by inhibiting p22(phox) protein expression and NADPH oxidase activity.. Arterioscler Thromb Vasc Biol. 26(12):2638-43.

Zhang WJian, Frei B.  2003.  Intracellular metal ion chelators inhibit TNFalpha-induced SP-1 activation and adhesion molecule expression in human aortic endothelial cells.. Free Radic Biol Med. 34(6):674-82.

Lotito SB, Frei B.  2004.  The increase in human plasma antioxidant capacity after apple consumption is due to the metabolic effect of fructose on urate, not apple-derived antioxidant flavonoids.. Free Radic Biol Med. 37(2):251-8.

Carr AC, Frei B.  2002.  Human neutrophils oxidize low-density lipoprotein by a hypochlorous acid-dependent mechanism: the role of vitamin C.. Biol Chem. 383(3-4):627-36.

Michels AJ, Hagen TM, Frei B.  2013.  Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme function.. Annu Rev Nutr. 33:45-70.

Yilmazer-Musa M, Griffith AM, Michels AJ, Schneider E, Frei B.  2012.  Grape seed and tea extracts and catechin 3-gallates are potent inhibitors of α-amylase and α-glucosidase activity.. J Agric Food Chem. 60(36):8924-9.

Zhang W-J, Wei H, Frei B.  2009.  Genetic deficiency of NADPH oxidase does not diminish, but rather enhances, LPS-induced acute inflammatory responses in vivo.. Free Radic Biol Med. 46(6):791-8.

Zhang W-J, Wei H, Tien Y-T, Frei B.  2011.  Genetic ablation of phagocytic NADPH oxidase in mice limits TNFα-induced inflammation in the lungs but not other tissues.. Free Radic Biol Med. 50(11):1517-25.

Mastaloudis A, Yu T-W, O'Donnell RP, Frei B, Dashwood RH, Traber MG.  2004.  Endurance exercise results in DNA damage as detected by the comet assay.. Free Radic Biol Med. 36(8):966-75.

Lotito SB, Frei B.  2006.  Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism.. J Biol Chem. 281(48):37102-10.

Zhang W-J, Bird KE, McMillen TS, Leboeuf RC, Hagen TM, Frei B.  2008.  Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice.. Circulation. 117(3):421-8.

Michels AJ, Leonard SW, Uesugi SL, Bobe G, Frei B, Traber MG.  2018.  Daily Consumption of Oregon Hazelnuts Affects α-Tocopherol Status in Healthy Older Adults: A Pre-Post Intervention Study.. J Nutr. 148(12):1924-1930.

Wei H, Zhang W-J, McMillen TS, Leboeuf RC, Frei B.  2012.  Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice.. Atherosclerosis. 223(2):306-13.

Wei H, Frei B, Beckman JS, Zhang W-J.  2011.  Copper chelation by tetrathiomolybdate inhibits lipopolysaccharide-induced inflammatory responses in vivo.. Am J Physiol Heart Circ Physiol. 301(3):H712-20.

Blumberg JB, Frei B, Fulgoni VL, Weaver CM, Zeisel SH.  2017.  Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups.. Nutrients. 9(12)

Blumberg JB, Frei B, Fulgoni VL, Weaver CM, Zeisel SH.  2017.  Contribution of Dietary Supplements to Nutritional Adequacy in Race/Ethnic Population Subgroups in the United States.. Nutrients. 9(12)

Blumberg JB, Frei B, Fulgoni VL, Weaver CM, Zeisel SH.  2017.  Contribution of Dietary Supplements to Nutritional Adequacy by Socioeconomic Subgroups in Adults of the United States.. Nutrients. 10(1)

Lotito SB, Frei B.  2006.  Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon? Free Radic Biol Med. 41(12):1727-46.

Higdon JV, Frei B.  2006.  Coffee and health: a review of recent human research.. Crit Rev Food Sci Nutr. 46(2):101-23.

Taylor AW, Bruno RS, Frei B, Traber MG.  2006.  Benefits of prolonged gradient separation for high-performance liquid chromatography-tandem mass spectrometry quantitation of plasma total 15-series F-isoprostanes.. Anal Biochem. 350(1):41-51.

Frei B, Birlouez-Aragon I, Lykkesfeldt J.  2012.  Authors' perspective: What is the optimum intake of vitamin C in humans? Crit Rev Food Sci Nutr. 52(9):815-29.

Zhang W-J, Frei B.  2015.  Astragaloside IV inhibits NF- κ B activation and inflammatory gene expression in LPS-treated mice.. Mediators Inflamm. 2015:274314.

Kerr DCR, Zava DT, Piper WT, Saturn SR, Frei B, Gombart AF.  2015.  Associations between vitamin D levels and depressive symptoms in healthy young adult women.. Psychiatry Res. 227(1):46-51.

Zhang W-J, Wei H, Hagen T, Frei B.  2007.  Alpha-lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway.. Proc Natl Acad Sci U S A. 104(10):4077-82.