Linus Pauling Institute

Jamieson PE, Smart EB, Bouranis JA, Choi J, Danczak RE, Wong CP, Paraiso IL, Maier CS, Ho E, Sharpton TJ et al..  2024.  Gut enterotype-dependent modulation of gut microbiota and their metabolism in response to xanthohumol supplementation in healthy adults.. Gut Microbes. 16(1):2315633.

Magana AAlcazar, Vaswani A, Brown KS, Jiang Y, Alam MNure, Caruso M, Lak P, Cheong P, Gray NE, Quinn JF et al..  2024.  Integrating High-Resolution Mass Spectral Data, Bioassays and Computational Models to Annotate Bioactives in Botanical Extracts: Case Study Analysis of Extract Associates Dicaffeoylquinic Acids with Protection against Amyloid-β Toxicity.. Molecules. 29(4)

Yang L, Choi J, Maier CS, Stevens JF.  2024.  Profiling of Oxylipins as Markers of Oxidative Stress in Biological Samples.. Curr Protoc. 4(3):e992.

Bouranis JA, Beaver LM, Wong CP, Choi J, Hamer S, Davis EW, Brown KS, Jiang D, Sharpton TJ, Stevens JF et al..  2024.  Sulforaphane and Sulforaphane-Nitrile Metabolism in Humans Following Broccoli Sprout Consumption: Inter-individual Variation, Association with Gut Microbiome Composition, and Differential Bioactivity.. Mol Nutr Food Res. 68(4):e2300286.

Webber LC, Anderson LN, Paraiso IL, Metz TO, Bradley R, Stevens JF, Wright AT.  2023.  Affinity- and activity-based probes synthesized from structurally diverse hops-derived xanthohumol flavonoids reveal highly varied protein profiling in .. RSC Adv. 13(42):29324-29331.

Jamieson PE, Carbonero F, Stevens JF.  2023.  Dietary (poly)phenols mitigate inflammatory bowel disease: Therapeutic targets, mechanisms of action, and clinical observations.. Curr Res Food Sci. 6:100521.

Zheng TJ, Kohs TCL, Mueller PA, Pang J, Reitsma SE, Parra-Izquierdo I, Melrose AR, Yang L, Choi J, Zientek KD et al..  2023.  Effect of antiplatelet agents and tyrosine kinase inhibitors on oxLDL-mediated procoagulant platelet activity.. Blood Adv. 7(8):1366-1378.

Yang L, Marney L, Magana AAlcazar, Choi J, Wright K, Mcferrin J, Gray NE, Soumyanath A, Stevens JF, Maier CS.  2023.  Quantification of Caffeoylquinic Acids and Triterpenes as Targeted Bioactive Compounds of in Extracts and Formulations by Liquid Chromatography Mass Spectrometry.. J Chromatogr Open. 4

Kundu P, Holden S, Paraiso IL, Sudhakar R, McQuesten C, Choi J, Miranda CL, Maier CS, Bobe G, Stevens JF et al..  2022.  ApoE isoform-dependent effects of xanthohumol on high fat diet-induced cognitive impairments and hippocampal metabolic pathways.. Front Pharmacol. 13:954980.

Brown KS, Jamieson P, Wu W, Vaswani A, Magana AAlcazar, Choi J, Mattio LM, Cheong PHa-Yeon, Nelson D, Reardon PN et al..  2022.  Computation-Assisted Identification of Bioactive Compounds in Botanical Extracts: A Case Study of Anti-Inflammatory Natural Products from Hops.. Antioxidants (Basel). 11(7)

Holvoet H, Long DM, Law A, McClure C, Choi J, Yang L, Marney L, Poeck B, Strauss R, Stevens JF et al..  2022.  Extracts Promote Resilience against Age-Related and Stress-Induced Behavioral Phenotypes in a Possible Role of Other Compounds besides Withanolides.. Nutrients. 14(19)

Khorani M, Bobe G, Matthews DG, Magana AAlcazar, Caruso M, Gray NE, Quinn JF, Stevens JF, Soumyanath A, Maier CS.  2022.  The Impact of the hAPP695SW Transgene and Associated Amyloid-β Accumulation on Murine Hippocampal Biochemical Pathways.. J Alzheimers Dis. 85(4):1601-1619.

