Linus Pauling Institute

Hagen TM, Moreau R, Suh JH, Visioli F.  2002.  Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid.. Ann N Y Acad Sci. 959:491-507.

Carr A, Frei B.  2000.  The role of natural antioxidants in preserving the biological activity of endothelium-derived nitric oxide.. Free Radic Biol Med. 28(12):1806-14.

Zhang W-J, Wei H, Hagen T, Frei B.  2007.  Alpha-lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway.. Proc Natl Acad Sci U S A. 104(10):4077-82.

Song Y, Chung CS, Bruno RS, Traber MG, Brown KH, King JC, Ho E.  2009.  Dietary zinc restriction and repletion affects DNA integrity in healthy men.. Am J Clin Nutr. 90(2):321-8.

Traber MG, Buettner GR, Bruno RS.  2019.  The relationship between vitamin C status, the gut-liver axis, and metabolic syndrome.. Redox Biol. 21:101091.

Ivanov V, Carr AC, Frei B.  2001.  Red wine antioxidants bind to human lipoproteins and protect them from metal ion-dependent and -independent oxidation.. J Agric Food Chem. 49(9):4442-9.

Lee Y, Drake AC, Thomas NO, Ferguson LG, Chappell PE, Shay KPetersen.  2018.  Dietary resveratrol increases mid-life fecundity of female Nothobranchius guentheri.. Comp Biochem Physiol C Toxicol Pharmacol. 208:71-76.

Lotito SB, Frei B.  2006.  Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism.. J Biol Chem. 281(48):37102-10.

Keith DJ, Butler JA, Bemer B, Dixon B, Johnson S, Garrard M, Sudakin DL, J Christensen M, Pereira C, Hagen TM.  2012.  Age and gender dependent bioavailability of R- and R,S-α-lipoic acid: a pilot study.. Pharmacol Res. 66(3):199-206.

Cadenas E, Packer L, Traber MG.  2016.  Antioxidants, oxidants, and redox impacts on cell function - A tribute to Helmut Sies.. Arch Biochem Biophys. 595:94-9.

Traber MG, van der Vliet A, Reznick AZ, Cross CE.  2000.  Tobacco-related diseases. Is there a role for antioxidant micronutrient supplementation? Clin Chest Med. 21(1):173-87,x.

Traber MG.  2001.  Does vitamin E decrease heart attack risk? summary and implications with respect to dietary recommendations. J Nutr. 131(2):395S-7S.

Suh JH, Shenvi SV, Dixon BM, Liu H, Jaiswal AK, Liu R-M, Hagen TM.  2004.  Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid.. Proc Natl Acad Sci U S A. 101(10):3381-6.

Lebold KM, Traber MG.  2014.  Interactions between α-tocopherol, polyunsaturated fatty acids, and lipoxygenases during embryogenesis.. Free Radic Biol Med. 66:13-9.

Traber MG, Stevens JF.  2011.  Vitamins C and E: beneficial effects from a mechanistic perspective.. Free Radic Biol Med. 51(5):1000-13.

Lotito SB, Zhang W-J, Yang CS, Crozier A, Frei B.  2011.  Metabolic conversion of dietary flavonoids alters their anti-inflammatory and antioxidant properties.. Free Radic Biol Med. 51(2):454-63.

Bruno RS, Leonard SW, Li J, Bray TM, Traber MG.  2005.  Lower plasma alpha-carboxyethyl-hydroxychroman after deuterium-labeled alpha-tocopherol supplementation suggests decreased vitamin E metabolism in smokers.. Am J Clin Nutr. 81(5):1052-9.

Mah E, Sapper TN, Chitchumroonchokchai C, Failla ML, Schill KE, Clinton SK, Bobe G, Traber MG, Bruno RS.  2015.  α-Tocopherol bioavailability is lower in adults with metabolic syndrome regardless of dairy fat co-ingestion: a randomized, double-blind, crossover trial.. Am J Clin Nutr. 102(5):1070-80.

Suh JH, Heath S-H, Hagen TM.  2003.  Two subpopulations of mitochondria in the aging rat heart display heterogenous levels of oxidative stress.. Free Radic Biol Med. 35(9):1064-72.

Brigelius-Flohé R, Traber MG.  1999.  Vitamin E: function and metabolism.. FASEB J. 13(10):1145-55.

Wattanasiritham L, Theerakulkait C, Wickramasekara S, Maier CS, Stevens JF.  2016.  Isolation and identification of antioxidant peptides from enzymatically hydrolyzed rice bran protein.. Food Chem. 192:156-62.

Carr AC, McCall MR, Frei B.  2000.  Oxidation of LDL by myeloperoxidase and reactive nitrogen species: reaction pathways and antioxidant protection.. Arterioscler Thromb Vasc Biol. 20(7):1716-23.

Shay KPetersen, Hagen TM.  2009.  Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A.. Biogerontology. 10(4):443-56.

Frei B, McCall MR.  2001.  Antioxidant vitamins: evidence from biomarkers in humans.. Bibl Nutr Dieta. (55):46-67.

Carpenter EL, Wyant MB, Indra A, Ito S, Wakamatsu K, Merrill GF, Moos PJ, Cassidy PB, Leachman SA, Ganguli-Indra G et al..  2022.  Thioredoxin Reductase 1 Modulates Pigmentation and Photobiology of Murine Melanocytes in vivo.. J Invest Dermatol. 142(7):1903-1911.e5.