Found 333 results
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Superoxides
Robinson KM, Janes MS, Pehar M, Monette JS, Ross MF, Hagen TM, Murphy MP, Beckman JS.  2006.  Selective fluorescent imaging of superoxide in vivo using ethidium-based probes.. Proc Natl Acad Sci U S A. 103(41):15038-43.
Beckman JS.  2002.  Protein tyrosine nitration and peroxynitrite.. FASEB J. 16(9):1144.
Robinson KM, Janes MS, Beckman JS.  2008.  The selective detection of mitochondrial superoxide by live cell imaging.. Nat Protoc. 3(6):941-7.
Superoxide Dismutase-1
Kovacs M, Trias E, Varela V, Ibarburu S, Beckman JS, Moura IC, Hermine O, King PH, Si Y, Kwon Y et al..  2019.  CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS.. Int J Mol Sci. 20(16)
Liddell JR, Hilton JBW, Kysenius K, Billings JL, Nikseresht S, McInnes LE, Hare DJ, Paul B, Mercer SW, Belaidi AA et al..  2024.  Microglial ferroptotic stress causes non-cell autonomous neuronal death.. Mol Neurodegener. 19(1):14.
Hilton JBW, Kysenius K, Liddell JR, Mercer SW, Paul B, Beckman JS, McLean CA, White AR, Donnelly PS, Bush AI et al..  2024.  Evidence for disrupted copper availability in human spinal cord supports Cu(atsm) as a treatment option for sporadic cases of ALS.. Sci Rep. 14(1):5929.
Superoxide Dismutase
Trumbull KA, Beckman JS.  2009.  A role for copper in the toxicity of zinc-deficient superoxide dismutase to motor neurons in amyotrophic lateral sclerosis.. Antioxid Redox Signal. 11(7):1627-39.
Niedzwiecki A, Reveillaud I, Fleming JE.  1992.  Changes in superoxide dismutase and catalase in aging heat-shocked Drosophila.. Free Radic Res Commun. 17(6):355-67.
Wei H, Frei B, Beckman JS, Zhang W-J.  2011.  Copper chelation by tetrathiomolybdate inhibits lipopolysaccharide-induced inflammatory responses in vivo.. Am J Physiol Heart Circ Physiol. 301(3):H712-20.
Robinson KM, Janes MS, Beckman JS.  2008.  The selective detection of mitochondrial superoxide by live cell imaging.. Nat Protoc. 3(6):941-7.
Hilton JBW, Kysenius K, Liddell JR, Mercer SW, Paul B, Beckman JS, McLean CA, White AR, Donnelly PS, Bush AI et al..  2024.  Evidence for disrupted copper availability in human spinal cord supports Cu(atsm) as a treatment option for sporadic cases of ALS.. Sci Rep. 14(1):5929.
Trumbull KA, McAllister D, Gandelman MM, Fung WY, Lew T, Brennan L, Lopez N, Morré J, Kalyanaraman B, Beckman JS.  2012.  Diapocynin and apocynin administration fails to significantly extend survival in G93A SOD1 ALS mice.. Neurobiol Dis. 45(1):137-44.
Beckman JS, Estévez AG, Crow JP, Barbeito L.  2001.  Superoxide dismutase and the death of motoneurons in ALS.. Trends Neurosci. 24(11 Suppl):S15-20.
Hilton JB, Mercer SW, Lim NKH, Faux NG, Buncic G, Beckman JS, Roberts BR, Donnelly PS, White AR, Crouch PJ.  2017.  Cu(atsm) improves the neurological phenotype and survival of SOD1 mice and selectively increases enzymatically active SOD1 in the spinal cord.. Sci Rep. 7:42292.
Leinweber B, Barofsky E, Barofsky DF, Ermilov V, Nylin K, Beckman JS.  2004.  Aggregation of ALS mutant superoxide dismutase expressed in Escherichia coli.. Free Radic Biol Med. 36(7):911-8.
Beckman JS, Esétvez AG, Barbeito L, Crow JP.  2002.  CCS knockout mice establish an alternative source of copper for SOD in ALS.. Free Radic Biol Med. 33(10):1433-5.
Ermilova IP, Ermilov VB, Levy M, Ho E, Pereira C, Beckman JS.  2005.  Protection by dietary zinc in ALS mutant G93A SOD transgenic mice.. Neurosci Lett. 379(1):42-6.
Song Y, Chung CS, Bruno RS, Traber MG, Brown KH, King JC, Ho E.  2009.  Dietary zinc restriction and repletion affects DNA integrity in healthy men.. Am J Clin Nutr. 90(2):321-8.
Trias E, Ibarburu S, Barreto-Núñez R, Babdor J, Maciel TT, Guillo M, Gros L, Dubreuil P, Díaz-Amarilla P, Cassina P et al..  2016.  Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis.. J Neuroinflammation. 13(1):177.
Reveillaud I, Phillips J, Duyf B, Hilliker A, Kongpachith A, Fleming JE.  1994.  Phenotypic rescue by a bovine transgene in a Cu/Zn superoxide dismutase-null mutant of Drosophila melanogaster.. Mol Cell Biol. 14(2):1302-7.
Beckman JS.  2009.  Understanding peroxynitrite biochemistry and its potential for treating human diseases.. Arch Biochem Biophys. 484(2):114-6.
Williams JR, Trias E, Beilby PR, Lopez NI, Labut EM, C Bradford S, Roberts BR, McAllum EJ, Crouch PJ, Rhoads TW et al..  2016.  Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD(G93A) mice co-expressing the Copper-Chaperone-for-SOD.. Neurobiol Dis. 89:1-9.
Fleming JE, Reveillaud I, Niedzwiecki A.  1992.  Role of oxidative stress in Drosophila aging.. Mutat Res. 275(3-6):267-79.
Reveillaud I, Kongpachith A, Park R, Fleming JE.  1992.  Stress resistance of Drosophila transgenic for bovine CuZn superoxide dismutase.. Free Radic Res Commun. 17(1):73-85.
Sulindac
Orner GA, Dashwood W-M, Blum CA, G Díaz D, Li Q, Al-Fageeh M, Tebbutt N, Heath JK, Ernst M, Dashwood RH.  2002.  Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).. Mutat Res. 506-507:121-7.

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