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Ho, Emily
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Histone Deacetylases
Beaver LM
,
Yu T-W
,
Sokolowski EI
,
Williams DE
,
Dashwood RH
,
Ho E
. 2012.
3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.
.
Toxicol Appl Pharmacol. 263(3):345-51.
Watson GW
,
Wickramasekara S
,
Fang Y
,
Maier CS
,
Williams DE
,
Dashwood RH
,
Perez VI
,
Ho E
. 2016.
HDAC6 activity is not required for basal autophagic flux in metastatic prostate cancer cells.
.
Exp Biol Med (Maywood). 241(11):1177-85.
Rajendran P
,
Kidane AI
,
Yu T-W
,
Dashwood W-M
,
Bisson WH
,
Löhr CV
,
Ho E
,
Williams DE
,
Dashwood RH
. 2013.
HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates.
.
Epigenetics. 8(6):612-23.
Histones
Abbas A
,
J Hall A
,
Patterson WL
,
Ho E
,
Hsu A
,
Al-Mulla F
,
Georgel PT
. 2016.
Sulforaphane modulates telomerase activity via epigenetic regulation in prostate cancer cell lines.
.
Biochem Cell Biol. 94(1):71-81.
Myzak MC
,
W Dashwood M
,
Orner GA
,
Ho E
,
Dashwood RH
. 2006.
Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice.
.
FASEB J. 20(3):506-8.
Ho E
,
Beaver LM
,
Williams DE
,
Dashwood RH
. 2011.
Dietary factors and epigenetic regulation for prostate cancer prevention.
.
Adv Nutr. 2(6):497-510.
Homeostasis
Beaver LM
,
Nkrumah-Elie YM
,
Truong L
,
Barton CL
,
Knecht AL
,
Gonnerman GD
,
Wong CP
,
Tanguay RL
,
Ho E
. 2017.
Adverse effects of parental zinc deficiency on metal homeostasis and embryonic development in a zebrafish model.
.
J Nutr Biochem. 43:78-87.
HT29 Cells
Wang R
,
Löhr CV
,
Fischer K
,
W Dashwood M
,
Greenwood JA
,
Ho E
,
Williams DE
,
Ashktorab H
,
Dashwood MR
,
Dashwood RH
. 2013.
Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.
.
Int J Cancer. 132(5):1004-12.
Humans
Johnson GS
,
Li J
,
Beaver LM
,
W Dashwood M
,
Sun D
,
Rajendran P
,
Williams DE
,
Ho E
,
Dashwood RH
. 2017.
A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a coactivator of NQO1 in sulforaphane-treated colon cancer cells.
.
Mol Nutr Food Res. 61(4)
Wang R
,
Chen Y-S
,
Dashwood W-M
,
Li Q
,
Löhr CV
,
Fischer K
,
Ho E
,
Williams DE
,
Dashwood RH
. 2017.
Divergent roles of p120-catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen-induced rat skin tumors.
.
Mol Carcinog. 56(7):1733-1742.
Myzak MC
,
Ho E
,
Dashwood RH
. 2006.
Dietary agents as histone deacetylase inhibitors.
.
Mol Carcinog. 45(6):443-6.
Myzak MC
,
Hardin K
,
Wang R
,
Dashwood RH
,
Ho E
. 2006.
Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells.
.
Carcinogenesis. 27(4):811-9.
Ho E
. 2004.
Zinc deficiency, DNA damage and cancer risk.
.
J Nutr Biochem. 15(10):572-8.
Watson GW
,
Wickramasekara S
,
Fang Y
,
Maier CS
,
Williams DE
,
Dashwood RH
,
Perez VI
,
Ho E
. 2016.
HDAC6 activity is not required for basal autophagic flux in metastatic prostate cancer cells.
.
Exp Biol Med (Maywood). 241(11):1177-85.
Watson GW
,
Wickramasekara S
,
Fang Y
,
Palomera-Sanchez Z
,
Maier CS
,
Williams DE
,
Dashwood RH
,
Perez VI
,
Ho E
. 2015.
Analysis of autophagic flux in response to sulforaphane in metastatic prostate cancer cells.
.
Mol Nutr Food Res. 59(10):1954-61.
Huang L
,
Drake VJ
,
Ho E
. 2015.
Zinc.
.
Adv Nutr. 6(2):224-6.
Ho E
,
Beaver LM
,
Williams DE
,
Dashwood RH
. 2011.
Dietary factors and epigenetic regulation for prostate cancer prevention.
.
Adv Nutr. 2(6):497-510.
Madeen EP
,
Löhr CV
,
You H
,
Siddens LK
,
Krueger SK
,
Dashwood RH
,
Gonzalez FJ
,
Baird WM
,
Ho E
,
Bramer L
et al.
. 2017.
Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.
.
Mol Carcinog. 56(1):163-171.
Parasramka MA
,
Ho E
,
Williams DE
,
Dashwood RH
. 2012.
MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals.
.
Mol Carcinog. 51(3):213-30.
Atwell LL
,
Zhang Z
,
Mori M
,
Farris P
,
Vetto JT
,
Naik AM
,
Oh KY
,
Thuillier P
,
Ho E
,
Shannon J
. 2015.
Sulforaphane Bioavailability and Chemopreventive Activity in Women Scheduled for Breast Biopsy.
.
Cancer Prev Res (Phila). 8(12):1184-1191.
Rajendran P
,
Williams DE
,
Ho E
,
Dashwood RH
. 2011.
Metabolism as a key to histone deacetylase inhibition.
.
Crit Rev Biochem Mol Biol. 46(3):181-99.
Wang R
,
Yu Z
,
Sunchu B
,
Shoaf J
,
Dang I
,
Zhao S
,
Caples K
,
Bradley L
,
Beaver LM
,
Ho E
et al.
. 2017.
Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2-independent mechanism.
.
Aging Cell. 16(3):564-574.
Song Y
,
Chung CS
,
Bruno RS
,
Traber MG
,
Brown KH
,
King JC
,
Ho E
. 2009.
Dietary zinc restriction and repletion affects DNA integrity in healthy men.
.
Am J Clin Nutr. 90(2):321-8.
Nian H
,
Delage B
,
Ho E
,
Dashwood RH
. 2009.
Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds.
.
Environ Mol Mutagen. 50(3):213-21.
Rajendran P
,
Kidane AI
,
Yu T-W
,
Dashwood W-M
,
Bisson WH
,
Löhr CV
,
Ho E
,
Williams DE
,
Dashwood RH
. 2013.
HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates.
.
Epigenetics. 8(6):612-23.
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