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Found 582 results
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Williams, David E
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Indoles
Tilton SC
,
Givan SA
,
Pereira CB
,
Bailey GS
,
Williams DE
. 2006.
Toxicogenomic profiling of the hepatic tumor promoters indole-3-carbinol, 17beta-estradiol and beta-naphthoflavone in rainbow trout.
.
Toxicol Sci. 90(1):61-72.
Wong CP
,
Hsu A
,
Buchanan A
,
Palomera-Sanchez Z
,
Beaver LM
,
E Houseman A
,
Williams DE
,
Dashwood RH
,
Ho E
. 2014.
Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells.
.
PLoS One. 9(1):e86787.
Immunohistochemistry
Wang R
,
Löhr CV
,
Fischer K
,
W Dashwood M
,
Greenwood JA
,
Ho E
,
Williams DE
,
Ashktorab H
,
Dashwood MR
,
Dashwood RH
. 2013.
Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.
.
Int J Cancer. 132(5):1004-12.
Imidazoles
Wang R
,
W Dashwood M
,
Löhr CV
,
Fischer KA
,
Pereira CB
,
Louderback M
,
Nakagama H
,
Bailey GS
,
Williams DE
,
Dashwood RH
. 2008.
Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat.
.
Carcinogenesis. 29(4):834-9.
Wang R
,
Chen Y-S
,
Dashwood W-M
,
Li Q
,
Löhr CV
,
Fischer K
,
Ho E
,
Williams DE
,
Dashwood RH
. 2017.
Divergent roles of p120-catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen-induced rat skin tumors.
.
Mol Carcinog. 56(7):1733-1742.
Wang R
,
W Dashwood M
,
Löhr CV
,
Fischer KA
,
Nakagama H
,
Williams DE
,
Dashwood RH
. 2008.
beta-catenin is strongly elevated in rat colonic epithelium following short-term intermittent treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and a high-fat diet.
.
Cancer Sci. 99(9):1754-9.
Chen Y-S
,
Wang R
,
Dashwood W-M
,
Löhr CV
,
Williams DE
,
Ho E
,
Mertens-Talcott S
,
Dashwood RH
. 2017.
A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat.
.
Arch Toxicol. 91(10):3415-3425.
Parasramka MA
,
W Dashwood M
,
Wang R
,
Abdelli A
,
Bailey GS
,
Williams DE
,
Ho E
,
Dashwood RH
. 2012.
MicroRNA profiling of carcinogen-induced rat colon tumors and the influence of dietary spinach.
.
Mol Nutr Food Res. 56(8):1259-69.
Hydroxamic Acids
Rajendran P
,
Williams DE
,
Ho E
,
Dashwood RH
. 2011.
Metabolism as a key to histone deacetylase inhibition.
.
Crit Rev Biochem Mol Biol. 46(3):181-99.
Hydrogen-Ion Concentration
Krueger SK
,
Martin SR
,
Yueh M-F
,
Pereira CB
,
Williams DE
. 2002.
Identification of active flavin-containing monooxygenase isoform 2 in human lung and characterization of expressed protein.
.
Drug Metab Dispos. 30(1):34-41.
Krueger SK
,
Henderson MC
,
Siddens LK
,
VanDyke JE
,
Benninghoff AD
,
P Karplus A
,
Furnes B
,
Schlenk D
,
Williams DE
. 2009.
Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K.
.
Drug Metab Dispos. 37(8):1785-91.
Hydrogen Peroxide
Siddens LK
,
Krueger SK
,
Henderson MC
,
Williams DE
. 2014.
Mammalian flavin-containing monooxygenase (FMO) as a source of hydrogen peroxide.
.
Biochem Pharmacol. 89(1):141-7.
Humans
Williams DE
. 2018.
Association Is Not Causation.
.
Toxicol Sci. 164(1):3.
Wong CP
,
Hsu A
,
Buchanan A
,
Palomera-Sanchez Z
,
Beaver LM
,
E Houseman A
,
Williams DE
,
Dashwood RH
,
Ho E
. 2014.
Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells.
.
PLoS One. 9(1):e86787.
Watson GW
,
Wickramasekara S
,
Fang Y
,
Palomera-Sanchez Z
,
Maier CS
,
Williams DE
,
Dashwood RH
,
Perez VI
,
Ho E
. 2015.
Analysis of autophagic flux in response to sulforaphane in metastatic prostate cancer cells.
.
Mol Nutr Food Res. 59(10):1954-61.
Krueger SK
,
Williams DE
,
Yueh M-F
,
Martin SR
,
Hines RN
,
Raucy JL
,
Dolphin CT
,
Shephard EA
,
Phillips IR
. 2002.
Genetic polymorphisms of flavin-containing monooxygenase (FMO).
.
Drug Metab Rev. 34(3):523-32.
Hummel JM
,
Madeen EP
,
Siddens LK
,
Uesugi SL
,
McQuistan T
,
Anderson KA
,
Turteltaub KW
,
Ognibene TJ
,
Bench G
,
Krueger SK
et al.
. 2018.
Pharmacokinetics of [C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction.
.
Food Chem Toxicol. 115:136-147.
Krueger SK
,
Martin SR
,
Yueh M-F
,
Pereira CB
,
Williams DE
. 2002.
Identification of active flavin-containing monooxygenase isoform 2 in human lung and characterization of expressed protein.
.
Drug Metab Dispos. 30(1):34-41.
Chimploy K
,
G Díaz D
,
Li Q
,
Carter O
,
Dashwood W-M
,
Mathews CK
,
Williams DE
,
Bailey GS
,
Dashwood RH
. 2009.
E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin.
.
Int J Cancer. 125(9):2086-94.
Henderson MC
,
Krueger SK
,
Stevens JF
,
Williams DE
. 2004.
Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione.
.
Chem Res Toxicol. 17(5):633-40.
Parasramka MA
,
Ho E
,
Williams DE
,
Dashwood RH
. 2012.
MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals.
.
Mol Carcinog. 51(3):213-30.
Ho E
,
Beaver LM
,
Williams DE
,
Dashwood RH
. 2011.
Dietary factors and epigenetic regulation for prostate cancer prevention.
.
Adv Nutr. 2(6):497-510.
Wang R
,
Kang Y
,
Löhr CV
,
Fischer KA
,
C Bradford S
,
Johnson G
,
Dashwood WMohaiza
,
Williams DE
,
Ho E
,
Dashwood RH
. 2016.
Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer.
.
Cancer Lett. 381(2):341-8.
Higdon JV
,
Delage B
,
Williams DE
,
Dashwood RH
. 2007.
Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis.
.
Pharmacol Res. 55(3):224-36.
Traber MG
,
Siddens LK
,
Leonard SW
,
Schock B
,
Gohil K
,
Krueger SK
,
Cross CE
,
Williams DE
. 2005.
Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets.
.
Free Radic Biol Med. 38(6):773-85.
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