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Amines
Chen Y-S
,
Wang R
,
Dashwood W-M
,
Löhr CV
,
Williams DE
,
Ho E
,
Mertens-Talcott S
,
Dashwood RH
. 2017.
A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat.
.
Arch Toxicol. 91(10):3415-3425.
Amino Acid Sequence
Voinov VG
,
Hoffman PD
,
Bennett SE
,
Beckman JS
,
Barofsky DF
. 2015.
Electron Capture Dissociation of Sodium-Adducted Peptides on a Modified Quadrupole/Time-of-Flight Mass Spectrometer.
.
J Am Soc Mass Spectrom. 26(12):2096-104.
Li Q
,
Dixon BM
,
Al-Fageeh M
,
Blum CA
,
Dashwood RH
. 2002.
Sequencing of the rat beta-catenin gene (Ctnnb1) and mutational analysis of liver tumors induced by 2-amino-3-methylimidazo[4,5-f]quinoline.
.
Gene. 283(1-2):255-62.
Moreau R
,
Nguyen BT
,
Doneanu CE
,
Hagen TM
. 2005.
Reversal by aminoguanidine of the age-related increase in glycoxidation and lipoxidation in the cardiovascular system of Fischer 344 rats.
.
Biochem Pharmacol. 69(1):29-40.
Kubglomsong S
,
Theerakulkait C
,
Reed RL
,
Yang L
,
Maier CS
,
Stevens JF
. 2018.
Isolation and Identification of Tyrosinase-Inhibitory and Copper-Chelating Peptides from Hydrolyzed Rice-Bran-Derived Albumin.
.
J Agric Food Chem. 66(31):8346-8354.
Fort KL
,
Cramer CN
,
Voinov VG
,
Vasil'ev YV
,
Lopez NI
,
Beckman JS
,
Heck AJR
. 2018.
Exploring ECD on a Benchtop Q Exactive Orbitrap Mass Spectrometer.
.
J Proteome Res. 17(2):926-933.
Moreau R
,
Heath S-HD
,
Doneanu CE
,
Harris RA
,
Hagen TM
. 2004.
Age-related compensatory activation of pyruvate dehydrogenase complex in rat heart.
.
Biochem Biophys Res Commun. 325(1):48-58.
Boulikas T
. 1993.
Poly(ADP-ribosyl)ation, DNA strand breaks, chromatin and cancer.
.
Toxicol Lett. 67(1-3):129-50.
Moreau R
,
Heath S-HD
,
Doneanu CE
,
J Lindsay G
,
Hagen TM
. 2003.
Age-related increase in 4-hydroxynonenal adduction to rat heart alpha-ketoglutarate dehydrogenase does not cause loss of its catalytic activity.
.
Antioxid Redox Signal. 5(5):517-27.
Ali MA
,
McWeeney D
,
Milosavljević A
,
Jurka J
,
Jariwalla RJ
. 1991.
Enhanced malignant transformation induced by expression of a distinct protein domain of ribonucleotide reductase large subunit from herpes simplex virus type 2.
.
Proc Natl Acad Sci U S A. 88(18):8257-61.
Amino Acid Substitution
Al-Fageeh M
,
Li Q
,
W Dashwood M
,
Myzak MC
,
Dashwood RH
. 2004.
Phosphorylation and ubiquitination of oncogenic mutants of beta-catenin containing substitutions at Asp32.
.
Oncogene. 23(28):4839-46.
Leinweber B
,
Barofsky E
,
Barofsky DF
,
Ermilov V
,
Nylin K
,
Beckman JS
. 2004.
Aggregation of ALS mutant superoxide dismutase expressed in Escherichia coli.
.
Free Radic Biol Med. 36(7):911-8.
Amino Acids
Williams DE
. 2018.
Association Is Not Causation.
.
Toxicol Sci. 164(1):3.
Amino Acids, Sulfur
Muchiri RN
,
Kowal KE
,
Hensley K
,
Feinstein DL
,
van Breemen RB
. 2018.
Analysis of lanthionine ketimine ethyl ester in mouse serum, whole blood and tissues using ultrahigh-pressure liquid chromatography/tandem mass spectrometry.
.
Rapid Commun Mass Spectrom. 32(22):1941-1948.
AMP-Activated Protein Kinases
Butler JA
,
Hagen TM
,
Moreau R
. 2009.
Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and downregulating liver triacylglycerol secretion.
.
Arch Biochem Biophys. 485(1):63-71.
Amyloid beta-Peptides
Gray NE
,
Morré J
,
Kelley J
,
Maier CS
,
Stevens JF
,
Quinn JF
,
Soumyanath A
. 2014.
Caffeoylquinic acids in Centella asiatica protect against amyloid-β toxicity.
.
J Alzheimers Dis. 40(2):359-73.
Amyotrophic Lateral Sclerosis
Beckman JS
,
Esétvez AG
,
Barbeito L
,
Crow JP
. 2002.
CCS knockout mice establish an alternative source of copper for SOD in ALS.
.
Free Radic Biol Med. 33(10):1433-5.
Trumbull KA
,
McAllister D
,
Gandelman MM
,
Fung WY
,
Lew T
,
Brennan L
,
Lopez N
,
Morré J
,
Kalyanaraman B
,
Beckman JS
. 2012.
Diapocynin and apocynin administration fails to significantly extend survival in G93A SOD1 ALS mice.
.
Neurobiol Dis. 45(1):137-44.
Williams JR
,
Trias E
,
Beilby PR
,
Lopez NI
,
Labut EM
,
C Bradford S
,
Roberts BR
,
McAllum EJ
,
Crouch PJ
,
Rhoads TW
et al.
. 2016.
Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD(G93A) mice co-expressing the Copper-Chaperone-for-SOD.
.
Neurobiol Dis. 89:1-9.
Trias E
,
Ibarburu S
,
Barreto-Núñez R
,
Babdor J
,
Maciel TT
,
Guillo M
,
Gros L
,
Dubreuil P
,
Díaz-Amarilla P
,
Cassina P
et al.
. 2016.
Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis.
.
J Neuroinflammation. 13(1):177.
Kim MJin
,
Vargas MR
,
Harlan BA
,
Killoy KM
,
Ball LE
,
Comte-Walters S
,
Gooz M
,
Yamamoto Y
,
Beckman JS
,
Barbeito L
et al.
. 2018.
Nitration and Glycation Turn Mature NGF into a Toxic Factor for Motor Neurons: A Role for p75 and RAGE Signaling in ALS.
.
Antioxid Redox Signal. 28(18):1587-1602.
Trumbull KA
,
Beckman JS
. 2009.
A role for copper in the toxicity of zinc-deficient superoxide dismutase to motor neurons in amyotrophic lateral sclerosis.
.
Antioxid Redox Signal. 11(7):1627-39.
Kovacs M
,
Trias E
,
Varela V
,
Ibarburu S
,
Beckman JS
,
Moura IC
,
Hermine O
,
King PH
,
Si Y
,
Kwon Y
et al.
. 2019.
CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS.
.
Int J Mol Sci. 20(16)
Beckman JS
,
Estévez AG
,
Crow JP
,
Barbeito L
. 2001.
Superoxide dismutase and the death of motoneurons in ALS.
.
Trends Neurosci. 24(11 Suppl):S15-20.
Ermilova IP
,
Ermilov VB
,
Levy M
,
Ho E
,
Pereira C
,
Beckman JS
. 2005.
Protection by dietary zinc in ALS mutant G93A SOD transgenic mice.
.
Neurosci Lett. 379(1):42-6.
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