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Faculty and Staff
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Stevens, Jan F
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Vegetables
Bouranis JA
,
Beaver LM
,
Jiang D
,
Choi J
,
Wong CP
,
Davis EW
,
Williams DE
,
Sharpton TJ
,
Stevens JF
,
Ho E
. 2022.
Interplay between Cruciferous Vegetables and the Gut Microbiome: A Multi-Omic Approach.
.
Nutrients. 15(1)
Uncoupling Protein 1
Kirkwood JS
,
Legette LCL
,
Miranda CL
,
Jiang Y
,
Stevens JF
. 2013.
A metabolomics-driven elucidation of the anti-obesity mechanisms of xanthohumol.
.
J Biol Chem. 288(26):19000-13.
Tyrosine Kinase Inhibitors
Zheng TJ
,
Kohs TCL
,
Mueller PA
,
Pang J
,
Reitsma SE
,
Parra-Izquierdo I
,
Melrose AR
,
Yang L
,
Choi J
,
Zientek KD
et al.
. 2023.
Effect of antiplatelet agents and tyrosine kinase inhibitors on oxLDL-mediated procoagulant platelet activity.
.
Blood Adv. 7(8):1366-1378.
Tumor Cells, Cultured
Miranda CL
,
Reed RL
,
Kuiper HC
,
Alber S
,
Stevens JF
. 2009.
Ascorbic acid promotes detoxification and elimination of 4-hydroxy-2(E)-nonenal in human monocytic THP-1 cells.
.
Chem Res Toxicol. 22(5):863-74.
Trypsin
Wattanasiritham L
,
Theerakulkait C
,
Wickramasekara S
,
Maier CS
,
Stevens JF
. 2016.
Isolation and identification of antioxidant peptides from enzymatically hydrolyzed rice bran protein.
.
Food Chem. 192:156-62.
Triterpenes
Magana AAlcazar
,
Vaswani A
,
Brown KS
,
Jiang Y
,
Alam MNure
,
Caruso M
,
Lak P
,
Cheong P
,
Gray NE
,
Quinn JF
et al.
. 2024.
Integrating High-Resolution Mass Spectral Data, Bioassays and Computational Models to Annotate Bioactives in Botanical Extracts: Case Study Analysis of Extract Associates Dicaffeoylquinic Acids with Protection against Amyloid-β Toxicity.
.
Molecules. 29(4)
Transgenes
Khorani M
,
Bobe G
,
Matthews DG
,
Magana AAlcazar
,
Caruso M
,
Gray NE
,
Quinn JF
,
Stevens JF
,
Soumyanath A
,
Maier CS
. 2022.
The Impact of the hAPP695SW Transgene and Associated Amyloid-β Accumulation on Murine Hippocampal Biochemical Pathways.
.
J Alzheimers Dis. 85(4):1601-1619.
Time Factors
Kirkwood JS
,
Legette LCL
,
Miranda CL
,
Jiang Y
,
Stevens JF
. 2013.
A metabolomics-driven elucidation of the anti-obesity mechanisms of xanthohumol.
.
J Biol Chem. 288(26):19000-13.
Sowell J
,
Frei B
,
Stevens JF
. 2004.
Vitamin C conjugates of genotoxic lipid peroxidation products: structural characterization and detection in human plasma.
.
Proc Natl Acad Sci U S A. 101(52):17964-9.
Thiourea
Henderson MC
,
Krueger SK
,
Stevens JF
,
Williams DE
. 2004.
Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione.
.
Chem Res Toxicol. 17(5):633-40.
Thiocyanates
Bouranis JA
,
Beaver LM
,
Choi J
,
Wong CP
,
Jiang D
,
Sharpton TJ
,
Stevens JF
,
Ho E
. 2021.
Composition of the Gut Microbiome Influences Production of Sulforaphane-Nitrile and Iberin-Nitrile from Glucosinolates in Broccoli Sprouts.
.
Nutrients. 13(9)
tau Proteins
Gray NE
,
Morré J
,
Kelley J
,
Maier CS
,
Stevens JF
,
Quinn JF
,
Soumyanath A
. 2014.
Caffeoylquinic acids in Centella asiatica protect against amyloid-β toxicity.
.
