Linus Pauling Institute

Johnson LA, Torres ERuth S, Impey S, Stevens JF, Raber J.  2017.  Apolipoprotein E4 and Insulin Resistance Interact to Impair Cognition and Alter the Epigenome and Metabolome.. Sci Rep. 7:43701.

Madeen EP, Löhr CV, You H, Siddens LK, Krueger SK, Dashwood RH, Gonzalez FJ, Baird WM, Ho E, Bramer L et al..  2017.  Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.. Mol Carcinog. 56(1):163-171.

Lytle KA, Wong CP, Jump DB.  2017.  Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr-/- mice.. PLoS One. 12(4):e0173376.

Wang R, Yu Z, Sunchu B, Shoaf J, Dang I, Zhao S, Caples K, Bradley L, Beaver LM, Ho E et al..  2017.  Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2-independent mechanism.. Aging Cell. 16(3):564-574.

Kirkwood JS, Miranda CL, Bobe G, Maier CS, Stevens JF.  2016.  18O-Tracer Metabolomics Reveals Protein Turnover and CDP-Choline Cycle Activity in Differentiating 3T3-L1 Pre-Adipocytes.. PLoS One. 11(6):e0157118.

Johnson LA, Zuloaga KL, Kugelman TL, Mader KS, Morré JT, Zuloaga DG, Weber S, Marzulla T, Mulford A, Button D et al..  2016.  Amelioration of Metabolic Syndrome-Associated Cognitive Impairments in Mice via a Reduction in Dietary Fat Content or Infusion of Non-Diabetic Plasma.. EBioMedicine. 3:26-42.

Williams JR, Trias E, Beilby PR, Lopez NI, Labut EM, C Bradford S, Roberts BR, McAllum EJ, Crouch PJ, Rhoads TW et al..  2016.  Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD(G93A) mice co-expressing the Copper-Chaperone-for-SOD.. Neurobiol Dis. 89:1-9.

Chagani S, Kyryachenko S, Yamamoto Y, Kato S, Ganguli-Indra G, Indra AK.  2016.  In Vivo Role of Vitamin D Receptor Signaling in UVB-Induced DNA Damage and Melanocyte Homeostasis.. J Invest Dermatol. 136(10):2108-2111.

Lytle KA, Jump DB.  2016.  Is Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr-/- Mice Reversible? PLoS One. 11(1):e0146942.

Miranda CL, Elias VD, Hay JJ, Choi J, Reed RL, Stevens JF.  2016.  Xanthohumol improves dysfunctional glucose and lipid metabolism in diet-induced obese C57BL/6J mice.. Arch Biochem Biophys. 599:22-30.

Zhang W-J, Frei B.  2015.  Astragaloside IV inhibits NF- κ B activation and inflammatory gene expression in LPS-treated mice.. Mediators Inflamm. 2015:274314.

Siddens LK, Bunde KL, Harper TA, McQuistan TJ, Löhr CV, Bramer LM, Waters KM, Tilton SC, Krueger SK, Williams DE et al..  2015.  Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse.. Toxicol Appl Pharmacol. 287(2):149-160.

Lytle KA, Depner CM, Wong CP, Jump DB.  2015.  Docosahexaenoic acid attenuates Western diet-induced hepatic fibrosis in Ldlr-/- mice by targeting the TGFβ-Smad3 pathway.. J Lipid Res. 56(10):1936-46.

Perera T, Young MR, Zhang Z, Murphy G, Colburn NH, Lanza E, Hartman TJ, Cross AJ, Bobe G.  2015.  Identification and monitoring of metabolite markers of dry bean consumption in parallel human and mouse studies.. Mol Nutr Food Res. 59(4):795-806.

Pride H, Yu Z, Sunchu B, Mochnick J, Coles A, Zhang Y, Buffenstein R, Hornsby PJ, Austad SN, Perez VI.  2015.  Long-lived species have improved proteostasis compared to phylogenetically-related shorter-lived species.. Biochem Biophys Res Commun. 457(4):669-75.

Jump DB, Depner CM, Tripathy S, Lytle KA.  2015.  Potential for dietary ω-3 fatty acids to prevent nonalcoholic fatty liver disease and reduce the risk of primary liver cancer.. Adv Nutr. 6(6):694-702.

Yu Z, Wang R, Fok WC, Coles A, Salmon AB, Perez VI.  2015.  Rapamycin and dietary restriction induce metabolically distinctive changes in mouse liver.. J Gerontol A Biol Sci Med Sci. 70(4):410-20.

Wong CP, Rinaldi NA, Ho E.  2015.  Zinc deficiency enhanced inflammatory response by increasing immune cell activation and inducing IL6 promoter demethylation.. Mol Nutr Food Res. 59(5):991-9.

Okamoto R, Gery S, Gombart AF, Wang X, Castellani LW, Akagi T, Chen S, Arditi M, Ho Q, Lusis AJ et al..  2014.  Deficiency of CCAAT/enhancer binding protein-epsilon reduces atherosclerotic lesions in LDLR-/- mice.. PLoS One. 9(1):e85341.

Tripathy S, Lytle KA, Stevens RD, Bain JR, Newgard CB, Greenberg AS, Huang L-S, Jump DB.  2014.  Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice.. J Lipid Res. 55(7):1448-64.

Henderson MC, Siddens LK, Krueger SK, J Stevens F, Kedzie K, Fang WK, Heidelbaugh T, Nguyen P, Chow K, Garst M et al..  2014.  Flavin-containing monooxygenase S-oxygenation of a series of thioureas and thiones.. Toxicol Appl Pharmacol. 278(2):91-9.

Fok WC, Chen Y, Bokov A, Zhang Y, Salmon AB, Diaz V, Javors M, Wood WH, Zhang Y, Becker KG et al..  2014.  Mice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptome.. PLoS One. 9(1):e83988.

Zamzow DR, Elias V, Legette LCL, Choi J, J Stevens F, Magnusson KR.  2014.  Xanthohumol improved cognitive flexibility in young mice.. Behav Brain Res. 275:1-10.

Iwaniec UT, Turner RT, Smith BJ, Stoecker BJ, Rust A, Zhang B, Vasu VT, Gohil K, Cross CE, Traber MG.  2013.  Evaluation of long-term vitamin E insufficiency or excess on bone mass, density, and microarchitecture in rodents.. Free Radic Biol Med. 65:1209-1214.

Depner CM, Traber MG, Bobe G, Kensicki E, Bohren KM, Milne G, Jump DB.  2013.  A metabolomic analysis of omega-3 fatty acid-mediated attenuation of western diet-induced nonalcoholic steatohepatitis in LDLR-/- mice.. PLoS One. 8(12):e83756.