Found 289 results
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Superoxide Dismutase
Trumbull KA, Beckman JS.  2009.  A role for copper in the toxicity of zinc-deficient superoxide dismutase to motor neurons in amyotrophic lateral sclerosis.. Antioxid Redox Signal. 11(7):1627-39.
Beckman JS.  2009.  Understanding peroxynitrite biochemistry and its potential for treating human diseases.. Arch Biochem Biophys. 484(2):114-6.
Williams JR, Trias E, Beilby PR, Lopez NI, Labut EM, C Bradford S, Roberts BR, McAllum EJ, Crouch PJ, Rhoads TW et al..  2016.  Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD(G93A) mice co-expressing the Copper-Chaperone-for-SOD.. Neurobiol Dis. 89:1-9.
Trias E, Ibarburu S, Barreto-Núñez R, Babdor J, Maciel TT, Guillo M, Gros L, Dubreuil P, Díaz-Amarilla P, Cassina P et al..  2016.  Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis.. J Neuroinflammation. 13(1):177.
Ermilova IP, Ermilov VB, Levy M, Ho E, Pereira C, Beckman JS.  2005.  Protection by dietary zinc in ALS mutant G93A SOD transgenic mice.. Neurosci Lett. 379(1):42-6.
Beckman JS, Esétvez AG, Barbeito L, Crow JP.  2002.  CCS knockout mice establish an alternative source of copper for SOD in ALS.. Free Radic Biol Med. 33(10):1433-5.
Robinson KM, Janes MS, Beckman JS.  2008.  The selective detection of mitochondrial superoxide by live cell imaging.. Nat Protoc. 3(6):941-7.
Hilton JB, Mercer SW, Lim NKH, Faux NG, Buncic G, Beckman JS, Roberts BR, Donnelly PS, White AR, Crouch PJ.  2017.  Cu(atsm) improves the neurological phenotype and survival of SOD1 mice and selectively increases enzymatically active SOD1 in the spinal cord.. Sci Rep. 7:42292.
Trumbull KA, McAllister D, Gandelman MM, Fung WY, Lew T, Brennan L, Lopez N, Morré J, Kalyanaraman B, Beckman JS.  2012.  Diapocynin and apocynin administration fails to significantly extend survival in G93A SOD1 ALS mice.. Neurobiol Dis. 45(1):137-44.
Superoxide Dismutase-1
Kovacs M, Trias E, Varela V, Ibarburu S, Beckman JS, Moura IC, Hermine O, King PH, Si Y, Kwon Y et al..  2019.  CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS.. Int J Mol Sci. 20(16)
Superoxides
Robinson KM, Janes MS, Beckman JS.  2008.  The selective detection of mitochondrial superoxide by live cell imaging.. Nat Protoc. 3(6):941-7.
Robinson KM, Janes MS, Pehar M, Monette JS, Ross MF, Hagen TM, Murphy MP, Beckman JS.  2006.  Selective fluorescent imaging of superoxide in vivo using ethidium-based probes.. Proc Natl Acad Sci U S A. 103(41):15038-43.
Schwarzländer M, Wagner S, Ermakova YG, Belousov VV, Radi R, Beckman JS, Buettner GR, Demaurex N, Duchen MR, Forman HJ et al..  2014.  The 'mitoflash' probe cpYFP does not respond to superoxide.. Nature. 514(7523):E12-4.
Beckman JS.  2002.  Protein tyrosine nitration and peroxynitrite.. FASEB J. 16(9):1144.
Beckman JS.  2009.  Understanding peroxynitrite biochemistry and its potential for treating human diseases.. Arch Biochem Biophys. 484(2):114-6.
Survival Analysis
Hilton JB, Mercer SW, Lim NKH, Faux NG, Buncic G, Beckman JS, Roberts BR, Donnelly PS, White AR, Crouch PJ.  2017.  Cu(atsm) improves the neurological phenotype and survival of SOD1 mice and selectively increases enzymatically active SOD1 in the spinal cord.. Sci Rep. 7:42292.
Tandem Mass Spectrometry
Shaw JB, Malhan N, Vasil'ev YV, Lopez NI, Makarov A, Beckman JS, Voinov VG.  2018.  Sequencing Grade Tandem Mass Spectrometry for Top-Down Proteomics Using Hybrid Electron Capture Dissociation Methods in a Benchtop Orbitrap Mass Spectrometer.. Anal Chem. 90(18):10819-10827.
Mukherjee S, Kapp EA, Lothian A, Roberts AM, Vasil'ev YV, Boughton BA, Barnham KJ, W Kok M, Hutton CA, Masters CL et al..  2017.  Characterization and Identification of Dityrosine Cross-Linked Peptides Using Tandem Mass Spectrometry.. Anal Chem. 89(11):6136-6145.
Fort KL, Cramer CN, Voinov VG, Vasil'ev YV, Lopez NI, Beckman JS, Heck AJR.  2018.  Exploring ECD on a Benchtop Q Exactive Orbitrap Mass Spectrometer.. J Proteome Res. 17(2):926-933.
Thiazoles
Trias E, Ibarburu S, Barreto-Núñez R, Babdor J, Maciel TT, Guillo M, Gros L, Dubreuil P, Díaz-Amarilla P, Cassina P et al..  2016.  Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis.. J Neuroinflammation. 13(1):177.
Thiosemicarbazones
Hilton JB, Mercer SW, Lim NKH, Faux NG, Buncic G, Beckman JS, Roberts BR, Donnelly PS, White AR, Crouch PJ.  2017.  Cu(atsm) improves the neurological phenotype and survival of SOD1 mice and selectively increases enzymatically active SOD1 in the spinal cord.. Sci Rep. 7:42292.
Time Factors
Ermilova IP, Ermilov VB, Levy M, Ho E, Pereira C, Beckman JS.  2005.  Protection by dietary zinc in ALS mutant G93A SOD transgenic mice.. Neurosci Lett. 379(1):42-6.
Tissue Extracts
Hilton JB, Mercer SW, Lim NKH, Faux NG, Buncic G, Beckman JS, Roberts BR, Donnelly PS, White AR, Crouch PJ.  2017.  Cu(atsm) improves the neurological phenotype and survival of SOD1 mice and selectively increases enzymatically active SOD1 in the spinal cord.. Sci Rep. 7:42292.
Transcription Factor AP-1
Wei H, Frei B, Beckman JS, Zhang W-J.  2011.  Copper chelation by tetrathiomolybdate inhibits lipopolysaccharide-induced inflammatory responses in vivo.. Am J Physiol Heart Circ Physiol. 301(3):H712-20.
Treatment Outcome
Trumbull KA, McAllister D, Gandelman MM, Fung WY, Lew T, Brennan L, Lopez N, Morré J, Kalyanaraman B, Beckman JS.  2012.  Diapocynin and apocynin administration fails to significantly extend survival in G93A SOD1 ALS mice.. Neurobiol Dis. 45(1):137-44.

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