J Alzheimers Dis. 40(2):359-73.
Tandem Mass Spectrometry
Legette LC
,
Ma L
,
Reed RL
,
Miranda CL
,
Christensen JMark
,
Rodriguez-Proteau R
,
Stevens JF
. 2012.
Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.
.
Mol Nutr Food Res. 56(3):466-74.
Elie MR
,
Choi J
,
Nkrumah-Elie YM
,
Gonnerman GD
,
Stevens JF
,
Tanguay RL
. 2015.
Metabolomic analysis to define and compare the effects of PAHs and oxygenated PAHs in developing zebrafish.
.
Environ Res. 140:502-10.
Legette LC
,
Karnpracha C
,
Reed RL
,
Choi J
,
Bobe G
,
J Christensen M
,
Rodriguez-Proteau R
,
Purnell JQ
,
Stevens JF
. 2014.
Human pharmacokinetics of xanthohumol, an antihyperglycemic flavonoid from hops.
.
Mol Nutr Food Res. 58(2):248-55.
Axton ER
,
Hardardt EA
,
Stevens JF
. 2016.
Stable isotope-assisted LC-MS/MS monitoring of glyceryl trinitrate bioactivation in a cell culture model of nitrate tolerance.
.
J Chromatogr B Analyt Technol Biomed Life Sci. 1019:156-63.
Kuiper HC
,
Stevens JF
. 2011.
LC-MS/MS quantitation of mercapturic acid conjugates of lipid peroxidation products as markers of oxidative stress.
.
Curr Protoc Toxicol. Chapter 17:Unit17.14.2.
Bouranis JA
,
Beaver LM
,
Jiang D
,
Choi J
,
Wong CP
,
Davis EW
,
Williams DE
,
Sharpton TJ
,
Stevens JF
,
Ho E
. 2022.
Interplay between Cruciferous Vegetables and the Gut Microbiome: A Multi-Omic Approach.
.
Nutrients. 15(1)
Kirkwood JS
,
Maier C
,
Stevens JF
. 2013.
Simultaneous, untargeted metabolic profiling of polar and nonpolar metabolites by LC-Q-TOF mass spectrometry.
.
Curr Protoc Toxicol. Chapter 4:Unit4.39.
Sulfoxides
Bouranis JA
,
Beaver LM
,
Wong CP
,
Choi J
,
Hamer S
,
Davis EW
,
Brown KS
,
Jiang D
,
Sharpton TJ
,
Stevens JF
et al.
. 2024.
Sulforaphane and Sulforaphane-Nitrile Metabolism in Humans Following Broccoli Sprout Consumption: Inter-individual Variation, Association with Gut Microbiome Composition, and Differential Bioactivity.
.
Mol Nutr Food Res. 68(4):e2300286.
Bouranis JA
,
Beaver LM
,
Choi J
,
Wong CP
,
Jiang D
,
Sharpton TJ
,
Stevens JF
,
Ho E
. 2021.
Composition of the Gut Microbiome Influences Production of Sulforaphane-Nitrile and Iberin-Nitrile from Glucosinolates in Broccoli Sprouts.
.
Nutrients. 13(9)
Sulfenic Acids
Henderson MC
,
Krueger SK
,
Stevens JF
,
Williams DE
. 2004.
Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione.
.
Chem Res Toxicol. 17(5):633-40.
Stem Cells
Kirkwood JS
,
Miranda CL
,
Bobe G
,
Maier CS
,
Stevens JF
. 2016.
18O-Tracer Metabolomics Reveals Protein Turnover and CDP-Choline Cycle Activity in Differentiating 3T3-L1 Pre-Adipocytes.
.
PLoS One. 11(6):e0157118.
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Han B
,
Stevens JF
,
Maier CS
. 2007.
Design, synthesis, and application of a hydrazide-functionalized isotope-coded affinity tag for the quantification of oxylipid-protein conjugates.
.
Anal Chem. 79(9):3342-54.
Spectrometry, Mass, Electrospray Ionization
Kuiper HC
,
Stevens JF
. 2011.
LC-MS/MS quantitation of mercapturic acid conjugates of lipid peroxidation products as markers of oxidative stress.
.
Curr Protoc Toxicol. Chapter 17:Unit17.14.2.
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