Found 388 results
Author [ Keyword(Asc)] Title Type Year
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Diet
Lim Y, Schock BC, Gohil K, Leonard SW, Packer L, Cross CE, Traber MG.  2004.  Gene-nutrient interactions exemplified by the alpha-tocopherol content of tissues from alpha-tocopherol transfer protein-null mice fed different dietary vitamin E concentrations.. Ann N Y Acad Sci. 1031:328-9.
Bella DL, Schock BC, Lim Y, Leonard SW, Berry C, Cross CE, Traber MG.  2006.  Regulation of the alpha-tocopherol transfer protein in mice: lack of response to dietary vitamin E or oxidative stress.. Lipids. 41(2):105-12.
Deuterium
Leonard SW, Terasawa Y, Farese RV, Traber MG.  2002.  Incorporation of deuterated RRR- or all-rac-alpha-tocopherol in plasma and tissues of alpha-tocopherol transfer protein--null mice.. Am J Clin Nutr. 75(3):555-60.
Traber MG, Leonard SW, Ebenuwa I, Violet P-C, Wang Y, Niyyati M, Padayatty S, Tu H, Courville A, Bernstein S et al..  2019.  Vitamin E absorption and kinetics in healthy women, as modulated by food and by fat, studied using 2 deuterium-labeled α-tocopherols in a 3-phase crossover design.. Am J Clin Nutr. 110(5):1148-1167.
Traber MG, Leonard SW, Bobe G, Fu X, Saltzman E, Grusak MA, Booth SL.  2015.  α-Tocopherol disappearance rates from plasma depend on lipid concentrations: studies using deuterium-labeled collard greens in younger and older adults.. Am J Clin Nutr. 101(4):752-9.
Leonard SW, Bruno RS, Ramakrishnan R, Bray T, Traber MG.  2004.  Cigarette smoking increases human vitamin E requirements as estimated by plasma deuterium-labeled CEHC.. Ann N Y Acad Sci. 1031:357-60.
Farley SM, Leonard SW, Stevens JF, Traber MG.  2014.  Deuterium-labeled phylloquinone fed to α-tocopherol-injected rats demonstrates sensitivity of low phylloquinone-containing tissues to menaquinone-4 depletion.. Mol Nutr Food Res. 58(8):1610-9.
Cytochrome P450 Family 4
Farley SM, Leonard SW, Taylor AW, Birringer M, Edson KZ, Rettie AE, Traber MG.  2013.  ω-Hydroxylation of phylloquinone by CYP4F2 is not increased by α-tocopherol.. Mol Nutr Food Res. 57(10):1785-93.
Cytochrome P-450 Enzyme System
Farley SM, Leonard SW, Taylor AW, Birringer M, Edson KZ, Rettie AE, Traber MG.  2013.  ω-Hydroxylation of phylloquinone by CYP4F2 is not increased by α-tocopherol.. Mol Nutr Food Res. 57(10):1785-93.
Mustacich DJ, Vo AT, Elias VD, Payne K, Sullivan L, Leonard SW, Traber MG.  2007.  Regulatory mechanisms to control tissue alpha-tocopherol.. Free Radic Biol Med. 43(4):610-8.
Traber MG, Mustacich DJ, Sullivan LC, Leonard SW, Ahern-Rindell A, Kerkvliet N.  2010.  Vitamin E status and metabolism in adult and aged aryl hydrocarbon receptor null mice.. J Nutr Biochem. 21(12):1193-9.
Mustacich DJ, Leonard SW, Devereaux MW, Sokol RJ, Traber MG.  2006.  Alpha-tocopherol regulation of hepatic cytochrome P450s and ABC transporters in rats.. Free Radic Biol Med. 41(7):1069-78.
Traber MG, Labut EM, Leonard SW, Lebold KM.  2011.  α-Tocopherol injections in rats up-regulate hepatic ABC transporters, but not cytochrome P450 enzymes.. Free Radic Biol Med. 51(11):2031-40.
Cytochrome P-450 CYP3A
Traber MG, Siddens LK, Leonard SW, Schock B, Gohil K, Krueger SK, Cross CE, Williams DE.  2005.  Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets.. Free Radic Biol Med. 38(6):773-85.
Cytochrome P-450 CYP2B1
Mustacich DJ, Leonard SW, Patel NK, Traber MG.  2010.  Alpha-tocopherol beta-oxidation localized to rat liver mitochondria.. Free Radic Biol Med. 48(1):73-81.
Cystic Fibrosis
Traber MG, Leonard SW, Vasu VT, Morrissey BM, Lei HJohn, Atkinson J, Cross CE.  2022.  α-Tocopherol Pharmacokinetics in Adults with Cystic Fibrosis: Benefits of Supplemental Vitamin C Administration.. Nutrients. 14(18)
Cross-Over Studies
Bruno RS, Leonard SW, Atkinson J, Montine TJ, Ramakrishnan R, Bray TM, Traber MG.  2006.  Faster plasma vitamin E disappearance in smokers is normalized by vitamin C supplementation.. Free Radic Biol Med. 40(4):689-97.
Traber MG, Leonard SW, Ebenuwa I, Violet P-C, Wang Y, Niyyati M, Padayatty S, Tu H, Courville A, Bernstein S et al..  2019.  Vitamin E absorption and kinetics in healthy women, as modulated by food and by fat, studied using 2 deuterium-labeled α-tocopherols in a 3-phase crossover design.. Am J Clin Nutr. 110(5):1148-1167.
Bobe G, Cobb TJ, Leonard SW, Aponso S, Bahro CB, Koley D, Mah E, Bruno RS, Traber MG.  2017.  Increased static and decreased capacity oxidation-reduction potentials in plasma are predictive of metabolic syndrome.. Redox Biol. 12:121-128.
Traber MG, Mah E, Leonard SW, Bobe G, Bruno RS.  2017.  Metabolic syndrome increases dietary α-tocopherol requirements as assessed using urinary and plasma vitamin E catabolites: a double-blind, crossover clinical trial.. Am J Clin Nutr. 105(3):571-579.
Creatinine
Traber MG, Mah E, Leonard SW, Bobe G, Bruno RS.  2017.  Metabolic syndrome increases dietary α-tocopherol requirements as assessed using urinary and plasma vitamin E catabolites: a double-blind, crossover clinical trial.. Am J Clin Nutr. 105(3):571-579.
Chromatography, Liquid
Leonard SW, Gumpricht E, Devereaux MW, Sokol RJ, Traber MG.  2005.  Quantitation of rat liver vitamin E metabolites by LC-MS during high-dose vitamin E administration.. J Lipid Res. 46(5):1068-75.
Traber MG, Leonard SW, Bobe G, Fu X, Saltzman E, Grusak MA, Booth SL.  2015.  α-Tocopherol disappearance rates from plasma depend on lipid concentrations: studies using deuterium-labeled collard greens in younger and older adults.. Am J Clin Nutr. 101(4):752-9.
Chromatography, High Pressure Liquid
Leonard SW, Traber MG.  2006.  Measurement of the vitamin E metabolites, carboxyethyl hydroxychromans (CEHCs), in biological samples.. Curr Protoc Toxicol. Chapter 7:Unit7.8.
Farley SM, Leonard SW, Taylor AW, Birringer M, Edson KZ, Rettie AE, Traber MG.  2013.  ω-Hydroxylation of phylloquinone by CYP4F2 is not increased by α-tocopherol.. Mol Nutr Food Res. 57(10):1785-93.

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