Bouranis JA, Beaver LM, Jiang D, Choi J, Wong CP, Davis EW, Williams DE, Sharpton TJ, Stevens JF, Ho E.  2022.  Interplay between Cruciferous Vegetables and the Gut Microbiome: A Multi-Omic Approach.. Nutrients. 15(1)

Keller RM, Beaver LM, Prater MC, Truong L, Tanguay RL, Stevens JF, Hord NG.  2022.  Nitrate exposure reprograms hepatic amino acid and nutrient sensing pathways prior to exercise: A metabolomic and transcriptomic investigation in zebrafish .. Front Mol Biosci. 9:903130.

Wright KM, Bollen M, David J, Speers AB, Brandes MS, Gray NE, Magana AAlcazar, McClure C, Stevens JF, Maier CS et al..  2022.  Pharmacokinetics and Pharmacodynamics of Key Components of a Standardized Product in Cognitively Impaired Older Adults: A Phase 1, Double-Blind, Randomized Clinical Trial.. Antioxidants (Basel). 11(2)

Miranda CL, Kumbi Y, Wu W, Lee H-S, Reed RL, Stevens JF.  2022.  Phytochemical characterization and bioactivity toward breast cancer cells of unhydrolyzed and acid-hydrolyzed extracts of .. Nat Prod Commun. 17(7)

Cabey K, Long DM, Law A, Gray NE, McClure C, Caruso M, Lak P, Wright KM, Stevens JF, Maier CS et al..  2022.   Withania somnifera and Centella asiatica Extracts Ameliorate Behavioral Deficits in an In Vivo Drosophila melanogaster Model of Oxidative Stress.. Antioxidants (Basel). 11(1)

Kundu P, Paraiso IL, Choi J, Miranda CL, Kioussi C, Maier CS, Bobe G, Stevens JF, Raber J.  2022.  Xanthohumol improves cognition in farnesoid X receptor-deficient mice on a high-fat diet.. Dis Model Mech. 15(11)

Langley BO, Ryan JJoan, Phipps J, Buttolph L, Bray B, Aslan JE, Metz TO, Stevens JF, Bradley R.  2022.  Xanthohumol microbiome and signature in adults with Crohn's disease (the XMaS trial): a protocol for a phase II triple-masked, placebo-controlled clinical trial.. Trials. 23(1):885.

Speers AB, Garcia-Jaramillo M, Feryn A, Matthews DG, Lichtenberg T, Caruso M, Wright KM, Quinn JF, Stevens JF, Maier CS et al..  2021.  Alters Metabolic Pathways Associated With Alzheimer's Disease in the 5xFAD Mouse Model of -Amyloid Accumulation.. Front Pharmacol. 12:788312.

Magana AAlcazar, Kamimura N, Soumyanath A, Stevens JF, Maier CS.  2021.  Caffeoylquinic acids: Chemistry, biosynthesis, occurrence, analytical challenges, and bioactivity.. Plant J.

Bouranis JA, Beaver LM, Choi J, Wong CP, Jiang D, Sharpton TJ, Stevens JF, Ho E.  2021.  Composition of the Gut Microbiome Influences Production of Sulforaphane-Nitrile and Iberin-Nitrile from Glucosinolates in Broccoli Sprouts.. Nutrients. 13(9)

Wright KM, Mcferrin J, Magana AAlcazar, Roberts J, Caruso M, Kretzschmar D, Stevens JF, Maier CS, Quinn JF, Soumyanath A.  2021.  Developing a Rational, Optimized Product of for Examination in Clinical Trials: Real World Challenges.. Front Nutr. 8:799137.

Zheljazkov VD, Semerdjieva IB, Stevens JF, Wu W, Cantrell CL, Yankova-Tsvetkova E, Koleva-Valkova LH, Stoyanova A, Astatkie T.  2021.  Phytochemical Investigation and Reproductive Capacity of the Bulgarian Endemic Plant Species Boiss. (Lamiaceae).. Plants (Basel). 11(1)

Zhang Y, Bobe G, Miranda CL, Lowry MB, Hsu VL, Löhr CV, Wong CP, Jump DB, Robinson MM, Sharpton TJ et al..  2021.  Tetrahydroxanthohumol, a xanthohumol derivative, attenuates high-fat diet-induced hepatic steatosis by antagonizing PPARγ.. Elife. 10