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Found 582 results
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Williams, David E
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Indoles
Beaver LM
,
Yu T-W
,
Sokolowski EI
,
Williams DE
,
Dashwood RH
,
Ho E
. 2012.
3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.
.
Toxicol Appl Pharmacol. 263(3):345-51.
Palomera-Sanchez Z
,
Watson GW
,
Wong CP
,
Beaver LM
,
Williams DE
,
Dashwood RH
,
Ho E
. 2017.
The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.
.
J Nutr Biochem. 47:113-119.
Immunohistochemistry
Wang R
,
Löhr CV
,
Fischer K
,
W Dashwood M
,
Greenwood JA
,
Ho E
,
Williams DE
,
Ashktorab H
,
Dashwood MR
,
Dashwood RH
. 2013.
Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.
.
Int J Cancer. 132(5):1004-12.
Imidazoles
Wang R
,
W Dashwood M
,
Löhr CV
,
Fischer KA
,
Nakagama H
,
Williams DE
,
Dashwood RH
. 2008.
beta-catenin is strongly elevated in rat colonic epithelium following short-term intermittent treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and a high-fat diet.
.
Cancer Sci. 99(9):1754-9.
Chen Y-S
,
Wang R
,
Dashwood W-M
,
Löhr CV
,
Williams DE
,
Ho E
,
Mertens-Talcott S
,
Dashwood RH
. 2017.
A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat.
.
Arch Toxicol. 91(10):3415-3425.
Parasramka MA
,
W Dashwood M
,
Wang R
,
Abdelli A
,
Bailey GS
,
Williams DE
,
Ho E
,
Dashwood RH
. 2012.
MicroRNA profiling of carcinogen-induced rat colon tumors and the influence of dietary spinach.
.
Mol Nutr Food Res. 56(8):1259-69.
Wang R
,
W Dashwood M
,
Löhr CV
,
Fischer KA
,
Pereira CB
,
Louderback M
,
Nakagama H
,
Bailey GS
,
Williams DE
,
Dashwood RH
. 2008.
Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat.
.
Carcinogenesis. 29(4):834-9.
Wang R
,
Chen Y-S
,
Dashwood W-M
,
Li Q
,
Löhr CV
,
Fischer K
,
Ho E
,
Williams DE
,
Dashwood RH
. 2017.
Divergent roles of p120-catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen-induced rat skin tumors.
.
Mol Carcinog. 56(7):1733-1742.
Hydroxamic Acids
Rajendran P
,
Williams DE
,
Ho E
,
Dashwood RH
. 2011.
Metabolism as a key to histone deacetylase inhibition.
.
Crit Rev Biochem Mol Biol. 46(3):181-99.
Hydrogen-Ion Concentration
Krueger SK
,
Henderson MC
,
Siddens LK
,
VanDyke JE
,
Benninghoff AD
,
P Karplus A
,
Furnes B
,
Schlenk D
,
Williams DE
. 2009.
Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K.
.
Drug Metab Dispos. 37(8):1785-91.
Krueger SK
,
Martin SR
,
Yueh M-F
,
Pereira CB
,
Williams DE
. 2002.
Identification of active flavin-containing monooxygenase isoform 2 in human lung and characterization of expressed protein.
.
Drug Metab Dispos. 30(1):34-41.
Hydrogen Peroxide
Siddens LK
,
Krueger SK
,
Henderson MC
,
Williams DE
. 2014.
Mammalian flavin-containing monooxygenase (FMO) as a source of hydrogen peroxide.
.
Biochem Pharmacol. 89(1):141-7.
Humans
Krueger SK
,
Henderson MC
,
Siddens LK
,
VanDyke JE
,
Benninghoff AD
,
P Karplus A
,
Furnes B
,
Schlenk D
,
Williams DE
. 2009.
Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K.
.
Drug Metab Dispos. 37(8):1785-91.
Rajendran P
,
Kidane AI
,
Yu T-W
,
Dashwood W-M
,
Bisson WH
,
Löhr CV
,
Ho E
,
Williams DE
,
Dashwood RH
. 2013.
HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates.
.
Epigenetics. 8(6):612-23.
Madeen EP
,
Löhr CV
,
You H
,
Siddens LK
,
Krueger SK
,
Dashwood RH
,
Gonzalez FJ
,
Baird WM
,
Ho E
,
Bramer L
et al.
. 2017.
Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.
.
Mol Carcinog. 56(1):163-171.
Wang R
,
Chen Y-S
,
Dashwood W-M
,
Li Q
,
Löhr CV
,
Fischer K
,
Ho E
,
Williams DE
,
Dashwood RH
. 2017.
Divergent roles of p120-catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen-induced rat skin tumors.
.
Mol Carcinog. 56(7):1733-1742.
Watson GW
,
Wickramasekara S
,
Fang Y
,
Maier CS
,
Williams DE
,
Dashwood RH
,
Perez VI
,
Ho E
. 2016.
HDAC6 activity is not required for basal autophagic flux in metastatic prostate cancer cells.
.
Exp Biol Med (Maywood). 241(11):1177-85.
Wang R
,
Löhr CV
,
Fischer K
,
W Dashwood M
,
Greenwood JA
,
Ho E
,
Williams DE
,
Ashktorab H
,
Dashwood MR
,
Dashwood RH
. 2013.
Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.
.
Int J Cancer. 132(5):1004-12.
Leibelt DA
,
Hedstrom OR
,
Fischer KA
,
Pereira CB
,
Williams DE
. 2003.
Evaluation of chronic dietary exposure to indole-3-carbinol and absorption-enhanced 3,3'-diindolylmethane in sprague-dawley rats.
.
Toxicol Sci. 74(1):10-21.
Beaver LM
,
Yu T-W
,
Sokolowski EI
,
Williams DE
,
Dashwood RH
,
Ho E
. 2012.
3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.
.
Toxicol Appl Pharmacol. 263(3):345-51.
Henderson MC
,
Siddens LK
,
Krueger SK
,
J Stevens F
,
Kedzie K
,
Fang WK
,
Heidelbaugh T
,
Nguyen P
,
Chow K
,
Garst M
et al.
. 2014.
Flavin-containing monooxygenase S-oxygenation of a series of thioureas and thiones.
.
Toxicol Appl Pharmacol. 278(2):91-9.
Siddens LK
,
Krueger SK
,
Henderson MC
,
Williams DE
. 2014.
Mammalian flavin-containing monooxygenase (FMO) as a source of hydrogen peroxide.
.
Biochem Pharmacol. 89(1):141-7.
Chen Y-S
,
Wang R
,
Dashwood W-M
,
Löhr CV
,
Williams DE
,
Ho E
,
Mertens-Talcott S
,
Dashwood RH
. 2017.
A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat.
.
Arch Toxicol. 91(10):3415-3425.
Palomera-Sanchez Z
,
Watson GW
,
Wong CP
,
Beaver LM
,
Williams DE
,
Dashwood RH
,
Ho E
. 2017.
The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.
.
J Nutr Biochem. 47:113-119.
Rajendran P
,
Williams DE
,
Ho E
,
Dashwood RH
. 2011.
Metabolism as a key to histone deacetylase inhibition.
.
Crit Rev Biochem Mol Biol. 46(3):181-99.
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